Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5627
Gene Symbol: PROS1
PROS1
0.100 Biomarker disease BEFREE PSA time to nadir as a prognostic factor of first-line docetaxel treatment in castration-resistant prostate cancer: Multicenter validation in patients from the Chinese Prostate Cancer Consortium. 31672485 2020
Entrez Id: 5324
Gene Symbol: PLAG1
PLAG1
0.100 Biomarker disease BEFREE PSA time to nadir as a prognostic factor of first-line docetaxel treatment in castration-resistant prostate cancer: Multicenter validation in patients from the Chinese Prostate Cancer Consortium. 31672485 2020
Entrez Id: 9520
Gene Symbol: NPEPPS
NPEPPS
0.100 Biomarker disease BEFREE On multivariable analysis, higher PSA at castrate-resistant prostate cancer (4.67 vs. 4.4ng/mL, OR=0.57, P=0.02), shorter time from castrate-resistant prostate cancer to scan (7.9 vs. 14.6 months, OR=0.97, P=0.006) and higher PSA at scan (OR=2.91, P<0.0001) were significantly predictive of bone scan positivity. 31851457 2020
Entrez Id: 9520
Gene Symbol: NPEPPS
NPEPPS
0.100 Biomarker disease BEFREE PSA time to nadir as a prognostic factor of first-line docetaxel treatment in castration-resistant prostate cancer: Multicenter validation in patients from the Chinese Prostate Cancer Consortium. 31672485 2020
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
0.100 Biomarker disease BEFREE GGNBP2 overexpression affects the growth of castration-resistant prostate cancer via the PI3K/Akt signalling pathway. 31797427 2020
Entrez Id: 367
Gene Symbol: AR
AR
0.100 Biomarker disease BEFREE Enzalutamide and apalutamide are two androgen receptor inhibitors approved for the treatment of castration-resistant prostate cancer (CRPC) and nonmetastatic castration-resistant prostate cancer (nmCRPC), respectively. 31538772 2020
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
0.100 Biomarker disease BEFREE GGNBP2 overexpression affects the growth of castration-resistant prostate cancer via the PI3K/Akt signalling pathway. 31797427 2020
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
0.100 Biomarker disease BEFREE Activation of the PI3K-Akt-mTOR signaling pathway is common in advanced castration resistant prostate cancer (CRPC), typically through PTEN loss. 31522863 2020
Entrez Id: 2346
Gene Symbol: FOLH1
FOLH1
0.100 Biomarker disease BEFREE Currently, prostate-specific membrane antigen-radioligand therapy (PSMA-RLT) is considered a last-line treatment option in advanced castration-resistant prostate cancer. 31579967 2020
Entrez Id: 354
Gene Symbol: KLK3
KLK3
0.100 Biomarker disease BEFREE On multivariable analysis, higher PSA at castrate-resistant prostate cancer (4.67 vs. 4.4ng/mL, OR=0.57, P=0.02), shorter time from castrate-resistant prostate cancer to scan (7.9 vs. 14.6 months, OR=0.97, P=0.006) and higher PSA at scan (OR=2.91, P<0.0001) were significantly predictive of bone scan positivity. 31851457 2020
Entrez Id: 2346
Gene Symbol: FOLH1
FOLH1
0.100 Biomarker disease BEFREE Asymptomatic Metastasis to Thyroid Cartilage Detected by 18F-Choline and 64Cu-PSMA PET/CT as a Single Site of Disease Relapse in a Patient With Castration-Resistant Prostate Carcinoma. 31652161 2020
Entrez Id: 29968
Gene Symbol: PSAT1
PSAT1
0.100 Biomarker disease BEFREE On multivariable analysis, higher PSA at castrate-resistant prostate cancer (4.67 vs. 4.4ng/mL, OR=0.57, P=0.02), shorter time from castrate-resistant prostate cancer to scan (7.9 vs. 14.6 months, OR=0.97, P=0.006) and higher PSA at scan (OR=2.91, P<0.0001) were significantly predictive of bone scan positivity. 31851457 2020
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.100 Biomarker disease BEFREE Activation of the PI3K-Akt-mTOR signaling pathway is common in advanced castration resistant prostate cancer (CRPC), typically through PTEN loss. 31522863 2020
Entrez Id: 29968
Gene Symbol: PSAT1
PSAT1
0.100 Biomarker disease BEFREE PSA time to nadir as a prognostic factor of first-line docetaxel treatment in castration-resistant prostate cancer: Multicenter validation in patients from the Chinese Prostate Cancer Consortium. 31672485 2020
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
0.100 Biomarker disease BEFREE GGNBP2 overexpression affects the growth of castration-resistant prostate cancer via the PI3K/Akt signalling pathway. 31797427 2020
Entrez Id: 367
Gene Symbol: AR
AR
0.100 Biomarker disease BEFREE KIF4A promotes castration-sensitive and castration-resistant prostate cancer cell growth through AR- and AR-V7-dependent signaling. 31796514 2020
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
0.100 Biomarker disease BEFREE Activation of the PI3K-Akt-mTOR signaling pathway is common in advanced castration resistant prostate cancer (CRPC), typically through PTEN loss. 31522863 2020
Entrez Id: 354
Gene Symbol: KLK3
KLK3
0.100 Biomarker disease BEFREE PSA time to nadir as a prognostic factor of first-line docetaxel treatment in castration-resistant prostate cancer: Multicenter validation in patients from the Chinese Prostate Cancer Consortium. 31672485 2020
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.100 Biomarker disease BEFREE β-catenin activation, independent of the cell-of-origin, cooperated with Pten loss to drive AR-independent castration-resistant prostate cancer. 31719098 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.100 Biomarker disease BEFREE GGNBP2 overexpression affects the growth of castration-resistant prostate cancer via the PI3K/Akt signalling pathway. 31797427 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.100 Biomarker disease BEFREE Activation of the PI3K-Akt-mTOR signaling pathway is common in advanced castration resistant prostate cancer (CRPC), typically through PTEN loss. 31522863 2020
Entrez Id: 367
Gene Symbol: AR
AR
0.100 Biomarker disease BEFREE Therefore, finding key molecules that interact with AR as novel strategies to treat prostate cancer and even CRPC is desperately needed. 31833612 2020
Entrez Id: 5627
Gene Symbol: PROS1
PROS1
0.100 Biomarker disease BEFREE On multivariable analysis, higher PSA at castrate-resistant prostate cancer (4.67 vs. 4.4ng/mL, OR=0.57, P=0.02), shorter time from castrate-resistant prostate cancer to scan (7.9 vs. 14.6 months, OR=0.97, P=0.006) and higher PSA at scan (OR=2.91, P<0.0001) were significantly predictive of bone scan positivity. 31851457 2020
Entrez Id: 367
Gene Symbol: AR
AR
0.100 GeneticVariation disease BEFREE A novel small molecule targets androgen receptor and its splice variants in castration-resistant prostate cancer. 31554654 2020
Entrez Id: 5324
Gene Symbol: PLAG1
PLAG1
0.100 Biomarker disease BEFREE On multivariable analysis, higher PSA at castrate-resistant prostate cancer (4.67 vs. 4.4ng/mL, OR=0.57, P=0.02), shorter time from castrate-resistant prostate cancer to scan (7.9 vs. 14.6 months, OR=0.97, P=0.006) and higher PSA at scan (OR=2.91, P<0.0001) were significantly predictive of bone scan positivity. 31851457 2020