×
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1
0.210
AlteredExpression
disease
BEFREE
Furthermore, Ala deceased the density of cardiac fibrosis , as assessed by Masson and Sirius red staining; reduced expression of fibrotic proteins, including connective tissue growth factor, collagen I (COL1A1 ) and matrix metalloproteinase 9, was also observed.
31059021 2019
×
Entrez Id: 177
Gene Symbol: AGER
AGER
0.210
Biomarker
disease
BEFREE
It has been reported that receptor for advanced glycation end-products (RAGE ) plays a significant role in cardiac fibrosis .
27372036 2016
×
Entrez Id: 177
Gene Symbol: AGER
AGER
0.210
Therapeutic
disease
RGD
Calcitriol modulates receptor for advanced glycation end products (RAGE) in diabetic hearts.
24630381 2014
×
Entrez Id: 2697
Gene Symbol: GJA1
GJA1
0.210
Biomarker
disease
RGD
[Effects of glutamine induced heat shock protein 70 overexpression on atrial fibrosis and connexin 43 remodeling in isoprenaline-treated rats].
23906405 2013
×
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1
0.210
Biomarker
disease
RGD
MiR-133a regulates collagen 1A1: potential role of miR-133a in myocardial fibrosis in angiotensin II-dependent hypertension.
21769867 2012
×
Entrez Id: 177
Gene Symbol: AGER
AGER
0.210
Biomarker
disease
RGD
Angiotensin II type 1 receptor blocker attenuates diabetes-induced atrial structural remodeling.
21802905 2011
×
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1
0.210
Therapeutic
disease
RGD
A synthetic peptide from transforming growth factor-beta1 type III receptor prevents myocardial fibrosis in spontaneously hypertensive rats.
19019833 2009
×
Entrez Id: 2693
Gene Symbol: GHSR
GHSR
0.210
Biomarker
disease
RGD
Cardioprotective effects of ghrelin and des-octanoyl ghrelin on myocardial injury induced by isoproterenol in rats.
16626506 2006
×
Entrez Id: 9927
Gene Symbol: MFN2
MFN2
0.200
Biomarker
disease
RGD
MicroRNA-214 Mediates Isoproterenol-induced Proliferation and Collagen Synthesis in Cardiac Fibroblasts.
26692091 2015
×
Entrez Id: 144100
Gene Symbol: PLEKHA7
PLEKHA7
0.200
Biomarker
disease
RGD
Mutation of Plekha7 attenuates salt-sensitive hypertension in the rat.
25136115 2014
×
Entrez Id: 1756
Gene Symbol: DMD
DMD
0.200
Biomarker
disease
RGD
Characterization of dystrophin deficient rats: a new model for Duchenne muscular dystrophy.
25310701 2014
×
Entrez Id: 4792
Gene Symbol: NFKBIA
NFKBIA
0.200
Therapeutic
disease
RGD
Whole grape intake impacts cardiac peroxisome proliferator-activated receptor and nuclear factor kappaB activity and cytokine expression in rats with diastolic dysfunction.
20231522 2010
×
Entrez Id: 51738
Gene Symbol: GHRL
GHRL
0.200
ModifyingMutation
disease
RGD
Cardioprotective effects of ghrelin and des-octanoyl ghrelin on myocardial injury induced by isoproterenol in rats.
16626506 2006
×
Entrez Id: 2200
Gene Symbol: FBN1
FBN1
0.200
Biomarker
disease
RGD
Enhanced expression of fibrillin-1, a constituent of the myocardial extracellular matrix in fibrosis.
15849235 2005
×
Entrez Id: 4316
Gene Symbol: MMP7
MMP7
0.200
Biomarker
disease
RGD
Fibrosis of the left atria during progression of heart failure is associated with increased matrix metalloproteinases in the rat.
12875773 2003
×
Entrez Id: 183
Gene Symbol: AGT
AGT
0.100
Biomarker
disease
BEFREE
Next, we investigated the effects of lncRNA FAF on angiotensinogen II (Ang II)-induced cardiac fibrosis in neonatal rat CFs and explored the mechanism underlying these effects.
31708099 2020
×
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
0.100
Biomarker
disease
BEFREE
Conclusions Gal-3 and ST2 are considered as a reflection of cardiac fibrosis and remodeling.
31622239 2020
×
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
0.100
AlteredExpression
disease
BEFREE
Linaclotide ameliorated renal inflammation and fibrosis and cardiac fibrosis , as well as decreased the expression of collagen I, transforming growth factor-β, galectin-3 (Gal-3 ) and ST2 genes.
31411705 2020
×
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
0.100
Biomarker
disease
BEFREE
It remains unclear whether Gal-3 interacts with K<sub>Ca</sub>3.1 leading to cardiac fibrosis in the setting of βAR activation.
31838908 2020
×
Entrez Id: 183
Gene Symbol: AGT
AGT
0.100
Biomarker
disease
BEFREE
Steroidogenic acute regulatory protein/aldosterone synthase mediates angiotensin II -induced cardiac fibrosis and hypertrophy.
31820314 2020
×
Entrez Id: 183
Gene Symbol: AGT
AGT
0.100
Biomarker
disease
BEFREE
Opposite Effects of Moderate and Extreme Cx43 Deficiency in Conditional Cx43-Deficient Mice on Angiotensin II -Induced Cardiac Fibrosis .
31652649 2019
×
Entrez Id: 183
Gene Symbol: AGT
AGT
0.100
Biomarker
disease
BEFREE
Endothelial-specific deletion of Ets-1 attenuates Angiotensin II -induced cardiac fibrosis via suppression of endothelial-to-mesenchymal transition.
30670148 2019
×
Entrez Id: 183
Gene Symbol: AGT
AGT
0.100
Biomarker
disease
BEFREE
Echocardiographic analysis, Sirius Red staining and immunofluorescence staining were performed to investigate the function of circHIPK3 in angiotensin II (Ang II) induced cardiac fibrosis in vivo.
30967276 2019
×
Entrez Id: 183
Gene Symbol: AGT
AGT
0.100
Biomarker
disease
BEFREE
Protocatechuic acid attenuates angiotensin II -induced cardiac fibrosis in cardiac fibroblasts through inhibiting the NOX4/ROS/p38 signaling pathway.
31318113 2019
×
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
0.100
Biomarker
disease
BEFREE
We assessed the predictive ability of circulating biomarkers involved in collagen synthesis (procollagen type I N-terminal propeptide [PINP], and procollagen type III N-terminal propeptide [PIIINP], collagen degradation (c-terminal telopeptide of collagen type I [CTx] and mediators of cardiac fibrosis (Galectin-3 and soluble suppression of tumorigenicity 2 protein or sST2) as prognosis markers in 182 subjects with chronic heart failure (HF).
30179616 2019