Source: CURATED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4233
Gene Symbol: MET
MET 		0.800 SomaticCausalMutation disease ORPHANET Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma. 26536169 2016
Entrez Id: 4233
Gene Symbol: MET
MET 		0.800 Biomarker disease CTD_human Spectrum of diverse genomic alterations define non-clear cell renal carcinoma subtypes. 25401301 2015
Entrez Id: 4233
Gene Symbol: MET
MET 		0.800 Biomarker disease CLINGEN c-Met inhibitors with novel binding mode show activity against several hereditary papillary renal cell carcinoma-related mutations. 18055465 2008
Entrez Id: 4233
Gene Symbol: MET
MET 		0.800 Biomarker disease CLINGEN The MET oncogene drives a genetic programme linking cancer to haemostasis. 15772665 2005
Entrez Id: 4233
Gene Symbol: MET
MET 		0.800 Biomarker disease CLINGEN Activating Met mutations produce unique tumor profiles in mice with selective duplication of the mutant allele. 15557554 2004
Entrez Id: 4233
Gene Symbol: MET
MET 		0.800 Biomarker disease CLINGEN Hereditary and sporadic papillary renal carcinomas with c-met mutations share a distinct morphological phenotype. 10433944 1999
Entrez Id: 4233
Gene Symbol: MET
MET 		0.800 Biomarker disease CLINGEN Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas. 9140397 1997
Entrez Id: 4233
Gene Symbol: MET
MET 		0.800 Biomarker disease CLINGEN Activating mutations for the met tyrosine kinase receptor in human cancer. 9326629 1997
Entrez Id: 4233
Gene Symbol: MET
MET 		0.800 Biomarker disease CLINGEN The receptor encoded by the human c-MET oncogene is expressed in hepatocytes, epithelial cells and solid tumors. 1917129 1991
Entrez Id: 4233
Gene Symbol: MET
MET 		0.800 CausalMutation disease CGI
Entrez Id: 4286
Gene Symbol: MITF
MITF 		0.500 SusceptibilityMutation disease ORPHANET A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma. 22012259 2011
Entrez Id: 4286
Gene Symbol: MITF
MITF 		0.500 Biomarker disease CTD_human A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma. 22012259 2011
Entrez Id: 5546
Gene Symbol: PRCC
PRCC 		0.430 Biomarker disease CTD_human
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.370 Biomarker disease CTD_human NADPH oxidase NOX4 supports renal tumorigenesis by promoting the expression and nuclear accumulation of HIF2α. 24755467 2014
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.370 Biomarker disease CTD_human Integrated molecular analysis of clear-cell renal cell carcinoma. 23797736 2013
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.370 Biomarker disease CTD_human Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma. 22138691 2011
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.370 Biomarker disease CTD_human L1-CAM expression in ccRCC correlates with shorter patients survival times and confers chemoresistance in renal cell carcinoma cells. 21097529 2011
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.370 Biomarker disease CTD_human Bilateral renal-cell carcinoma associated with an acquired VHL mutation and long-term trichloroethylene exposure. 19473641 2009
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.370 Biomarker disease CTD_human VHL mutations in renal cell cancer: does occupational exposure to trichloroethylene make a difference? 15177666 2004
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.370 Biomarker disease CTD_human Role of transforming growth factor-alpha in von Hippel--Lindau (VHL)(-/-) clear cell renal carcinoma cell proliferation: a possible mechanism coupling VHL tumor suppressor inactivation and tumorigenesis. 11171960 2001
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.370 Biomarker disease CTD_human Trichloroethylene exposure and specific somatic mutations in patients with renal cell carcinoma. 10340905 1999
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.370 Biomarker disease CTD_human Renal cell carcinomas in trichloroethene (TRI) exposed persons are associated with somatic mutations in the von Hippel-Lindau (VHL) tumour suppressor gene. 9137812 1997
Entrez Id: 7030
Gene Symbol: TFE3
TFE3 		0.360 Biomarker disease CTD_human
Entrez Id: 3855
Gene Symbol: KRT7
KRT7 		0.320 Biomarker disease CTD_human Diagnostic value of cytokeratin 7 and parvalbumin in differentiating chromophobe renal cell carcinoma from renal oncocytoma. 16927643 2006
Entrez Id: 3855
Gene Symbol: KRT7
KRT7 		0.320 Biomarker disease CTD_human Differential protein profiling in renal-cell carcinoma. 15108329 2004