Gene: IKZF1 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease GWASDB Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia. 19684604 2009
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease BEFREE The impact of IKZF1 deletion on the prognosis of acute lymphoblastic leukemia: an updated meta-analysis. 25335741 2014
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 Biomarker disease BEFREE Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome. 28190000 2017
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 AlteredExpression disease LHGDN Differential expression of Ikaros isoforms in monozygotic twins with MLL-rearranged precursor-B acute lymphoblastic leukemia. 19131787 2008
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease BEFREE Tumor suppressors BTG1 and IKZF1 cooperate during mouse leukemia development and increase relapse risk in B-cell precursor acute lymphoblastic leukemia patients. 27979924 2017
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease BEFREE Ikaros (IKZF1) alterations and minimal residual disease at day 15 assessed by flow cytometry predict prognosis of childhood BCR/ABL-negative acute lymphoblastic leukemia. 22997141 2013
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 CausalMutation disease CGI
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 Biomarker disease BEFREE Plant homeodomain finger protein 2 as a novel IKAROS target in acute lymphoblastic leukemia. 28994305 2018
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease BEFREE The genomic profile of ETV6-ABL1 acute lymphoblastic leukemia resembled that of BCR-ABL1 and BCR-ABL1-like cases with 80% of patients having concurrent CDKN2A/B and IKZF1 deletions. 27229714 2016
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease BEFREE IKZF1 deletion and co-occurrence with other aberrations in a child with chronic myeloid leukemia progressing to acute lymphoblastic leukemia. 30511400 2019
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease BEFREE Prognostic value of rare IKZF1 deletion in childhood B-cell precursor acute lymphoblastic leukemia: an international collaborative study. 26202931 2016
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 Biomarker disease BEFREE Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. 19129520 2009
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease GWASCAT GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21. 29348612 2018
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease BEFREE IKZF1 rs4132601 polymorphism and acute lymphoblastic leukemia susceptibility: a meta-analysis. 25012940 2015
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease BEFREE Prognostic impact of kinase-activating fusions and IKZF1 deletions in pediatric high-risk B-lineage acute lymphoblastic leukemia. 29507076 2018
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease BEFREE IKZF1 Deletions with COBL Breakpoints Are Not Driven by RAG-Mediated Recombination Events in Acute Lymphoblastic Leukemia. 30877974 2019
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease BEFREE In conclusion, the need of and benefit from introducing IKZF1 deletions as an additional stratification marker for patients with Philadelphia-negative B-cell precursor acute lymphoblastic leukemia remain questionable. 23585525 2013
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GenomicAlterations disease CGI
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease BEFREE IKZF1 deletion is associated with a poor outcome in pediatric B-cell precursor acute lymphoblastic leukemia in Japan. 23930217 2013
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 AlteredExpression disease BEFREE IKZF1 alterations and expression of CRLF2 predict prognosis in adult Chinese patients with B-cell precursor acute lymphoblastic leukemia. 27157479 2017
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease BEFREE IKZF1 deletions predict a poor prognosis in children with B-cell progenitor acute lymphoblastic leukemia: a multicenter analysis in Taiwan. 21740479 2011
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease BEFREE IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: a GIMEMA AL WP report. 19770381 2009
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease BEFREE An intragenic ERG deletion is a marker of an oncogenic subtype of B-cell precursor acute lymphoblastic leukemia with a favorable outcome despite frequent IKZF1 deletions. 24064621 2014
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 Biomarker disease BEFREE IKZF1 and PAX5 deletions were observed in 13 and 17% of B-LBL, respectively, which was similar to the reported frequency in B-ALL. 27957801 2017
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease BEFREE Breakpoint-specific multiplex polymerase chain reaction allows the detection of IKZF1 intragenic deletions and minimal residual disease monitoring in B-cell precursor acute lymphoblastic leukemia. 23065506 2013