Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 GeneticVariation disease BEFREE The impact of IKZF1 deletion on the prognosis of acute lymphoblastic leukemia: an updated meta-analysis. 25335741 2014
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 Biomarker disease BEFREE Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome. 28190000 2017
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 GeneticVariation disease BEFREE Tumor suppressors BTG1 and IKZF1 cooperate during mouse leukemia development and increase relapse risk in B-cell precursor acute lymphoblastic leukemia patients. 27979924 2017
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 GeneticVariation disease BEFREE Ikaros (IKZF1) alterations and minimal residual disease at day 15 assessed by flow cytometry predict prognosis of childhood BCR/ABL-negative acute lymphoblastic leukemia. 22997141 2013
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 Biomarker disease BEFREE Plant homeodomain finger protein 2 as a novel IKAROS target in acute lymphoblastic leukemia. 28994305 2018
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 GeneticVariation disease BEFREE The genomic profile of ETV6-ABL1 acute lymphoblastic leukemia resembled that of BCR-ABL1 and BCR-ABL1-like cases with 80% of patients having concurrent CDKN2A/B and IKZF1 deletions. 27229714 2016
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 GeneticVariation disease BEFREE IKZF1 deletion and co-occurrence with other aberrations in a child with chronic myeloid leukemia progressing to acute lymphoblastic leukemia. 30511400 2019
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 GeneticVariation disease BEFREE Prognostic value of rare IKZF1 deletion in childhood B-cell precursor acute lymphoblastic leukemia: an international collaborative study. 26202931 2016
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 Biomarker disease BEFREE Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. 19129520 2009
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 GeneticVariation disease BEFREE IKZF1 rs4132601 polymorphism and acute lymphoblastic leukemia susceptibility: a meta-analysis. 25012940 2015
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 GeneticVariation disease BEFREE Prognostic impact of kinase-activating fusions and IKZF1 deletions in pediatric high-risk B-lineage acute lymphoblastic leukemia. 29507076 2018
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 GeneticVariation disease BEFREE IKZF1 Deletions with COBL Breakpoints Are Not Driven by RAG-Mediated Recombination Events in Acute Lymphoblastic Leukemia. 30877974 2019
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 GeneticVariation disease BEFREE In conclusion, the need of and benefit from introducing IKZF1 deletions as an additional stratification marker for patients with Philadelphia-negative B-cell precursor acute lymphoblastic leukemia remain questionable. 23585525 2013
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 GeneticVariation disease BEFREE IKZF1 deletion is associated with a poor outcome in pediatric B-cell precursor acute lymphoblastic leukemia in Japan. 23930217 2013
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 AlteredExpression disease BEFREE IKZF1 alterations and expression of CRLF2 predict prognosis in adult Chinese patients with B-cell precursor acute lymphoblastic leukemia. 27157479 2017
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 GeneticVariation disease BEFREE IKZF1 deletions predict a poor prognosis in children with B-cell progenitor acute lymphoblastic leukemia: a multicenter analysis in Taiwan. 21740479 2011
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 GeneticVariation disease BEFREE IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: a GIMEMA AL WP report. 19770381 2009
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 GeneticVariation disease BEFREE An intragenic ERG deletion is a marker of an oncogenic subtype of B-cell precursor acute lymphoblastic leukemia with a favorable outcome despite frequent IKZF1 deletions. 24064621 2014
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 Biomarker disease BEFREE IKZF1 and PAX5 deletions were observed in 13 and 17% of B-LBL, respectively, which was similar to the reported frequency in B-ALL. 27957801 2017
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 GeneticVariation disease BEFREE Breakpoint-specific multiplex polymerase chain reaction allows the detection of IKZF1 intragenic deletions and minimal residual disease monitoring in B-cell precursor acute lymphoblastic leukemia. 23065506 2013
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 GeneticVariation disease BEFREE IKZF1 deletion (ΔIKZF1) is an important predictor of relapse in childhood B-cell precursor acute lymphoblastic leukemia. 27419633 2016
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 GeneticVariation disease BEFREE Acute lymphoblastic leukemia in a patient with Greig cephalopolysyndactyly and interstitial deletion of chromosome 7 del(7)(p11.2 p14) involving the GLI3 and ZNFN1A1 genes. 15390181 2005
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 Biomarker disease BEFREE By contrast, the MRD15 was higher in Ikaros family Zinc Finger Protein 1 (<i>IKZF1)</i>-deleted BCP-ALL patients than in BCP-ALL patients without <i>IKZF1</i> deletions [1.18% (0.06-12.0%) vs 0.33% (0.03-2.6%); p=0.003]. 29899835 2018
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 GeneticVariation disease BEFREE IKZF1 Gene Deletion in Pediatric Patients Diagnosed with Acute Lymphoblastic Leukemia in Mexico. 30974435 2019
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
0.700 Biomarker disease BEFREE The many faces of IKZF1 in B-cell precursor acute lymphoblastic leukemia. 29519871 2018