Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 701
Gene Symbol: BUB1B
BUB1B 		0.640 Biomarker disease BEFREE TALEN-mediated single-base-pair editing identification of an intergenic mutation upstream of BUB1B as causative of PCS (MVA) syndrome. 24344301 2014
Entrez Id: 701
Gene Symbol: BUB1B
BUB1B 		0.640 Biomarker disease BEFREE Here, we report that BUBR1 is essential for the primary cilium formation, and that the PCS (MVA) syndrome is thus a novel ciliopathy. 21389084 2011
Entrez Id: 701
Gene Symbol: BUB1B
BUB1B 		0.640 GeneticVariation disease BEFREE We previously reported that mutations of the BUB1B gene (encoding BubR1) caused premature chromatid separation (PCS) syndrome, a condition characterized by constitutional aneuploidy and a high risk of childhood cancer. 19503101 2009
Entrez Id: 701
Gene Symbol: BUB1B
BUB1B 		0.640 GeneticVariation disease BEFREE We here describe molecular analysis of BUB1B (encoding BubR1) in seven Japanese families with the PCS syndrome. 16411201 2006
Entrez Id: 701
Gene Symbol: BUB1B
BUB1B 		0.640 GeneticVariation disease UNIPROT We here describe molecular analysis of BUB1B (encoding BubR1) in seven Japanese families with the PCS syndrome. 16411201 2006
Entrez Id: 701
Gene Symbol: BUB1B
BUB1B 		0.640 Biomarker disease CTD_human
Entrez Id: 701
Gene Symbol: BUB1B
BUB1B 		0.640 GeneticVariation disease CLINVAR
Entrez Id: 106821730
Gene Symbol: BUB1B-PAK6
BUB1B-PAK6 		0.100 GeneticVariation disease CLINVAR
Entrez Id: 56924
Gene Symbol: PAK6
PAK6 		0.100 GeneticVariation disease CLINVAR
Entrez Id: 5067
Gene Symbol: CNTN3
CNTN3 		0.020 Biomarker disease BEFREE Our proteomic analysis of the EVs derived from HCF and PCS facilitated identification of 1175 proteins, wherein 1026 and 38 proteins were exclusively identified in the EVs derived from HCF (HCF-EVs) and PCS (PCS-EVs), respectively, and 111 proteins were shared in both. 31734339 2019
Entrez Id: 5067
Gene Symbol: CNTN3
CNTN3 		0.020 AlteredExpression disease BEFREE PCS can significantly prolong the duration of the swimming time to exhaustion in mice, decrease BUN, LA levels, increase LDH activities, and the contents of HG in the PCS treated mice. 28419963 2017
Entrez Id: 140821
Gene Symbol: RSS
RSS 		0.010 AlteredExpression disease BEFREE SF36-PCS significantly correlated with the muscular volume; SRS and Oswestry disability index correlated with the erectors spinae volume (p < 0.05). 31811390 2019
Entrez Id: 959
Gene Symbol: CD40LG
CD40LG 		0.010 Biomarker disease BEFREE There was a statistically significant relationship of a positive Western Blot Igenex IGM predicting chronic PCS Pearson χ<sup>2</sup>(1)=6.8866, P=0.009, Fisher's exact score p=0.015 and φ=0.2813 representing a moderate effect size. 31488744 2019
Entrez Id: 3054
Gene Symbol: HCFC1
HCFC1 		0.010 Biomarker disease BEFREE Our proteomic analysis of the EVs derived from HCF and PCS facilitated identification of 1175 proteins, wherein 1026 and 38 proteins were exclusively identified in the EVs derived from HCF (HCF-EVs) and PCS (PCS-EVs), respectively, and 111 proteins were shared in both. 31734339 2019
Entrez Id: 81030
Gene Symbol: ZBP1
ZBP1 		0.010 Biomarker disease BEFREE • mTBI patients with PCS had higher permeability than controls also at NAWM and predilection sites for DAI. 30066251 2019
Entrez Id: 6611
Gene Symbol: SMS
SMS 		0.010 AlteredExpression disease BEFREE SF36-PCS significantly correlated with the muscular volume; SRS and Oswestry disability index correlated with the erectors spinae volume (p < 0.05). 31811390 2019
Entrez Id: 2023
Gene Symbol: ENO1
ENO1 		0.010 Biomarker disease BEFREE Comparing athletes with FPH/PPH to athletes with FPH only, no added PCS risk was noted (χ<sup>2</sup> = 1.64, p = 0.247; OR 2.01, 95% CI 0.68-5.94). 29856298 2018
Entrez Id: 102723356
Gene Symbol: ZFPM2-AS1
ZFPM2-AS1 		0.010 Biomarker disease BEFREE We also compared SCAT3 cognitive and balance performance between adolescents with and without baseline ICD-10 PCS symptoms. 27758158 2017
Entrez Id: 3918
Gene Symbol: LAMC2
LAMC2 		0.010 Biomarker disease BEFREE The CSF:serum albumin ratio was unaltered, suggesting that the BBB is largely intact in PCS. 28283595 2017
Entrez Id: 2729
Gene Symbol: GCLC
GCLC 		0.010 Biomarker disease BEFREE ABBREVIATIONS ED emergency department; GCS Glasgow coma scale; mTBI mild traumatic brain injury; PCS post-concussive symptoms; PTA post-traumatic amnesia; TC trauma control. 28876149 2017
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1 		0.010 Biomarker disease BEFREE Median concentrations of GFAP and YKL-40 were higher in athletes with PCS >1 year compared with controls, although with an overlap between the groups. 28283595 2017
Entrez Id: 1437
Gene Symbol: CSF2
CSF2 		0.010 Biomarker disease BEFREE The CSF:serum albumin ratio was unaltered, suggesting that the BBB is largely intact in PCS. 28283595 2017
Entrez Id: 7357
Gene Symbol: UGCG
UGCG 		0.010 Biomarker disease BEFREE ABBREVIATIONS ED emergency department; GCS Glasgow coma scale; mTBI mild traumatic brain injury; PCS post-concussive symptoms; PTA post-traumatic amnesia; TC trauma control. 28876149 2017
Entrez Id: 2670
Gene Symbol: GFAP
GFAP 		0.010 Biomarker disease BEFREE Median concentrations of GFAP and YKL-40 were higher in athletes with PCS >1 year compared with controls, although with an overlap between the groups. 28283595 2017
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.010 GeneticVariation disease BEFREE HTR1A polymorphisms do not differ in children with PCS. 23992222 2014