Gene: MSH2 ×
Source: INFERRED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 GeneticVariation disease CLINVAR Microsatellite Instability Is Associated With the Presence of Lynch Syndrome Pan-Cancer. 30376427 2019
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 CausalMutation disease CLINVAR Outcomes of disease-specific next-generation sequencing gene panel testing in adolescents and young adults with colorectal cancer. 31101557 2019
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 CausalMutation disease CLINVAR Screening for germline mutations in mismatch repair genes in patients with Lynch syndrome by next generation sequencing. 28932927 2018
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 CausalMutation disease CLINVAR Germline MLH1, MSH2 and MSH6 variants in Brazilian patients with colorectal cancer and clinical features suggestive of Lynch Syndrome. 29575718 2018
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 GeneticVariation disease CLINVAR Exome sequencing covers >98% of mutations identified on targeted next generation sequencing panels. 28152038 2017
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 CausalMutation disease CLINVAR Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer. 27978560 2017
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 CausalMutation disease CLINVAR Thyroid cancer in a patient with Lynch syndrome - case report and literature review. 28769567 2017
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 CausalMutation disease CLINVAR Spectrum of mismatch repair gene mutations and clinical presentation of Hispanic individuals with Lynch syndrome. 28449805 2017
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 GeneticVariation disease CLINVAR Multigene Panel Testing Provides a New Perspective on Lynch Syndrome. 28514183 2017
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 CausalMutation disease CLINVAR MLH1 Ile219Val Polymorphism in Argentinean Families with Suspected Lynch Syndrome. 27606285 2016
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 CausalMutation disease CLINVAR Frequent mismatch-repair defects link prostate cancer to Lynch syndrome. 27013479 2016
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 CausalMutation disease CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312 2016
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 CausalMutation disease CLINVAR Oligonucleotide-directed mutagenesis screen to identify pathogenic Lynch syndrome-associated MSH2 DNA mismatch repair gene variants. 26951660 2016
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 CausalMutation disease CLINVAR Lynch syndrome mutation spectrum in New South Wales, Australia, including 55 novel mutations. 27064304 2016
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 CausalMutation disease CLINVAR Genetic diagnosis of high-penetrance susceptibility for colorectal cancer (CRC) is achievable for a high proportion of familial CRC by exome sequencing. 25559809 2015
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 CausalMutation disease CLINVAR Lynch-like syndrome: characterization and comparison with EPCAM deletion carriers. 25110875 2015
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 CausalMutation disease CLINVAR Genetic features of Lynch syndrome in the Israeli population. 25430799 2015
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 CausalMutation disease CLINVAR Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome. 25980754 2015
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 GeneticVariation disease CLINVAR Genetic features of Lynch syndrome in the Israeli population. 25430799 2015
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 CausalMutation disease CLINVAR Mismatch repair deficient-crypts in non-neoplastic colonic mucosa in Lynch syndrome: insights from an illustrative case. 25173403 2015
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 GeneticVariation disease CLINVAR Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome. 25980754 2015
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 CausalMutation disease CLINVAR Clinical and Molecular Characterization of Brazilian Patients Suspected to Have Lynch Syndrome. 26437257 2015
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 CausalMutation disease CLINVAR Lynch Syndrome in patients with clear cell and endometrioid cancers of the ovary. 25093288 2014
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 CausalMutation disease CLINVAR Muir-Torre syndrome: case report and molecular characterization. 24474082 2014
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		1.000 CausalMutation disease CLINVAR Colon and endometrial cancers with mismatch repair deficiency can arise from somatic, rather than germline, mutations. 25194673 2014