×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.970
Biomarker
disease
CTD_human
BAG5 Interacts with DJ-1 and Inhibits the Neuroprotective Effects of DJ-1 to Combat Mitochondrial Oxidative Damage.
28348719
2017
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.970
GeneticVariation
disease
UNIPROT
Parkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicity.
23792957
2013
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.970
GeneticVariation
disease
UNIPROT
DJ-1 associates with lipid rafts by palmitoylation and regulates lipid rafts-dependent endocytosis in astrocytes.
23847046
2013
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.970
GeneticVariation
disease
UNIPROT
Human DJ-1 and its homologs are novel glyoxalases.
22523093
2012
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.970
GeneticVariation
disease
UNIPROT
Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation.
19229105
2009
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.970
GeneticVariation
disease
UNIPROT
Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6.
17846173
2007
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.970
GeneticVariation
disease
UNIPROT
Differential effects of Parkinson's disease-associated mutations on stability and folding of DJ-1.
14607841
2004
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.970
GeneticVariation
disease
UNIPROT
Analysis of an early-onset Parkinson's disease cohort for DJ-1 mutations.
15254937
2004
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.970
GeneticVariation
disease
UNIPROT
Analyzing the PARK7 /DJ1 gene in 104 EOPD patients, we identified a third mutation, c.192G>C (p.E64D), associated with EOPD in a patient of Turkish ancestry and characterized the functional significance of this amino acid substitution.
15365989
2004
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.970
GeneticVariation
disease
UNIPROT
The role of pathogenic DJ-1 mutations in Parkinson's disease.
12953260
2003
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.970
Biomarker
disease
GENOMICS_ENGLAND
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism.
12446870
2003
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.970
GeneticVariation
disease
UNIPROT
L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin-proteasome system.
12851414
2003
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.970
GeneticVariation
disease
UNIPROT
A missense mutation (L166P) in DJ-1, linked to familial Parkinson's disease, confers reduced protein stability and impairs homo-oligomerization.
14713311
2003
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.970
GeneticVariation
disease
UNIPROT
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism.
12446870
2003
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.970
Biomarker
disease
GENOMICS_ENGLAND