Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		0.100 AlteredExpression disease BEFREE BCL2 overexpression in diffuse large B-cell lymphoma. 10350331 1999
Entrez Id: 604
Gene Symbol: BCL6
BCL6 		0.100 AlteredExpression disease BEFREE Bcl-6 and Bcl-2 protein expression in diffuse large B-cell lymphoma and follicular lymphoma: correlation with 3q27 and 18q21 chromosomal abnormalities. 10414499 1999
Entrez Id: 896
Gene Symbol: CCND3
CCND3 		0.040 Biomarker disease BEFREE Cyclin D3 overexpression and p16INK4A/pRb aberrations were mutually exclusive, supporting an oncogenic role for cyclin D3 in DLCL. p16INK4A inactivation, cyclin D3 overexpression, or aberrant pRb expression was identified in 18 of 34 DLCLs (53%). 10803523 2000
Entrez Id: 604
Gene Symbol: BCL6
BCL6 		0.100 AlteredExpression disease BEFREE Bcl-6 mRNA and protein are frequently expressed in the transformed counterparts of the germinal center B-cells, diffuse large B-cell lymphoma and follicular lymphoma, irrespective of the gene rearrangements. 11353050 2001
Entrez Id: 472
Gene Symbol: ATM
ATM 		0.040 GeneticVariation disease BEFREE ATM mutations are associated with inactivation of the ARF-TP53 tumor suppressor pathway in diffuse large B-cell lymphoma. 12149228 2002
Entrez Id: 8915
Gene Symbol: BCL10
BCL10 		0.040 GeneticVariation disease BEFREE Bcl 10 rearrangement was detected in 20 of 137 (14.6%) samples of DLBL. 12153171 2002
Entrez Id: 257144
Gene Symbol: GCSAM
GCSAM 		0.030 Biomarker disease BEFREE HGAL is a novel interleukin-4-inducible gene that strongly predicts survival in diffuse large B-cell lymphoma. 12509382 2003
Entrez Id: 238
Gene Symbol: ALK
ALK 		0.100 Biomarker disease BEFREE ALK-positive diffuse large B-cell lymphoma is associated with Clathrin-ALK rearrangements: report of 6 cases. 12763927 2003
Entrez Id: 330
Gene Symbol: BIRC3
BIRC3 		0.040 GeneticVariation disease BEFREE API2-MALT1 fusion genes were detected in seven cases (15%) of MALT lymphoma and one case (8%) of diffuse large B-cell lymphoma. 14681324 2003
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.100 GeneticVariation disease BEFREE Interleukin-10 gene promoter polymorphisms influence the clinical outcome of diffuse large B-cell lymphoma. 14701701 2004
Entrez Id: 238
Gene Symbol: ALK
ALK 		0.100 Biomarker disease BEFREE ALK-positive diffuse large B-cell lymphoma of the stomach associated with a clathrin-ALK rearrangement. 15492998 2004
Entrez Id: 27086
Gene Symbol: FOXP1
FOXP1 		0.100 AlteredExpression disease BEFREE FOXP1, a gene highly expressed in a subset of diffuse large B-cell lymphoma, is recurrently targeted by genomic aberrations. 15944719 2005
Entrez Id: 83666
Gene Symbol: PARP9
PARP9 		0.020 Biomarker disease BEFREE BAL1 (B-aggressive lymphoma 1) was originally identified as a risk-related gene in diffuse large B-cell lymphoma. 16061477 2005
Entrez Id: 2214
Gene Symbol: FCGR3A
FCGR3A 		0.060 GeneticVariation disease BEFREE FCGR3A gene polymorphisms may correlate with response to frontline R-CHOP therapy for diffuse large B-cell lymphoma. 16609067 2006
Entrez Id: 27086
Gene Symbol: FOXP1
FOXP1 		0.100 AlteredExpression disease BEFREE Forkhead box protein P1 expression in mucosa-associated lymphoid tissue lymphomas predicts poor prognosis and transformation to diffuse large B-cell lymphoma. 16636337 2006
Entrez Id: 355
Gene Symbol: FAS
FAS 		0.020 AlteredExpression disease BEFREE FAS death domain deletions and cellular FADD-like interleukin 1beta converting enzyme inhibitory protein (long) overexpression: alternative mechanisms for deregulating the extrinsic apoptotic pathway in diffuse large B-cell lymphoma subtypes. 16740746 2006
Entrez Id: 8915
Gene Symbol: BCL10
BCL10 		0.040 AlteredExpression disease BEFREE BCL10 gene amplification associated with strong nuclear BCL10 expression in a diffuse large B cell lymphoma with IGH-BCL2 fusion. 16785131 2006
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		0.100 AlteredExpression disease BEFREE Bcl-2 gene expression as a predictor of outcome in diffuse large B-cell lymphoma. 16796775 2006
Entrez Id: 238
Gene Symbol: ALK
ALK 		0.100 Biomarker disease BEFREE ALK-positive diffuse large B-cell lymphoma: report of four cases and review of the literature. 17277765 2007
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2 		0.040 GeneticVariation disease BEFREE BCRP gene polymorphisms are associated with susceptibility and survival of diffuse large B-cell lymphoma. 17494054 2007
Entrez Id: 238
Gene Symbol: ALK
ALK 		0.100 Biomarker disease BEFREE Anaplastic lymphoma kinase-positive diffuse large B-cell lymphoma with a complex karyotype and cryptic 3' ALK gene insertion to chromosome 4 q22-24. 17509395 2007
Entrez Id: 1649
Gene Symbol: DDIT3
DDIT3 		0.100 AlteredExpression disease BEFREE CHOP-R therapy overcomes the adverse prognostic influence of BCL-2 expression in diffuse large B-cell lymphoma. 17577773 2007
Entrez Id: 2214
Gene Symbol: FCGR3A
FCGR3A 		0.060 GeneticVariation disease BEFREE FCgammaRIIIA and FCgammaRIIA polymorphisms are not associated with response to rituximab and CHOP in patients with diffuse large B-cell lymphoma. 17606457 2007
Entrez Id: 6850
Gene Symbol: SYK
SYK 		0.030 Biomarker disease BEFREE SYK-dependent tonic B-cell receptor signaling is a rational treatment target in diffuse large B-cell lymphoma. 18006696 2008
Entrez Id: 10017
Gene Symbol: BCL2L10
BCL2L10 		0.010 Biomarker disease BEFREE Bcl-B immunostaining was also present in normal germinal center centroblasts and centrocytes and in approximately half of diffuse large B-cell lymphoma (n = 48) specimens, whereas follicular lymphomas (n = 57) did not contain Bcl-B. 18483366 2008