Gene: MUTYH ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR Biallelic MYH germline mutations as cause of Muir-Torre syndrome. 19998059 2010
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR BRAF mutations in multiple sebaceous hyperplasias of patients belonging to MYH-associated polyposis pedigrees. 17273161 2007
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR Cancer risks for monoallelic MUTYH mutation carriers with a family history of colorectal cancer. 21171015 2011
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR Cancer-associated variants and a common polymorphism of MUTYH exhibit reduced repair of oxidative DNA damage using a GFP-based assay in mammalian cells. 22926731 2012
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 GeneticVariation disease CLINVAR Candidate colorectal cancer predisposing gene variants in Chinese early-onset and familial cases. 25892863 2015
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR Cells with pathogenic biallelic mutations in the human MUTYH gene are defective in DNA damage binding and repair. 15987719 2005
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR Characterization of mutant MUTYH proteins associated with familial colorectal cancer. 18534194 2008
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 GeneticVariation disease CLINVAR Characterization of mutant MUTYH proteins associated with familial colorectal cancer. 18534194 2008
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 GeneticVariation disease CLINVAR Clinical evaluation of a multiple-gene sequencing panel for hereditary cancer risk assessment. 24733792 2014
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR Colorectal adenomatous polyposis Associated with MYH mutations: genotype and phenotype characteristics. 17674103 2007
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR Colorectal cancer in a monoallelic MYH mutation carrier. 23625202 2013
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR Colorectal carcinomas in MUTYH-associated polyposis display histopathological similarities to microsatellite unstable carcinomas. 19527492 2009
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR Comprehensive analysis of the contribution of germline MYH variation to early-onset colorectal cancer. 14991577 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 GeneticVariation disease CLINVAR Comprehensive analysis of the contribution of germline MYH variation to early-onset colorectal cancer. 14991577 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 GeneticVariation disease CLINVAR Contribution of APC and MUTYH mutations to familial adenomatous polyposis susceptibility in Hungary. 26446593 2016
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR Contribution of APC and MUTYH mutations to familial adenomatous polyposis susceptibility in Hungary. 26446593 2016
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 GeneticVariation disease CLINVAR Correlation between mutations and mRNA expression of APC and MUTYH genes: new insight into hereditary colorectal polyposis predisposition. 26511139 2015
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR Detection of inherited mutations for hereditary cancer using target enrichment and next generation sequencing. 25151137 2015
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 GeneticVariation disease CLINVAR Detection of inherited mutations for hereditary cancer using target enrichment and next generation sequencing. 25151137 2015
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 GeneticVariation disease CLINVAR Distinct functional consequences of MUTYH variants associated with colorectal cancer: Damaged DNA affinity, glycosylase activity and interaction with PCNA and Hus1. 26377631 2015
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR Distinct functional consequences of MUTYH variants associated with colorectal cancer: Damaged DNA affinity, glycosylase activity and interaction with PCNA and Hus1. 26377631 2015
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR Expanded extracolonic tumor spectrum in MUTYH-associated polyposis. 19732775 2009
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 GeneticVariation disease CLINVAR Expanded extracolonic tumor spectrum in MUTYH-associated polyposis. 19732775 2009
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 CausalMutation disease CLINVAR Factors affecting the treatment of multiple colorectal adenomas. 22773231 2013
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.710 GeneticVariation disease CLINVAR First evidence for digenic inheritance in hereditary colorectal cancer by mutations in the base excision repair genes. 21195604 2011