Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4 		0.300 Therapeutic phenotype CTD_human Phosphorylation of hepatic farnesoid X receptor by FGF19 signaling-activated Src maintains cholesterol levels and protects from atherosclerosis. 30996006 2019
Entrez Id: 63036
Gene Symbol: CELA2A
CELA2A 		0.300 Biomarker phenotype CTD_human CELA2A mutations predispose to early-onset atherosclerosis and metabolic syndrome and affect plasma insulin and platelet activation. 31358993 2019
Entrez Id: 10155
Gene Symbol: TRIM28
TRIM28 		0.300 Biomarker phenotype CTD_human Knockdown of TRIM28 inhibits PDGF-BB-induced vascular smooth muscle cell proliferation and migration. 31351049 2019
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker phenotype CTD_human Using the Apolipoprotein E Knock-Out Mouse Model to Define Atherosclerotic Plaque Changes Induced by Low Dose Arsenic. 30376133 2018
Entrez Id: 3949
Gene Symbol: LDLR
LDLR 		0.300 Biomarker phenotype CTD_human Pharmacological inhibition of protein tyrosine phosphatase 1B protects against atherosclerotic plaque formation in the LDLR-/- mouse model of atherosclerosis. 28899902 2017
Entrez Id: 3949
Gene Symbol: LDLR
LDLR 		0.300 Therapeutic phenotype CTD_human Pharmacological inhibition of protein tyrosine phosphatase 1B protects against atherosclerotic plaque formation in the LDLR-/- mouse model of atherosclerosis. 28899902 2017
Entrez Id: 5819
Gene Symbol: NECTIN2
NECTIN2 		0.300 Biomarker phenotype CTD_human Poliovirus Receptor-Related 2: A Cholesterol-Responsive Gene Affecting Atherosclerosis Development by Modulating Leukocyte Migration. 28062492 2017
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker phenotype CTD_human Sinigrin attenuates the progression of atherosclerosis in ApoE-/- mice fed a high-cholesterol diet potentially by inhibiting VCAM-1 expression. 28483571 2017
Entrez Id: 1071
Gene Symbol: CETP
CETP 		0.300 Therapeutic phenotype CTD_human A novel atheroprotective role of MF59-like adjuvant when co-administered with CETP vaccine in rabbit model of atherosclerosis. 28096968 2016
Entrez Id: 602
Gene Symbol: BCL3
BCL3 		0.300 Biomarker phenotype CTD_human An integrated genomic-transcriptomic approach supports a role for the proto-oncogene BCL3 in atherosclerosis. 25374339 2015
Entrez Id: 5444
Gene Symbol: PON1
PON1 		0.300 Biomarker phenotype CTD_human Association between Paraoxonase 1 (PON1) Polymorphisms and the Risk of Acute Coronary Syndrome in a North African Population. 26241956 2015
Entrez Id: 3949
Gene Symbol: LDLR
LDLR 		0.300 Therapeutic phenotype CTD_human Bisphenol A exposure induces metabolic disorders and enhances atherosclerosis in hyperlipidemic rabbits. 25619500 2015
Entrez Id: 5444
Gene Symbol: PON1
PON1 		0.300 Therapeutic phenotype CTD_human Association between Paraoxonase 1 (PON1) Polymorphisms and the Risk of Acute Coronary Syndrome in a North African Population. 26241956 2015
Entrez Id: 3949
Gene Symbol: LDLR
LDLR 		0.300 Biomarker phenotype CTD_human Bisphenol A exposure induces metabolic disorders and enhances atherosclerosis in hyperlipidemic rabbits. 25619500 2015
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker phenotype CTD_human Pulmonary exposure to particles from diesel exhaust, urban dust or single-walled carbon nanotubes and oxidatively damaged DNA and vascular function in apoE(-/-) mice. 23148895 2014
Entrez Id: 6348
Gene Symbol: CCL3
CCL3 		0.300 Biomarker phenotype CTD_human 27-Hydroxycholesterol and 7alpha-hydroxycholesterol trigger a sequence of events leading to migration of CCR5-expressing Th1 lymphocytes. 24370436 2014
Entrez Id: 3269
Gene Symbol: HRH1
HRH1 		0.300 Biomarker phenotype CTD_human Chronic ingestion of H1-antihistamines increase progression of atherosclerosis in apolipoprotein E-/- mice. 25020133 2014
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker phenotype CTD_human Chronic ingestion of H1-antihistamines increase progression of atherosclerosis in apolipoprotein E-/- mice. 25020133 2014
Entrez Id: 6351
Gene Symbol: CCL4
CCL4 		0.300 Biomarker phenotype CTD_human 27-Hydroxycholesterol and 7alpha-hydroxycholesterol trigger a sequence of events leading to migration of CCR5-expressing Th1 lymphocytes. 24370436 2014
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker phenotype CTD_human Diesel exhaust particulate increases the size and complexity of lesions in atherosclerotic mice. 24330719 2013
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker phenotype CTD_human Dietary quercetin attenuates oxidant-induced endothelial dysfunction and atherosclerosis in apolipoprotein E knockout mice fed a high-fat diet: a critical role for heme oxygenase-1. 24017971 2013
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker phenotype CTD_human Cigarette smoke induces molecular responses in respiratory tissues of ApoE(-/-) mice that are progressively deactivated upon cessation. 24096154 2013
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker phenotype CTD_human Inhibitory effects of myricitrin on oxidative stress-induced endothelial damage and early atherosclerosis in ApoE-/- mice. 23639522 2013
Entrez Id: 196
Gene Symbol: AHR
AHR 		0.300 Biomarker phenotype CTD_human Inherent and benzo[a]pyrene-induced differential aryl hydrocarbon receptor signaling greatly affects life span, atherosclerosis, cardiac gene expression, and body and heart growth in mice. 22228805 2012
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker phenotype CTD_human Inherent and benzo[a]pyrene-induced differential aryl hydrocarbon receptor signaling greatly affects life span, atherosclerosis, cardiac gene expression, and body and heart growth in mice. 22228805 2012