×
Entrez Id:
4868
Gene Symbol:
NPHS1
NPHS1
0.330
GeneticVariation
disease
BEFREE
Nineteen patients (53%), especially those with minimal change nephrotic syndrome (MCNS ) at initial biopsy (p < 0.002), entered complete remission with CSA monotherapy, including one patient with compound heterozygous NPHS1 and dominant ACTN4 mutation, respectively.
25903641
2015
×
Entrez Id:
4868
Gene Symbol:
NPHS1
NPHS1
0.330
GeneticVariation
disease
BEFREE
Patients with a single mutation in NPHS1 received a diagnosis before those with potentially nongenetic NS and had a good response to therapies.Renal function was normal in all cases.
19406966
2009
×
Entrez Id:
4868
Gene Symbol:
NPHS1
NPHS1
0.330
Biomarker
disease
CTD_human
Decreased tyrosine phosphorylation of nephrin in rat and human nephrosis.
18256598
2008
×
Entrez Id:
4868
Gene Symbol:
NPHS1
NPHS1
0.330
GeneticVariation
disease
BEFREE
The analysis of NPHS1 revealed no specific MCNS -associated mutation.
15086927
2004
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
0.100
GeneticVariation
disease
BEFREE
Angiotensin-converting enzyme genotype is not a significant genetic risk factor for idiopathic nephrotic syndrome in Croatian children.
25997642
2015
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
0.100
Biomarker
disease
BEFREE
Association of ACE and MDR1 Gene Polymorphisms with Steroid Resistance in Children with Idiopathic Nephrotic Syndrome .
26154535
2015
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
0.100
GeneticVariation
disease
BEFREE
We analyzed the association of ACE gene I/D polymorphism with the clinical presentation of minimal change nephrotic syndrome (MCNS ) in a Turkish child population.
22017506
2012
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
0.100
GeneticVariation
disease
BEFREE
An assessment of the association between ACE I /D gene polymorphism and idiopathic nephrotic syndrome (INS) susceptibility in children is still controversial.
21946394
2011
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
0.100
GeneticVariation
disease
BEFREE
ACE I /D gene polymorphism can't predict the steroid responsiveness in Asian children with idiopathic nephrotic syndrome : a meta-analysis.
21611163
2011
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
0.100
GeneticVariation
disease
BEFREE
Effect of angiotensin-converting enzyme gene insertion/deletion polymorphism on steroid resistance in Egyptian children with idiopathic nephrotic syndrome .
20418353
2010
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
0.100
GeneticVariation
disease
BEFREE
Angiotensin-converting enzyme gene polymorphism in children with idiopathic nephrotic syndrome .
16645262
2006
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
0.100
GeneticVariation
disease
BEFREE
Angiotensin converting enzyme gene polymorphisms do not predict the course of idiopathic nephrotic syndrome in Swiss children.
17199794
2006
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
0.100
GeneticVariation
disease
BEFREE
In the entire group of children with NS , the frequencies of the II, ID, and DD genotypes of ACE gene were 13.7%, 38.3% and 48%, respectively.
16208534
2005
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
0.100
GeneticVariation
disease
BEFREE
Angiotensin-converting enzyme gene polymorphism in patients with minimal-change nephrotic syndrome and focal segmental glomerulosclerosis.
9434071
1997
×
Entrez Id:
5243
Gene Symbol:
ABCB1
ABCB1
0.050
GeneticVariation
disease
BEFREE
A PRISMA-compliant meta-analysis of MDR1 polymorphisms and idiopathic nephrotic syndrome : Susceptibility and steroid responsiveness.
28614261
2017
×
Entrez Id:
5243
Gene Symbol:
ABCB1
ABCB1
0.050
GeneticVariation
disease
BEFREE
Erratum: A PRISMA-compliant meta-analysis of MDR1 polymorphisms and idiopathic nephrotic syndrome : Susceptibility and steroid responsiveness: Erratum.
31305689
2017
×
Entrez Id:
7827
Gene Symbol:
NPHS2
NPHS2
0.050
GeneticVariation
disease
BEFREE
Report of novel genetic variation in NPHS2 gene associated with idiopathic nephrotic syndrome in South Indian children.
26820844
2017
×
Entrez Id:
5243
Gene Symbol:
ABCB1
ABCB1
0.050
GeneticVariation
disease
BEFREE
ABCB1 polymorphisms and steroid treatment in children with idiopathic nephrotic syndrome .
27719329
2017
×
Entrez Id:
5243
Gene Symbol:
ABCB1
ABCB1
0.050
GeneticVariation
disease
BEFREE
Association of ACE and MDR1 Gene Polymorphisms with Steroid Resistance in Children with Idiopathic Nephrotic Syndrome .
26154535
2015
×
Entrez Id:
5243
Gene Symbol:
ABCB1
ABCB1
0.050
GeneticVariation
disease
BEFREE
MDR1 polymorphisms and idiopathic nephrotic syndrome in Slovak children: preliminary results.
25559283
2015
×
Entrez Id:
7827
Gene Symbol:
NPHS2
NPHS2
0.050
GeneticVariation
disease
BEFREE
Mutational analysis of the NPHS2 gene in Czech patients with idiopathic nephrotic syndrome .
22578956
2012
×
Entrez Id:
7827
Gene Symbol:
NPHS2
NPHS2
0.050
GeneticVariation
disease
BEFREE
We reviewed the clinical features of 40 patients with NS associated with heterozygous mutations or variants in NPHS1 (n = 7) or NPHS2 (n = 33).
19406966
2009
×
Entrez Id:
7827
Gene Symbol:
NPHS2
NPHS2
0.050
GeneticVariation
disease
BEFREE
NPHS2 (podicin) mutations in Turkish children with idiopathic nephrotic syndrome .
17899208
2007
×
Entrez Id:
7827
Gene Symbol:
NPHS2
NPHS2
0.050
GeneticVariation
disease
BEFREE
Mapping a gene (SRN1 ) to chromosome 1q25-q31 in idiopathic nephrotic syndrome confirms a distinct entity of autosomal recessive nephrosis.
8589695
1995
×
Entrez Id:
3569
Gene Symbol:
IL6
IL6
0.040
AlteredExpression
disease
BEFREE
Extensive workups were done, and there were elevated serum levels of interleukin-6 and vascular endothelial growth factor (VEGF), capillary pseudothrombus accumulation associated with minimal change nephrotic syndrome , CKD, and WM.
31531336
2019