Source: CURATED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 Biomarker group CTD_human p53 mutants cooperate with HIF-1 in transcriptional regulation of extracellular matrix components to promote tumor progression. 30381462 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 Biomarker group CTD_human The oncoprotein HBXIP modulates the feedback loop of MDM2/p53 to enhance the growth of breast cancer. 26229107 2015
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 Biomarker group CTD_human Genomic landscape of cutaneous T cell lymphoma. 26192916 2015
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 Biomarker group CTD_human Exquisite sensitivity of TP53 mutant and basal breast cancers to a dose-dense epirubicin-cyclophosphamide regimen. 17388661 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 Biomarker group CTD_human Evaluation of the prognostic and predictive value of p53 and Bcl-2 in breast cancer patients participating in a randomized study with dose-dense sequential adjuvant chemotherapy. 16968874 2006
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 Biomarker group CTD_human Worse survival for TP53 (p53)-mutated breast cancer patients receiving adjuvant CMF. 15802278 2005
Entrez Id: 4312
Gene Symbol: MMP1
MMP1 		0.600 Biomarker group CTD_human Matrix metalloproteinase Mmp-1a is dispensable for normal growth and fertility in mice and promotes lung cancer progression by modulating inflammatory responses. 23548910 2013
Entrez Id: 4214
Gene Symbol: MAP3K1
MAP3K1 		0.530 Biomarker group CTD_human Genome-wide association study identifies novel breast cancer susceptibility loci. 17529967 2007
Entrez Id: 4214
Gene Symbol: MAP3K1
MAP3K1 		0.530 CausalMutation group CGI
Entrez Id: 167465
Gene Symbol: ZNF366
ZNF366 		0.510 Biomarker group CTD_human DC-SCRIPT: nuclear receptor modulation and prognostic significance in primary breast cancer. 20008677 2010
Entrez Id: 2475
Gene Symbol: MTOR
MTOR 		0.500 Biomarker group CTD_human Identification of recurrent fusion genes across multiple cancer types. 30705370 2019
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3 		0.500 Biomarker group CTD_human A ROR1-HER3-lncRNA signalling axis modulates the Hippo-YAP pathway to regulate bone metastasis. 28114269 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.500 Biomarker group CTD_human A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer. 28825726 2017
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.500 Biomarker group CTD_human A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer. 28825726 2017
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.500 Biomarker group CTD_human A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer. 28825726 2017
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		0.500 Biomarker group CTD_human Discovery at the interface: Toward novel anti-proliferative agents targeting human estrogen receptor/S100 interactions. 27580430 2016
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.500 Biomarker group CTD_human Breast cancer 1 (BRCA1)-deficient embryos develop normally but are more susceptible to ethanol-initiated DNA damage and embryopathies. 26629949 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.500 Therapeutic group CTD_human Prognostic Significance of VEGFC and VEGFR1 mRNA Expression According to HER2 Status in Breast Cancer: A Study of Primary Tumors from Patients with High-risk Early Breast Cancer Participating in a Randomized Hellenic Cooperative Oncology Group Trial. 26124351 2015
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.500 Biomarker group CTD_human These results validate the concept of using pigs as a model to study BRCA1 defects in breast cancer and establish the first porcine breast tumor cell line. 26379698 2015
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.500 Biomarker group CTD_human Prognostic Significance of VEGFC and VEGFR1 mRNA Expression According to HER2 Status in Breast Cancer: A Study of Primary Tumors from Patients with High-risk Early Breast Cancer Participating in a Randomized Hellenic Cooperative Oncology Group Trial. 26124351 2015
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		0.500 Biomarker group CTD_human Comparison of targeted next-generation sequencing and Sanger sequencing for the detection of PIK3CA mutations in breast cancer. 26587011 2015
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		0.500 Biomarker group CTD_human Combined deletion of Pten and p53 in mammary epithelium accelerates triple-negative breast cancer with dependency on eEF2K. 25330770 2014
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.500 Therapeutic group CTD_human CDK4/6 inhibition provides a potent adjunct to Her2-targeted therapies in preclinical breast cancer models. 25221644 2014
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		0.500 Biomarker group CTD_human Molecular profiling of single circulating tumor cells with diagnostic intention. 25358515 2014
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		0.500 Biomarker group CTD_human Genomic high-resolution profiling of single CKpos/CD45neg flow-sorting purified circulating tumor cells from patients with metastatic breast cancer. 25267515 2014