Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5617
Gene Symbol: PRL
PRL 		0.300 Biomarker disease CTD_human Correlation between plasma levels of prolactin and chlorpromazine in psychiatric patients. 240179 1975
Entrez Id: 7054
Gene Symbol: TH
TH 		0.300 Biomarker disease CTD_human Recessively inherited L-DOPA-responsive parkinsonism in infancy caused by a point mutation (L205P) in the tyrosine hydroxylase gene. 8817341 1996
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.300 Biomarker disease CTD_human Substituted hexahydrobenzo[f]thieno[c]quinolines as dopamine D1-selective agonists: synthesis and biological evaluation in vitro and in vivo. 9171869 1997
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.300 Therapeutic disease CTD_human Substituted hexahydrobenzo[f]thieno[c]quinolines as dopamine D1-selective agonists: synthesis and biological evaluation in vitro and in vivo. 9171869 1997
Entrez Id: 2668
Gene Symbol: GDNF
GDNF 		0.300 Therapeutic disease CTD_human Glial cell line-derived neurotrophic factor-levodopa interactions and reduction of side effects in parkinsonian monkeys. 9266731 1997
Entrez Id: 6622
Gene Symbol: SNCA
SNCA 		0.370 GeneticVariation disease BEFREE A specific mutation (A53T) in the encoding region for alpha-synuclein has been identified in a large multigenerational family with an autosomal dominant parkinsonism known as the Contursi kindred. 9878203 1998
Entrez Id: 5173
Gene Symbol: PDYN
PDYN 		0.300 Biomarker disease CTD_human Differential regulation of striatal preproenkephalin and preprotachykinin mRNA levels in MPTP-lesioned monkeys chronically treated with dopamine D1 or D2 receptor agonists. 9930741 1999
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		0.300 Biomarker disease CTD_human A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease. 10072423 1999
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		0.300 Therapeutic disease CTD_human A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease. 10072423 1999
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		0.300 Biomarker disease CTD_human Two brothers with frontotemporal dementia and parkinsonism with an N279K mutation of the tau gene. 10802785 2000
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		0.300 Biomarker disease CTD_human Parkin deletions in a family with adult-onset, tremor-dominant parkinsonism: expanding the phenotype. 10894217 2000
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		0.300 Therapeutic disease CTD_human Parkin deletions in a family with adult-onset, tremor-dominant parkinsonism: expanding the phenotype. 10894217 2000
Entrez Id: 6622
Gene Symbol: SNCA
SNCA 		0.370 Biomarker disease BEFREE The co-localization of NACP/alpha-synuclein and tau epitopes was examined in the brain stem and hippocampal formation in two patients from a family of autosomal dominant parkinsonism and dementia with Lewy bodies (LBs) without two reported missense mutations in the NACP gene. 10963357 2000
Entrez Id: 7054
Gene Symbol: TH
TH 		0.300 Biomarker disease CTD_human Four novel mutations in the tyrosine hydroxylase gene in patients with infantile parkinsonism. 11246459 2000
Entrez Id: 65018
Gene Symbol: PINK1
PINK1 		0.300 Biomarker disease CTD_human Localization of a novel locus for autosomal recessive early-onset parkinsonism, PARK6, on human chromosome 1p35-p36. 11254447 2001
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		0.300 Biomarker disease CTD_human Localization of a novel locus for autosomal recessive early-onset parkinsonism, PARK6, on human chromosome 1p35-p36. 11254447 2001
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		0.300 Therapeutic disease CTD_human Localization of a novel locus for autosomal recessive early-onset parkinsonism, PARK6, on human chromosome 1p35-p36. 11254447 2001
Entrez Id: 6622
Gene Symbol: SNCA
SNCA 		0.370 Biomarker disease BEFREE Analysis of alpha-synuclein, parkin, tau, and UCH-L1 in a Japanese family with autosomal dominant parkinsonism. 11455179 2001
Entrez Id: 7345
Gene Symbol: UCHL1
UCHL1 		0.010 Biomarker disease BEFREE Analysis of alpha-synuclein, parkin, tau, and UCH-L1 in a Japanese family with autosomal dominant parkinsonism. 11455179 2001
Entrez Id: 2668
Gene Symbol: GDNF
GDNF 		0.300 Therapeutic disease CTD_human Behavioral improvement and dopamine release in a Parkinsonian rat model. 12213621 2002
Entrez Id: 6622
Gene Symbol: SNCA
SNCA 		0.370 GeneticVariation disease BEFREE In the same year, from the identification of mutation in the alpha-synuclein gene in rare pedigrees with autosomal dominant parkinsonism, arose the concept that Parkinson's disease may be part of a broader group of 'synucleinopathies', in which there is a fundamental defect in protein processing. 12378057 2001
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.300 Biomarker disease CTD_human Dopamine D2S and D2L receptors may differentially contribute to the actions of antipsychotic and psychotic agents in mice. 12476322 2002
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.300 Therapeutic disease CTD_human Dopamine D2S and D2L receptors may differentially contribute to the actions of antipsychotic and psychotic agents in mice. 12476322 2002
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		0.300 Therapeutic disease CTD_human Parkin disease: a phenotypic study of a large case series. 12764051 2003
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		0.300 Biomarker disease CTD_human Parkin disease: a phenotypic study of a large case series. 12764051 2003