Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 Biomarker disease BEFREE Background This study aimed to investigate the usefulness of inflammatory biomarkers such as white blood cell (WBC) count, C-reactive protein (CRP) and procalcitonin (PCT) for differentiating cryptogenic organising pneumonia (COP) from community-acquired pneumonia (CAP). 31120857 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 Biomarker disease BEFREE Effect of Corticosteroids on C-Reactive Protein in Patients with Severe Community-Acquired Pneumonia and High Inflammatory Response: The Effect of Lymphopenia. 31540339 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 Biomarker disease BEFREE To comparatively analyze the usefulness of serum procalcitonin (PCT), C-reactive protein (CRP), soluble triggering receptor expressed on myeloid cells 1 (sTREM-1) and Clinical Pulmonary Infection Score (CPIS) for assessing the severity and prognosis of community-acquired pneumonia (CAP) in the elderly. 30366226 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 Biomarker disease BEFREE To identify predictors of complicated parapneumonic effusion (CPE)/empyema in patients of community acquired pneumonia (CAP) by using clinical and simple laboratory variables like hemoglobin (Hb), serum C-reactive protein (CRP), serum albumin (SA) levels and total leukocyte counts (TLC). 30182278 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 Biomarker disease BEFREE Lower long-term mortality in obese patients with community-acquired pneumonia: possible role of CRP. 31291389 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 Biomarker disease BEFREE Consecutive Measures of CRP Correlate with Length of Hospital Stay in Patients with Community-Acquired Pneumonia. 29911753 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 Biomarker disease BEFREE To investigate whether hemoglobin, white blood cell count (WBC), urea, sodium, albumin, and C-reactive protein at discharge in patients hospitalized for community-acquired pneumonia (CAP) are associated with 30-day readmission. 29600325 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 AlteredExpression disease BEFREE The moderate predictive value of serial serum CRP and PCT levels for the prognosis of hospitalized community-acquired pneumonia. 30285748 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 Biomarker disease BEFREE Failure of CRP decline within three days of hospitalization is associated with poor prognosis of Community-acquired Pneumonia. 27887037 2017
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 AlteredExpression disease BEFREE Impact of PCV13 on community-acquired pneumonia by C-reactive protein and procalcitonin levels in children. 28778617 2017
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 AlteredExpression disease BEFREE Procalcitonin and CRP levels were significantly higher in patients with community-acquired pneumonia presenting to the emergency department with indications for hospitalization than in patients with exacerbations of chronic obstructive pulmonary disease. 28680355 2017
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 Biomarker disease BEFREE CRP/IL-6/IL-10 Single-Nucleotide Polymorphisms Correlate with the Susceptibility and Severity of Community-Acquired Pneumonia. 27705004 2016
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 GeneticVariation disease BEFREE CRP gene variation and risk of community-acquired pneumonia. 19947988 2010
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.050 Biomarker disease BEFREE To analyze the value of cytokines (tumor necrosis factor [TNF]-α, interleukin [IL]-1β, IL-6, IL-8, IL-10) as predictors of mortality at 30 days in octogenarians and nonagenarians hospitalized in an internal medicine unit for community-acquired pneumonia (CAP). 31758443 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.050 Biomarker disease BEFREE MicroRNA‑124‑3p attenuates severe community‑acquired pneumonia progression in macrophages by targeting tumor necrosis factor receptor‑associated factor 6. 30535475 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.050 Biomarker disease BEFREE Comparison of the clinical characteristics and severity of community-acquired pneumonia between patients with rheumatoid arthritis treated with tocilizumab and those treated with TNF inhibitor. 30132358 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.050 Biomarker disease BEFREE Plasma concentrations of MCP-1, sCD14, IL-6, and IL-10 were significantly higher in patients with community-acquired pneumonia (CAP; <i>n</i> = 10) and infective endocarditis (IE; <i>n</i> = 11) compared to those with bacterial meningitis (BM; <i>n</i> = 18). 29769838 2018
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.050 GeneticVariation disease BEFREE The association of stable-state MR-proADM with severe acute exacerbations of COPD (AECOPDs) requiring hospitalization, or with community-acquired pneumonia (CAP) in patients with COPD, has not been studied yet. 29475034 2018
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.050 Biomarker disease BEFREE Impact of COPD on outcomes in hospitalized patients with community-acquired pneumonia: Analysis of the Spanish national hospital discharge database (2004-2013). 28615117 2017
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.050 Biomarker disease BEFREE Community-acquired pneumonia (CAP) is more common in patients with COPD than in the adult general population, with studies of hospitalized CAP patients consistently reporting COPD as a frequent comorbidity. 28176888 2017
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.050 GeneticVariation disease BEFREE Smoking increases the risk of community-acquired pneumonia (CAP) and is associated with the development of COPD. 28860737 2017
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.050 Biomarker disease BEFREE Taken together, the evidence suggests that pneumococcal and influenza vaccinations can prevent community-acquired pneumonia and acute exacerbations in COPD patients, while pneumococcal vaccination early in the course of COPD could help maintain stable health status. 29255353 2017
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.050 Biomarker disease BEFREE CRP/IL-6/IL-10 Single-Nucleotide Polymorphisms Correlate with the Susceptibility and Severity of Community-Acquired Pneumonia. 27705004 2016
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.050 Biomarker disease BEFREE IL6-174 G/C gene polymorphism and its relation to serum IL6 in Egyptian children with community-acquired pneumonia. 24725540 2014
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.050 Biomarker disease BEFREE We studied the genetic variability at IL6 in patients with community-acquired pneumonia (CAP) and pneumococcal CAP (P-CAP). 22113815 2012