×
Entrez Id: 1112
Gene Symbol: FOXN3
FOXN3
0.010
Biomarker
disease
BEFREE
Forkhead box N3 (FOXN3 ) has been reported to be downregulated in numerous cancers, including laryngeal, oral squamous cell and hepatocellular carcinomas, and diffuse large B‑cell lymphoma .30483801 2019
×
Entrez Id: 904
Gene Symbol: CCNT1
CCNT1
0.010
AlteredExpression
disease
BEFREE
Aberrant expression of CDK9/cyclin T1 has been found in diffuse large B-cell lymphoma , and suggest that CDK9 seems to be a potential therapeutic target for diffuse large B-cell lymphoma .
31289198 2019
PDCD1LG2
0.010
GeneticVariation
disease
BEFREE
A high frequency of PD-L1/PD-L2 -involving genetic aberrations was observed in EBV-positive lymphomas [33 (22%) of 148 cases], including extranodal NK/T-cell lymphoma (ENKTL, 23%), aggressive NK-cell leukemia (57%), systemic EBV-positive T-cell lymphoproliferative disorder (17%) as well as EBV-positive diffuse large B-cell lymphoma (DLBCL, 19%) and peripheral T-cell lymphoma-not otherwise specified (15%).
30683910 2019
×
Entrez Id: 54625
Gene Symbol: PARP14
PARP14
0.010
Biomarker
disease
BEFREE
Subsequently, current literatures are presented to reveal the molecular mechanisms of PARP14 as a novel drug target for cancers (e.g., diffuse large B-cell lymphoma , multiple myeloma, prostate cancer, and hepatocellular carcinoma) and allergic inflammatory.
30890936 2019
×
Entrez Id: 7182
Gene Symbol: NR2C2
NR2C2
0.010
Biomarker
disease
BEFREE
TAK1 is a druggable kinase for diffuse large B-cell lymphoma .30907011 2019
×
Entrez Id: 5810
Gene Symbol: RAD1
RAD1
0.010
Biomarker
disease
BEFREE
Cytotoxicity of <sup>177</sup>Lu-NNV003 was measured in REC-1 (mantle cell lymphoma) and DOHH-2 (diffuse large B cell lymphoma ) cell lines.
31309259 2019
×
Entrez Id: 8405
Gene Symbol: SPOP
SPOP
0.010
Biomarker
disease
BEFREE
CRL3-SPOP ubiquitin ligase complex suppresses the growth of diffuse large B-cell lymphoma by negatively regulating the MyD88/NF-κB signaling.
31776466 2019
×
Entrez Id: 9353
Gene Symbol: SLIT2
SLIT2
0.010
PosttranslationalModification
disease
BEFREE
Low Expression and Promoter Hypermethylation of the Tumour Suppressor SLIT2 , are Associated with Adverse Patient Outcomes in Diffuse Large B Cell Lymphoma .
30739251 2019
×
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
0.010
AlteredExpression
disease
BEFREE
CDK6 overexpression resulted from microRNA‑320d downregulation promotes cell proliferation in diffuse large B‑cell lymphoma .31059102 2019
×
Entrez Id: 4854
Gene Symbol: NOTCH3
NOTCH3
0.010
AlteredExpression
disease
BEFREE
Expression of NOTCH3 exon 16 differentiates Diffuse Large B-cell Lymphoma into molecular subtypes and is associated with prognosis.
30674940 2019
SMAD5-AS1
0.010
Biomarker
disease
BEFREE
Lnc SMAD5-AS1 as ceRNA inhibit proliferation of diffuse large B cell lymphoma via Wnt/β-catenin pathway by sponging miR-135b-5p to elevate expression of APC.
30874550 2019
×
Entrez Id: 23028
Gene Symbol: KDM1A
KDM1A
0.010
Biomarker
disease
BEFREE
miR-101 regulates cell proliferation and apoptosis by targeting KDM1A in diffuse large B cell lymphoma .
31040714 2019
×
Entrez Id: 3902
Gene Symbol: LAG3
LAG3
0.010
Biomarker
disease
BEFREE
The immune checkpoint molecules PD-1, PD-L1, TIM-3 and LAG-3 in diffuse large B-cell lymphoma .
31007846 2019
×
Entrez Id: 133396
Gene Symbol: IL31RA
IL31RA
0.010
Biomarker
disease
BEFREE
CRL3 -SPOP ubiquitin ligase complex suppresses the growth of diffuse large B-cell lymphoma by negatively regulating the MyD88/NF-κB signaling.31776466 2019
×
Entrez Id: 2026
Gene Symbol: ENO2
ENO2
0.010
Biomarker
disease
BEFREE
NSE from diffuse large B-cell lymphoma cells regulates macrophage polarization.31191019 2019
×
Entrez Id: 8450
Gene Symbol: CUL4B
CUL4B
0.010
Biomarker
disease
BEFREE
CUL4B regulates autophagy via JNK signaling in diffuse large B-cell lymphoma .30612524 2019
×
Entrez Id: 286467
Gene Symbol: FIRRE
FIRRE
0.010
AlteredExpression
disease
BEFREE
LncRNA FIRRE is activated by MYC and promotes the development of diffuse large B-cell lymphoma via Wnt/β-catenin signaling pathway.
30739786 2019
×
Entrez Id: 6885
Gene Symbol: MAP3K7
MAP3K7
0.010
Biomarker
disease
BEFREE
TAK1 is a druggable kinase for diffuse large B-cell lymphoma .30907011 2019
×
Entrez Id: 4513
Gene Symbol: COX2
COX2
0.010
AlteredExpression
disease
BEFREE
Prognostic Value of Accumulative Expression of COX-2 and p53 in Small and Diffuse Large B Cell Lymphoma .
31187468 2019
×
Entrez Id: 5163
Gene Symbol: PDK1
PDK1
0.010
AlteredExpression
disease
BEFREE
Investigation of expressions of PDK1 , PLK1 and c-Myc in diffuse large B-cell lymphoma .
30912195 2019
×
Entrez Id: 115727
Gene Symbol: RASGRP4
RASGRP4
0.010
Biomarker
disease
BEFREE
The critical role of RasGRP4 in the growth of diffuse large B cell lymphoma .
31409422 2019
×
Entrez Id: 940
Gene Symbol: CD28
CD28
0.010
AlteredExpression
disease
BEFREE
B7-CD28 gene family expression is associated with prognostic and immunological characteristics of diffuse large B-cell lymphoma .
31195368 2019
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.010
AlteredExpression
disease
BEFREE
Prognostic Value of Accumulative Expression of COX-2 and p53 in Small and Diffuse Large B Cell Lymphoma .
31187468 2019
×
Entrez Id: 100616342
Gene Symbol: MIR4638
MIR4638
0.010
GeneticVariation
disease
BEFREE
Aberrant ERG expression associates with downregulation of miR-4638 -5p and selected genomic alterations in a subset of diffuse large B-cell lymphoma .
31237044 2019
×
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.010
AlteredExpression
disease
BEFREE
Prognostic value of pre-therapy C-reactive protein level in diffuse large B-cell lymphoma : a meta-analysis.
30033839 2019