Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5241
Gene Symbol: PGR
PGR 		0.310 Biomarker disease BEFREE All secretory meningiomas were positive for EMA and PR and negative for S100, and this pattern exhibited a rostrocaudal gradient. 30503291 2019
Entrez Id: 4771
Gene Symbol: NF2
NF2 		0.310 Biomarker disease CTD_human Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations. 23334667 2013
Entrez Id: 5241
Gene Symbol: PGR
PGR 		0.310 Biomarker disease CTD_human Regression of multiple intracranial meningiomas after cessation of long-term progesterone agonist therapy. 19731987 2010
Entrez Id: 5241
Gene Symbol: PGR
PGR 		0.310 Biomarker disease CTD_human Toward understanding recurrent meningioma: the potential role of lysosomal cysteine proteases and their inhibitors. 19747051 2010
Entrez Id: 4771
Gene Symbol: NF2
NF2 		0.310 Biomarker disease BEFREE Our results may indicate a molecular, besides morphologic, similarity between secretory and meningothelial meningiomas: the almost constant merlin immunohistochemical expression in our series gives evidence for a possible NF2 gene-independent pathogenesis in secretory meningiomas. 17721284 2007
Entrez Id: 5241
Gene Symbol: PGR
PGR 		0.310 Biomarker disease CTD_human Sphenoid wing meningioma progression after placement of a subcutaneous progesterone agonist contraceptive implant. 8008172 1994
Entrez Id: 8314
Gene Symbol: BAP1
BAP1 		0.300 Biomarker disease CTD_human Inference on germline BAP1 mutations and asbestos exposure from the analysis of familial and sporadic mesothelioma in a high-risk area. 25231345 2015
Entrez Id: 6608
Gene Symbol: SMO
SMO 		0.300 Biomarker disease CTD_human Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations. 23334667 2013
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		0.300 Biomarker disease CTD_human Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations. 23334667 2013
Entrez Id: 8028
Gene Symbol: MLLT10
MLLT10 		0.300 Biomarker disease CTD_human Common variation at 10p12.31 near MLLT10 influences meningioma risk. 21804547 2011
Entrez Id: 3280
Gene Symbol: HES1
HES1 		0.300 Biomarker disease CTD_human Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres. 21127729 2010
Entrez Id: 1476
Gene Symbol: CSTB
CSTB 		0.300 Biomarker disease CTD_human Toward understanding recurrent meningioma: the potential role of lysosomal cysteine proteases and their inhibitors. 19747051 2010
Entrez Id: 1471
Gene Symbol: CST3
CST3 		0.300 Biomarker disease CTD_human Toward understanding recurrent meningioma: the potential role of lysosomal cysteine proteases and their inhibitors. 19747051 2010
Entrez Id: 1514
Gene Symbol: CTSL
CTSL 		0.300 Biomarker disease CTD_human Toward understanding recurrent meningioma: the potential role of lysosomal cysteine proteases and their inhibitors. 19747051 2010
Entrez Id: 210
Gene Symbol: ALAD
ALAD 		0.300 Biomarker disease CTD_human Delta-aminolevulinic acid dehydratase polymorphism and risk of brain tumors in adults. 16140629 2005
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.300 Biomarker disease CTD_human A novel germline mutation of PTEN associated with brain tumours of multiple lineages. 12085208 2002
Entrez Id: 9314
Gene Symbol: KLF4
KLF4 		0.030 Biomarker disease BEFREE KLF4, a transcription factor known for its role in stemness maintenance, was identified as one of the most frequently mutated genes in the benign secretory meningioma. 28651379 2017
Entrez Id: 9314
Gene Symbol: KLF4
KLF4 		0.030 GeneticVariation disease BEFREE To our knowledge, these are the first two cases reported of the simultaneous occurrence of secretory meningiomas with mutation of KLF4 in collision with a glioblastoma and an anaplastic astrocytoma, respectively. 26227255 2016
Entrez Id: 9314
Gene Symbol: KLF4
KLF4 		0.030 GeneticVariation disease BEFREE While KLF4 mutations were exclusively seen in secretory meningiomas, TRAF7 mutations were also observed in 7/89 (8 %) of non-secretory meningiomas. 23404370 2013
Entrez Id: 84231
Gene Symbol: TRAF7
TRAF7 		0.020 GeneticVariation disease BEFREE KLF4- and TRAF7-mutated tumors were predominantly secretory meningiomas. 31177425 2019
Entrez Id: 84231
Gene Symbol: TRAF7
TRAF7 		0.020 GeneticVariation disease BEFREE While KLF4 mutations were exclusively seen in secretory meningiomas, TRAF7 mutations were also observed in 7/89 (8 %) of non-secretory meningiomas. 23404370 2013
Entrez Id: 9368
Gene Symbol: SLC9A3R1
SLC9A3R1 		0.010 GeneticVariation disease BEFREE In a meningioma series from 83 patients, NHERF1 revealed microlumens in 87.5% of the chordoid meningioma (<i>n</i> = 25) and meningioma with chordoid component (<i>n</i> = 7) cases, and in 100% of the secretory meningioma cases (<i>n</i> = 12). 29983887 2018
Entrez Id: 2335
Gene Symbol: FN1
FN1 		0.010 AlteredExpression disease BEFREE Secretory meningiomas showed high expressions of fibronectin and galectin-3. 22995327 2013