Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.800 Biomarker disease CTD_human Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. 24816253 2014
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.800 Biomarker disease CTD_human Chronic aspirin use suppresses CDH1 methylation in human gastric mucosa. 19184424 2010
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.800 Biomarker disease CTD_human As the finding of pathogenic CDH1 mutations is useful for management of HDGC families, screening for deletions should be offered to at-risk families. 19168852 2009
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.800 GermlineCausalMutation disease ORPHANET As the finding of pathogenic CDH1 mutations is useful for management of HDGC families, screening for deletions should be offered to at-risk families. 19168852 2009
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.800 Biomarker disease CLINGEN As the finding of pathogenic CDH1 mutations is useful for management of HDGC families, screening for deletions should be offered to at-risk families. 19168852 2009
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.800 GeneticVariation disease UNIPROT However, germline CDH1 mutations have not been described in patients with LBC in non-HDGC families. 17660459 2007
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.800 Biomarker disease CLINGEN Cleft lip/palate and CDH1/E-cadherin mutations in families with hereditary diffuse gastric cancer. 15831593 2006
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.800 Biomarker disease CLINGEN Direct evidence of E-cadherin mutations triggering tumorigenesis has come from the finding of inactivating germline mutations of the gene (CDH1) in hereditary diffuse gastric cancer (HDGC). 12588804 2003
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.800 Biomarker disease CTD_human Direct evidence of E-cadherin mutations triggering tumorigenesis has come from the finding of inactivating germline mutations of the gene (CDH1) in hereditary diffuse gastric cancer (HDGC). 12588804 2003
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.800 Biomarker disease CLINGEN E-cadherin germline missense mutations and cell phenotype: evidence for the independence of cell invasion on the motile capabilities of the cells. 14500541 2003
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.800 GeneticVariation disease UNIPROT E-cadherin gene variants in gastric cancer families whose probands are diagnosed with diffuse gastric cancer. 12216071 2002
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.800 GeneticVariation disease UNIPROT We screened five Korean familial gastric cancer patients to investigate germline mutations of the E-cadherin gene. 10319582 1999
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.800 Biomarker disease CTD_human We have confirmed that germline mutations in the CDH1 gene cause familial gastric cancer in non-Maori populations. 10072428 1999
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.800 Biomarker disease CLINGEN We have confirmed that germline mutations in the CDH1 gene cause familial gastric cancer in non-Maori populations. 10072428 1999
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.800 Biomarker disease CLINGEN A causal role for E-cadherin in the transition from adenoma to carcinoma. 9515965 1998
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.800 Biomarker disease CTD_human E-cadherin germline mutations in familial gastric cancer. 9537325 1998
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.800 Biomarker disease CLINGEN E-cadherin germline mutations in familial gastric cancer. 9537325 1998
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.800 Biomarker disease CLINGEN From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion. 8236461 1993
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.800 Biomarker disease CLINGEN Expression of E- and P-cadherin in gastric carcinomas. 2009537 1991
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.800 Biomarker disease CLINGEN Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. 2070412 1991
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.800 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
0.500 Biomarker disease CTD_human
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
0.500 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.400 Biomarker disease CTD_human Point mutations of K-ras and H-ras genes in forestomach neoplasms from control B6C3F1 mice and following exposure to 1,3-butadiene, isoprene or chloroprene for up to 2-years. 11397402 2001
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.400 Biomarker disease CTD_human DNA adduct measurements, cell proliferation and tumor mutation induction in relation to tumor formation in B6C3F1 mice fed coal tar or benzo[a]pyrene. 10874023 2000