Gene: MUTYH ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 GeneticVariation disease CLINVAR Mutator phenotype of MUTYH-null mouse embryonic stem cells. 12917422 2003
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 Biomarker disease CLINGEN Mutator phenotype of MUTYH-null mouse embryonic stem cells. 12917422 2003
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR Comprehensive analysis of the contribution of germline MYH variation to early-onset colorectal cancer. 14991577 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 GeneticVariation disease CLINVAR Comprehensive analysis of the contribution of germline MYH variation to early-onset colorectal cancer. 14991577 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 GeneticVariation disease CLINVAR Prevalence of the Y165C, G382D and 1395delGGA germline mutations of the MYH gene in Italian patients with adenomatous polyposis coli and colorectal adenomas. 14999774 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR Prevalence of the Y165C, G382D and 1395delGGA germline mutations of the MYH gene in Italian patients with adenomatous polyposis coli and colorectal adenomas. 14999774 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR A novel splice-site variant of the base excision repair gene MYH is associated with production of an aberrant mRNA transcript encoding a truncated MYH protein not localized in the nucleus. 15180946 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 GeneticVariation disease CLINVAR A novel splice-site variant of the base excision repair gene MYH is associated with production of an aberrant mRNA transcript encoding a truncated MYH protein not localized in the nucleus. 15180946 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR High frequency of MYH gene mutations in a subset of patients with familial adenomatous polyposis. 15188161 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 Biomarker disease CLINGEN MUTYH prevents OGG1 or APEX1 from inappropriately processing its substrate or reaction product with its C-terminal domain. 15199168 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR MYH mutations in patients with attenuated and classic polyposis and with young-onset colorectal cancer without polyps. 15236166 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 GeneticVariation disease CLINVAR MYH mutations in patients with attenuated and classic polyposis and with young-onset colorectal cancer without polyps. 15236166 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 GeneticVariation disease CLINVAR Germline MUTYH (MYH) mutations in Portuguese individuals with multiple colorectal adenomas. 15366000 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 GeneticVariation disease UNIPROT Germline MUTYH (MYH) mutations in Portuguese individuals with multiple colorectal adenomas. 15366000 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR Germline MUTYH (MYH) mutations in Portuguese individuals with multiple colorectal adenomas. 15366000 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 Biomarker disease CLINGEN Myh deficiency enhances intestinal tumorigenesis in multiple intestinal neoplasia (ApcMin/+) mice. 15604247 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 GeneticVariation disease CLINVAR The potential for increased clinical sensitivity in genetic testing for polyposis colorectal cancer through the analysis of MYH mutations in North American patients. 15635083 2005
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR The potential for increased clinical sensitivity in genetic testing for polyposis colorectal cancer through the analysis of MYH mutations in North American patients. 15635083 2005
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR Functional characterization of two human MutY homolog (hMYH) missense mutations (R227W and V232F) that lie within the putative hMSH6 binding domain and are associated with hMYH polyposis. 15673720 2005
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 GeneticVariation disease CLINVAR Functional characterization of two human MutY homolog (hMYH) missense mutations (R227W and V232F) that lie within the putative hMSH6 binding domain and are associated with hMYH polyposis. 15673720 2005
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 GeneticVariation disease CLINVAR Mutation analysis of the MYH gene in an Australian series of colorectal polyposis patients with or without germline APC mutations. 15761860 2005
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR Mutation analysis of the MYH gene in an Australian series of colorectal polyposis patients with or without germline APC mutations. 15761860 2005
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR Germline mutations of the MYH gene in Japanese patients with multiple colorectal adenomas. 15890374 2005
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 GeneticVariation disease CLINVAR Germline mutations of the MYH gene in Japanese patients with multiple colorectal adenomas. 15890374 2005
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 GeneticVariation disease CLINVAR Germline susceptibility to colorectal cancer due to base-excision repair gene defects. 15931596 2005