Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1981
Gene Symbol: EIF4G1
EIF4G1 		0.010 GeneticVariation disease BEFREE Pathogenic mutations in the EIF4G1 gene were recently reported as a cause of autosomal dominant parkinsonism. 24704100 2014
Entrez Id: 6623
Gene Symbol: SNCG
SNCG 		0.010 Biomarker disease BEFREE Autosomal dominant parkinsonism associated with variable synuclein and tau pathology. 15136696 2004
Entrez Id: 6620
Gene Symbol: SNCB
SNCB 		0.010 Biomarker disease BEFREE Autosomal dominant parkinsonism associated with variable synuclein and tau pathology. 15136696 2004
Entrez Id: 7345
Gene Symbol: UCHL1
UCHL1 		0.010 Biomarker disease BEFREE Analysis of alpha-synuclein, parkin, tau, and UCH-L1 in a Japanese family with autosomal dominant parkinsonism. 11455179 2001
Entrez Id: 6311
Gene Symbol: ATXN2
ATXN2 		0.020 GeneticVariation disease BEFREE We screened 164 families with ADP for expansions in the SCA2, 3, and 17 genes and for the G2019S mutation in LRRK2. 17568014 2007
Entrez Id: 4061
Gene Symbol: LY6E
LY6E 		0.020 GeneticVariation disease BEFREE We screened 164 families with ADP for expansions in the SCA2, 3, and 17 genes and for the G2019S mutation in LRRK2. 17568014 2007
Entrez Id: 6311
Gene Symbol: ATXN2
ATXN2 		0.020 GeneticVariation disease BEFREE We identified one pathogenic expansion in SCA-2 in a North American family with autosomal dominant parkinsonism. 15911147 2005
Entrez Id: 4061
Gene Symbol: LY6E
LY6E 		0.020 GeneticVariation disease BEFREE We identified one pathogenic expansion in SCA-2 in a North American family with autosomal dominant parkinsonism. 15911147 2005
Entrez Id: 5368
Gene Symbol: PNOC
PNOC 		0.300 Biomarker disease CTD_human Nociceptin/Orphanin FQ Inhibits the Survival and Axon Growth of Midbrain Dopaminergic Neurons Through a p38-MAPK Dependent Mechanism. 26687234 2016
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		0.300 Therapeutic disease CTD_human Methylmercury can induce Parkinson's-like neurotoxicity similar to 1-methyl-4- phenylpyridinium: a genomic and proteomic analysis on MN9D dopaminergic neuron cells. 26558463 2015
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		0.300 Therapeutic disease CTD_human A recurrent mutation in PARK2 is associated with familial lung cancer. 25640678 2015
Entrez Id: 27429
Gene Symbol: HTRA2
HTRA2 		0.300 Biomarker disease CTD_human Methylmercury can induce Parkinson's-like neurotoxicity similar to 1-methyl-4- phenylpyridinium: a genomic and proteomic analysis on MN9D dopaminergic neuron cells. 26558463 2015
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		0.300 Biomarker disease CTD_human A recurrent mutation in PARK2 is associated with familial lung cancer. 25640678 2015
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		0.300 Biomarker disease CTD_human Methylmercury can induce Parkinson's-like neurotoxicity similar to 1-methyl-4- phenylpyridinium: a genomic and proteomic analysis on MN9D dopaminergic neuron cells. 26558463 2015
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.300 Biomarker disease CTD_human Methylmercury can induce Parkinson's-like neurotoxicity similar to 1-methyl-4- phenylpyridinium: a genomic and proteomic analysis on MN9D dopaminergic neuron cells. 26558463 2015
Entrez Id: 2629
Gene Symbol: GBA
GBA 		0.300 Biomarker disease CTD_human Selective loss of glucocerebrosidase activity in sporadic Parkinson's disease and dementia with Lewy bodies. 25881142 2015
Entrez Id: 55532
Gene Symbol: SLC30A10
SLC30A10 		0.300 Biomarker disease CTD_human Manganese-Induced Parkinsonism Is Not Idiopathic Parkinson's Disease: Environmental and Genetic Evidence. 26220508 2015
Entrez Id: 65018
Gene Symbol: PINK1
PINK1 		0.300 Biomarker disease CTD_human Methylmercury can induce Parkinson's-like neurotoxicity similar to 1-methyl-4- phenylpyridinium: a genomic and proteomic analysis on MN9D dopaminergic neuron cells. 26558463 2015
Entrez Id: 65018
Gene Symbol: PINK1
PINK1 		0.300 Biomarker disease CTD_human Downregulation of Pink1 influences mitochondrial fusion-fission machinery and sensitizes to neurotoxins in dopaminergic cells. 24792327 2014
Entrez Id: 216
Gene Symbol: ALDH1A1
ALDH1A1 		0.300 Biomarker disease CTD_human Benomyl, aldehyde dehydrogenase, DOPAL, and the catecholaldehyde hypothesis for the pathogenesis of Parkinson's disease. 25045800 2014
Entrez Id: 65018
Gene Symbol: PINK1
PINK1 		0.300 Biomarker disease CTD_human Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson's disease. 24441527 2014
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2 		0.300 Biomarker disease CTD_human Benomyl, aldehyde dehydrogenase, DOPAL, and the catecholaldehyde hypothesis for the pathogenesis of Parkinson's disease. 25045800 2014
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.300 Biomarker disease CTD_human Low doses of paraquat and polyphenols prolong life span and locomotor activity in knock-down parkin Drosophila melanogaster exposed to oxidative stress stimuli: implication in autosomal recessive juvenile parkinsonism. 23046578 2013
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		0.300 Therapeutic disease CTD_human Low doses of paraquat and polyphenols prolong life span and locomotor activity in knock-down parkin Drosophila melanogaster exposed to oxidative stress stimuli: implication in autosomal recessive juvenile parkinsonism. 23046578 2013
Entrez Id: 65018
Gene Symbol: PINK1
PINK1 		0.300 Biomarker disease CTD_human Low doses of paraquat and polyphenols prolong life span and locomotor activity in knock-down parkin Drosophila melanogaster exposed to oxidative stress stimuli: implication in autosomal recessive juvenile parkinsonism. 23046578 2013