×
Entrez Id:
3091
Gene Symbol:
HIF1A
HIF1A
0.050
Biomarker
disease
BEFREE
In a model of renal ischemia -reperfusion injury, xenon provided morphologic and functional renoprotection; hydrodynamic injection of HIF-1alpha small interfering RNA demonstrated that this protection is HIF-1alpha dependent.
19144758
2009
×
Entrez Id:
3091
Gene Symbol:
HIF1A
HIF1A
0.050
Biomarker
disease
BEFREE
Hypoxia inducible factor 1-alpha (HIF-1 alpha ) is induced during reperfusion after renal ischemia and is critical for proximal tubule cell survival.
22432008
2012
×
Entrez Id:
3091
Gene Symbol:
HIF1A
HIF1A
0.050
Biomarker
disease
BEFREE
Inhibitor of DNA Binding 1 Is Induced during Kidney Ischemia -Reperfusion and Is Critical for the Induction of Hypoxia-Inducible Factor-1α .
27127787
2016
×
Entrez Id:
3091
Gene Symbol:
HIF1A
HIF1A
0.050
Biomarker
disease
BEFREE
A novel role of HIF-1α /PROX-1/LYVE-1 axis on tissue regeneration after renal ischaemia /reperfusion in mice.
29633855
2019
×
Entrez Id:
3091
Gene Symbol:
HIF1A
HIF1A
0.050
Biomarker
disease
BEFREE
Ferulic Acid Protected from Kidney Ischemia Reperfusion Injury in Mice: Possible Mechanism Through Increasing Adenosine Generation via HIF-1α .
30143933
2018
×
Entrez Id:
7099
Gene Symbol:
TLR4
TLR4
0.030
AlteredExpression
disease
BEFREE
Crocin reverses unilateral renal ischemia reperfusion injury-induced augmentation of oxidative stress and toll like receptor-4 activity.
29625388
2018
×
Entrez Id:
7099
Gene Symbol:
TLR4
TLR4
0.030
Biomarker
disease
BEFREE
However, HMGB1 blockade in a renal ischemia reperfusion model reduced pulmonary neutrophil infiltration independent from TLR4 .
24646859
2014
×
Entrez Id:
7099
Gene Symbol:
TLR4
TLR4
0.030
Biomarker
disease
BEFREE
Up-Regulation of HMGB1 Exacerbates Renal Ischemia -Reperfusion Injury by Stimulating Inflammatory and Immune Responses through the TLR4 Signaling Pathway in Mice.
28472797
2017
×
Entrez Id:
406991
Gene Symbol:
MIR21
MIR21
0.020
Biomarker
disease
BEFREE
AR/miR-21 axis could be a potential therapeutic target for the kidney ischemia injury.
31632533
2019
×
Entrez Id:
7097
Gene Symbol:
TLR2
TLR2
0.020
Biomarker
disease
BEFREE
Systemic TLR2 Antibody Application in Renal Ischaemia and Reperfusion Injury Decreases AKT Phosphorylation and Increases Apoptosis in the Mouse Kidney.
28857508
2018
×
Entrez Id:
8562
Gene Symbol:
DENR
DENR
0.020
Biomarker
disease
BEFREE
Renal ischemia /reperfusion-induced mitophagy protects against renal dysfunction via Drp1 -dependent-pathway.
29704468
2018
×
Entrez Id:
7402
Gene Symbol:
UTRN
UTRN
0.020
Biomarker
disease
BEFREE
Renal ischemia /reperfusion-induced mitophagy protects against renal dysfunction via Drp1 -dependent-pathway.
29704468
2018
×
Entrez Id:
6347
Gene Symbol:
CCL2
CCL2
0.020
Biomarker
disease
BEFREE
Subendothelial heparan sulfate proteoglycans become major L-selectin and monocyte chemoattractant protein-1 ligands upon renal ischemia /reperfusion.
17525255
2007
×
Entrez Id:
23604
Gene Symbol:
DAPK2
DAPK2
0.020
AlteredExpression
disease
BEFREE
We recently found dysregulation of mitochondrial dynamics caused by increased Drp1 expression and cellular apoptosis of the heart in an experimental AKI animal model of renal ischemia -reperfusion.
27349577
2016
×
Entrez Id:
6347
Gene Symbol:
CCL2
CCL2
0.020
AlteredExpression
disease
BEFREE
Exosomal ATF3 RNA attenuates pro-inflammatory gene MCP-1 transcription in renal ischemia -reperfusion.
24420912
2014
×
Entrez Id:
3162
Gene Symbol:
HMOX1
HMOX1
0.020
Biomarker
disease
BEFREE
Upregulation of heme oxygenase 1 (HO-1 ) attenuates kidney damage, oxidative stress and inflammatory reaction during renal ischemia / reperfusion injury.
29593125
2018
×
Entrez Id:
90865
Gene Symbol:
IL33
IL33
0.020
Biomarker
disease
BEFREE
We examined the role of the nuclear alarmin IL-33 in tissue injury and innate immune response triggered by experimental kidney ischemia -reperfusion.
29436517
2018
×
Entrez Id:
90865
Gene Symbol:
IL33
IL33
0.020
Biomarker
disease
BEFREE
Potentiating Tissue-Resident Type 2 Innate Lymphoid Cells by IL-33 to Prevent Renal Ischemia -Reperfusion Injury.
29295873
2018
×
Entrez Id:
23604
Gene Symbol:
DAPK2
DAPK2
0.020
Biomarker
disease
BEFREE
Renal ischemia /reperfusion-induced mitophagy protects against renal dysfunction via Drp1 -dependent-pathway.
29704468
2018
×
Entrez Id:
2056
Gene Symbol:
EPO
EPO
0.020
Biomarker
disease
BEFREE
We postulate that chronic intermittent hypotension and renal ischemia may lead to erythropoietin secretion, and this cascade could represent a newly recognized cause of secondary erythrocytosis.
31266452
2019
×
Entrez Id:
3146
Gene Symbol:
HMGB1
HMGB1
0.020
AlteredExpression
disease
BEFREE
Up-Regulation of HMGB1 Exacerbates Renal Ischemia -Reperfusion Injury by Stimulating Inflammatory and Immune Responses through the TLR4 Signaling Pathway in Mice.
28472797
2017
×
Entrez Id:
8562
Gene Symbol:
DENR
DENR
0.020
AlteredExpression
disease
BEFREE
We recently found dysregulation of mitochondrial dynamics caused by increased Drp1 expression and cellular apoptosis of the heart in an experimental AKI animal model of renal ischemia -reperfusion.
27349577
2016
×
Entrez Id:
406991
Gene Symbol:
MIR21
MIR21
0.020
AlteredExpression
disease
BEFREE
Accumulating evidence suggests that miR-21 overexpression protects against kidney ischemia injury.
30013485
2018
×
Entrez Id:
3586
Gene Symbol:
IL10
IL10
0.020
Biomarker
disease
BEFREE
Infusion of IL-10 -expressing cells protects against renal ischemia through induction of lipocalin-2.
22278021
2012
×
Entrez Id:
10059
Gene Symbol:
DNM1L
DNM1L
0.020
Biomarker
disease
BEFREE
Renal ischemia /reperfusion-induced mitophagy protects against renal dysfunction via Drp1 -dependent-pathway.
29704468
2018