×
Entrez Id:
2322
Gene Symbol:
FLT3
FLT3
0.800
Biomarker
disease
CTD_human
×
Entrez Id:
2322
Gene Symbol:
FLT3
FLT3
0.800
GeneticVariation
disease
UNIPROT
×
Entrez Id:
2322
Gene Symbol:
FLT3
FLT3
0.800
CausalMutation
disease
CGI
×
Entrez Id:
5079
Gene Symbol:
PAX5
PAX5
0.700
Biomarker
disease
CTD_human
Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options.
26214592
2015
×
Entrez Id:
5079
Gene Symbol:
PAX5
PAX5
0.700
GeneticVariation
disease
UNIPROT
A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia.
24013638
2013
×
Entrez Id:
10320
Gene Symbol:
IKZF1
IKZF1
0.700
Biomarker
disease
CTD_human
Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia.
19684604
2009
×
Entrez Id:
10320
Gene Symbol:
IKZF1
IKZF1
0.700
CausalMutation
disease
CGI
×
Entrez Id:
10320
Gene Symbol:
IKZF1
IKZF1
0.700
GenomicAlterations
disease
CGI
×
Entrez Id:
5079
Gene Symbol:
PAX5
PAX5
0.700
CausalMutation
disease
CGI
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.630
Biomarker
disease
GENOMICS_ENGLAND
Four children with acute lymphoblastic leukemia have been reported to be heterozygous for a germline and/or somatic missense mutation in NBS1 , leading to the I171V substitution.
15338273
2004
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.630
Biomarker
disease
GENOMICS_ENGLAND
Mutations in the Nijmegen Breakage Syndrome gene (NBS1) in childhood acute lymphoblastic leukemia (ALL).
11325820
2001
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.630
Biomarker
disease
CTD_human
×
Entrez Id:
25
Gene Symbol:
ABL1
ABL1
0.600
Biomarker
disease
CTD_human
Antileukaemia effect of rapamycin alone or in combination with daunorubicin on Ph+ acute lymphoblastic leukaemia cell line.
21898527
2012
×
Entrez Id:
64109
Gene Symbol:
CRLF2
CRLF2
0.600
Biomarker
disease
CTD_human
Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia .
19838194
2009
×
Entrez Id:
25
Gene Symbol:
ABL1
ABL1
0.600
Biomarker
disease
CTD_human
In vitro drug resistance profile of Philadelphia positive acute lymphoblastic leukemia is heterogeneous and related to age: a report of the Dutch and German Leukemia Study Groups.
11984797
2002
×
Entrez Id:
25
Gene Symbol:
ABL1
ABL1
0.600
CausalMutation
disease
CGI
×
Entrez Id:
64109
Gene Symbol:
CRLF2
CRLF2
0.600
CausalMutation
disease
CGI
×
Entrez Id:
10019
Gene Symbol:
SH2B3
SH2B3
0.530
Biomarker
disease
GENOMICS_ENGLAND
Genetic loss of SH2B3 in acute lymphoblastic leukemia .
23908464
2013
×
Entrez Id:
10019
Gene Symbol:
SH2B3
SH2B3
0.530
CausalMutation
disease
CGI
×
Entrez Id:
613
Gene Symbol:
BCR
BCR
0.500
Biomarker
disease
CTD_human
×
Entrez Id:
84159
Gene Symbol:
ARID5B
ARID5B
0.480
Biomarker
disease
CTD_human
Germline genomic variants associated with childhood acute lymphoblastic leukemia.
19684603
2009
×
Entrez Id:
84159
Gene Symbol:
ARID5B
ARID5B
0.480
Biomarker
disease
CTD_human
Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia.
19684604
2009
×
Entrez Id:
6886
Gene Symbol:
TAL1
TAL1
0.460
Biomarker
disease
CTD_human
×
Entrez Id:
8021
Gene Symbol:
NUP214
NUP214
0.420
Biomarker
disease
CTD_human
×
Entrez Id:
3981
Gene Symbol:
LIG4
LIG4
0.410
Biomarker
disease
GENOMICS_ENGLAND
Germline Genetic Predisposition to Hematologic Malignancy.
28297620
2017