Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
0.300 Biomarker phenotype CTD_human Pharmacological modulation of secondary mediator systems--cyclic AMP and cyclic GMP--on inflammatory hyperalgesia. 10401557 1999
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
0.300 Biomarker phenotype CTD_human Pharmacological modulation of secondary mediator systems--cyclic AMP and cyclic GMP--on inflammatory hyperalgesia. 10401557 1999
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
0.310 Biomarker phenotype CTD_human The involvement of K+ channels and Gi/o protein in the antinociceptive action of the gallic acid ethyl ester. 10499367 1999
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
0.300 Biomarker phenotype CTD_human The involvement of K+ channels and Gi/o protein in the antinociceptive action of the gallic acid ethyl ester. 10499367 1999
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
0.300 Biomarker phenotype CTD_human Oral antinociception and oedema inhibition produced by NPC 18884, a non-peptidic bradykinin B2 receptor antagonist. 10543429 1999
Entrez Id: 781
Gene Symbol: CACNA2D1
CACNA2D1
0.300 Biomarker phenotype CTD_human Upregulation of dorsal root ganglion (alpha)2(delta) calcium channel subunit and its correlation with allodynia in spinal nerve-injured rats. 11245671 2001
Entrez Id: 5731
Gene Symbol: PTGER1
PTGER1
0.300 Biomarker phenotype CTD_human Characterization of EP receptor subtypes responsible for prostaglandin E2-induced pain responses by use of EP1 and EP3 receptor knockout mice. 11375261 2001
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
0.300 Biomarker phenotype CTD_human Role of protein kinase Cepsilon and protein kinase A in a model of paclitaxel-induced painful peripheral neuropathy in the rat. 11738263 2001
Entrez Id: 887
Gene Symbol: CCKBR
CCKBR
0.300 Biomarker phenotype CTD_human Deletion of CCK2 receptor in mice results in an upregulation of the endogenous opioid system. 11880531 2002
Entrez Id: 7442
Gene Symbol: TRPV1
TRPV1
0.310 Biomarker phenotype CTD_human Peripheral group II metabotropic glutamate receptors (mGluR2/3) regulate prostaglandin E2-mediated sensitization of capsaicin responses and thermal nociception. 12151517 2002
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
0.310 Biomarker phenotype CTD_human Hyperalgesia during opioid abstinence: mediation by glutamate and substance p. 12351280 2002
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
0.300 Biomarker phenotype CTD_human Contribution of 5- and 12-lipoxygenase products to mechanical hyperalgesia induced by prostaglandin E(2) and epinephrine in the rat. 12582831 2003
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
0.300 Biomarker phenotype CTD_human Contribution of 5- and 12-lipoxygenase products to mechanical hyperalgesia induced by prostaglandin E(2) and epinephrine in the rat. 12582831 2003
Entrez Id: 239
Gene Symbol: ALOX12
ALOX12
0.300 Biomarker phenotype CTD_human Contribution of 5- and 12-lipoxygenase products to mechanical hyperalgesia induced by prostaglandin E(2) and epinephrine in the rat. 12582831 2003
Entrez Id: 5368
Gene Symbol: PNOC
PNOC
0.300 Biomarker phenotype CTD_human Nocistatin and prepro-nociceptin/orphanin FQ 160-187 cause nociception through activation of Gi/o in capsaicin-sensitive and of Gs in capsaicin-insensitive nociceptors, respectively. 12665541 2003
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.320 Biomarker phenotype CTD_human Hyperalgesia induced by Asp49 and Lys49 phospholipases A2 from Bothrops asper snake venom: pharmacological mediation and molecular determinants. 12727271 2003
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.310 Biomarker phenotype CTD_human Hyperalgesia induced by Asp49 and Lys49 phospholipases A2 from Bothrops asper snake venom: pharmacological mediation and molecular determinants. 12727271 2003
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
0.300 Biomarker phenotype CTD_human Hyperalgesia induced by Asp49 and Lys49 phospholipases A2 from Bothrops asper snake venom: pharmacological mediation and molecular determinants. 12727271 2003
Entrez Id: 796
Gene Symbol: CALCA
CALCA
0.310 Biomarker phenotype CTD_human Pharmacological sensitivity and gene expression analysis of the tibial nerve injury model of neuropathic pain. 12787826 2003
Entrez Id: 796
Gene Symbol: CALCA
CALCA
0.310 Therapeutic phenotype CTD_human Pharmacological sensitivity and gene expression analysis of the tibial nerve injury model of neuropathic pain. 12787826 2003
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
0.310 Biomarker phenotype CTD_human Pharmacological sensitivity and gene expression analysis of the tibial nerve injury model of neuropathic pain. 12787826 2003
Entrez Id: 51083
Gene Symbol: GAL
GAL
0.300 Biomarker phenotype CTD_human Pharmacological sensitivity and gene expression analysis of the tibial nerve injury model of neuropathic pain. 12787826 2003
Entrez Id: 7432
Gene Symbol: VIP
VIP
0.300 Biomarker phenotype CTD_human Pharmacological sensitivity and gene expression analysis of the tibial nerve injury model of neuropathic pain. 12787826 2003
Entrez Id: 796
Gene Symbol: CALCA
CALCA
0.310 Biomarker phenotype CTD_human The role of calcitonin gene-related peptide (CGRP) in the generation and maintenance of mechanical allodynia and hyperalgesia in rats after intradermal injection of capsaicin. 12855330 2003
Entrez Id: 796
Gene Symbol: CALCA
CALCA
0.310 Therapeutic phenotype CTD_human The role of calcitonin gene-related peptide (CGRP) in the generation and maintenance of mechanical allodynia and hyperalgesia in rats after intradermal injection of capsaicin. 12855330 2003