Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 216
Gene Symbol: ALDH1A1
ALDH1A1
0.300 Biomarker disease CTD_human Benomyl, aldehyde dehydrogenase, DOPAL, and the catecholaldehyde hypothesis for the pathogenesis of Parkinson's disease. 25045800 2014
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2
0.300 Biomarker disease CTD_human Benomyl, aldehyde dehydrogenase, DOPAL, and the catecholaldehyde hypothesis for the pathogenesis of Parkinson's disease. 25045800 2014
Entrez Id: 23400
Gene Symbol: ATP13A2
ATP13A2
0.300 Biomarker disease CTD_human Low doses of paraquat and polyphenols prolong life span and locomotor activity in knock-down parkin Drosophila melanogaster exposed to oxidative stress stimuli: implication in autosomal recessive juvenile parkinsonism. 23046578 2013
Entrez Id: 478
Gene Symbol: ATP1A3
ATP1A3
0.300 Biomarker disease CTD_human Mutations in the Na+/K+ -ATPase alpha3 gene ATP1A3 are associated with rapid-onset dystonia parkinsonism. 15260953 2004
Entrez Id: 1639
Gene Symbol: DCTN1
DCTN1
0.300 Biomarker disease CTD_human DCTN1 mutations in Perry syndrome. 19136952 2009
Entrez Id: 1644
Gene Symbol: DDC
DDC
0.300 Therapeutic disease CTD_human Vesicular monoamine transporter-2 and aromatic L-amino acid decarboxylase gene therapy prevents development of motor complications in parkinsonian rats after chronic intermittent L-3,4-dihydroxyphenylalanine administration. 16269145 2006
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.300 Therapeutic disease CTD_human Dopamine D2S and D2L receptors may differentially contribute to the actions of antipsychotic and psychotic agents in mice. 12476322 2002
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.300 Biomarker disease CTD_human Substituted hexahydrobenzo[f]thieno[c]quinolines as dopamine D1-selective agonists: synthesis and biological evaluation in vitro and in vivo. 9171869 1997
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.300 Therapeutic disease CTD_human Thiethylperazine-induced parkinsonism: in vivo demonstration of dopamine D2 receptors blockade. 15469457 2004
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.300 Biomarker disease CTD_human Thiethylperazine-induced parkinsonism: in vivo demonstration of dopamine D2 receptors blockade. 15469457 2004
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.300 Therapeutic disease CTD_human Substituted hexahydrobenzo[f]thieno[c]quinolines as dopamine D1-selective agonists: synthesis and biological evaluation in vitro and in vivo. 9171869 1997
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.300 Biomarker disease CTD_human Dopamine D2S and D2L receptors may differentially contribute to the actions of antipsychotic and psychotic agents in mice. 12476322 2002
Entrez Id: 2629
Gene Symbol: GBA
GBA
0.300 Biomarker disease CTD_human Selective loss of glucocerebrosidase activity in sporadic Parkinson's disease and dementia with Lewy bodies. 25881142 2015
Entrez Id: 2668
Gene Symbol: GDNF
GDNF
0.300 Therapeutic disease CTD_human Behavioral improvement and dopamine release in a Parkinsonian rat model. 12213621 2002
Entrez Id: 2668
Gene Symbol: GDNF
GDNF
0.300 Therapeutic disease CTD_human Glial cell line-derived neurotrophic factor-levodopa interactions and reduction of side effects in parkinsonian monkeys. 9266731 1997
Entrez Id: 2936
Gene Symbol: GSR
GSR
0.300 Therapeutic disease CTD_human Protective role of glutathione reductase in paraquat induced neurotoxicity. 22721943 2012
Entrez Id: 27429
Gene Symbol: HTRA2
HTRA2
0.300 Biomarker disease CTD_human Methylmercury can induce Parkinson's-like neurotoxicity similar to 1-methyl-4- phenylpyridinium: a genomic and proteomic analysis on MN9D dopaminergic neuron cells. 26558463 2015
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
0.300 Biomarker disease CTD_human Low doses of paraquat and polyphenols prolong life span and locomotor activity in knock-down parkin Drosophila melanogaster exposed to oxidative stress stimuli: implication in autosomal recessive juvenile parkinsonism. 23046578 2013
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
0.300 Biomarker disease CTD_human Methylmercury can induce Parkinson's-like neurotoxicity similar to 1-methyl-4- phenylpyridinium: a genomic and proteomic analysis on MN9D dopaminergic neuron cells. 26558463 2015
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
0.300 Biomarker disease CTD_human G2019S LRRK2 mutant fibroblasts from Parkinson's disease patients show increased sensitivity to neurotoxin 1-methyl-4-phenylpyridinium dependent of autophagy. 25017139 2014
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
0.300 Biomarker disease CTD_human Familial aggregation of parkinsonism in progressive supranuclear palsy. 19458322 2009
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
0.300 Biomarker disease CTD_human Two brothers with frontotemporal dementia and parkinsonism with an N279K mutation of the tau gene. 10802785 2000
Entrez Id: 4803
Gene Symbol: NGF
NGF
0.300 Therapeutic disease CTD_human Brain targeting of nerve growth factor using poly(butyl cyanoacrylate) nanoparticles. 19694610 2009
Entrez Id: 11315
Gene Symbol: PARK7
PARK7
0.300 Biomarker disease CTD_human Low doses of paraquat and polyphenols prolong life span and locomotor activity in knock-down parkin Drosophila melanogaster exposed to oxidative stress stimuli: implication in autosomal recessive juvenile parkinsonism. 23046578 2013
Entrez Id: 11315
Gene Symbol: PARK7
PARK7
0.300 Biomarker disease CTD_human Methylmercury can induce Parkinson's-like neurotoxicity similar to 1-methyl-4- phenylpyridinium: a genomic and proteomic analysis on MN9D dopaminergic neuron cells. 26558463 2015