Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2896
Gene Symbol: GRN
GRN
0.010 AlteredExpression group BEFREE An intra-peritoneal LPS challenge in mice did not affect adipose tissue progranulin expression, whereas peritoneal infection by S. aureus increased progranulin expression after 24 h. 31454754 2020
Entrez Id: 2919
Gene Symbol: CXCL1
CXCL1
0.010 Biomarker group BEFREE In a murine model of peritoneal infection, the particulate form of the staphylococcal cell envelope (PCE) induced the production of chemokine (C-X-C motif) ligand 1 (CXCL1) and CC chemokine ligand 2 (CCL2), the chemotactic cytokines for neutrophils and monocytes, respectively, resulting in a strong influx of the phagocytes into the peritoneal cavity. 31548327 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.010 AlteredExpression group BEFREE The exception was the enhanced compartmentalized expression of IL-1β for the resistant mice (S/C-KO) after peritoneal infection. 24498223 2014
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
0.010 Biomarker group BEFREE Marco and tlr2 -/- mice were more resistant to peritoneal infection but more susceptible to pulmonary infection than wild type mice. 24498223 2014
Entrez Id: 4481
Gene Symbol: MSR1
MSR1
0.010 Biomarker group BEFREE Using double SR-A/CD36 knockout mice (S/C-KO) and S. aureus strain HG001, a clinically relevant non-mutagenized strain, we showed that the absence of these two scavenger receptors was protective in peritoneal infection. 24498223 2014
Entrez Id: 406947
Gene Symbol: MIR155
MIR155
0.010 Biomarker group BEFREE Specific dysregulation of miR-155, -146a, -142-3p, -299, and -200c -132 and -21 with their corresponding effects on the TLR and NF-κB signaling pathways during inflammation, suggests a plausible mechanism for tolerance in this novel chronic model with persistent peritoneal infection. 23060456 2013
Entrez Id: 3929
Gene Symbol: LBP
LBP
0.010 Biomarker group BEFREE In this study, we show that innate defense against a lethal peritoneal infection with Salmonella requires a direct proinflammatory involvement of LBP, and that this is a major nonredundant function of LBP in this infection model. 11466385 2001