Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 26681
Gene Symbol: OR4G1P
OR4G1P
0.010 Biomarker disease BEFREE <b>Approach:</b> To test the hypothesis that treatment with OLB together with exercise vs. exercise alone would induce feedback action of GH, pancreatic polypeptide (PP), peptide tyrosine tyrosine (PYY), and leptin on ghrelin in Czech women with BN and in healthy-weight Czech women (HW). 30915029 2019
Entrez Id: 2688
Gene Symbol: GH1
GH1
0.010 Biomarker disease BEFREE <b>Approach:</b> To test the hypothesis that treatment with OLB together with exercise vs. exercise alone would induce feedback action of GH, pancreatic polypeptide (PP), peptide tyrosine tyrosine (PYY), and leptin on ghrelin in Czech women with BN and in healthy-weight Czech women (HW). 30915029 2019
Entrez Id: 5697
Gene Symbol: PYY
PYY
0.030 Biomarker disease BEFREE <b>Approach:</b> To test the hypothesis that treatment with OLB together with exercise vs. exercise alone would induce feedback action of GH, pancreatic polypeptide (PP), peptide tyrosine tyrosine (PYY), and leptin on ghrelin in Czech women with BN and in healthy-weight Czech women (HW). 30915029 2019
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.070 Biomarker disease BEFREE <b>Approach:</b> To test the hypothesis that treatment with OLB together with exercise vs. exercise alone would induce feedback action of GH, pancreatic polypeptide (PP), peptide tyrosine tyrosine (PYY), and leptin on ghrelin in Czech women with BN and in healthy-weight Czech women (HW). 30915029 2019
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
0.050 GeneticVariation disease BEFREE 5-HT2A receptor gene polymorphisms in anorexia nervosa and bulimia nervosa. 10624828 1999
Entrez Id: 1312
Gene Symbol: COMT
COMT
0.060 GeneticVariation disease BEFREE COMT Val158 allele was overrepresented and the medium-activity haplotype was underrepresented in BN with childhood ADHD history (p=0.010). 21300128 2011
Entrez Id: 79068
Gene Symbol: FTO
FTO
0.010 GeneticVariation disease BEFREE Fat mass and obesity-associated gene (FTO) in eating disorders: evidence for association of the rs9939609 obesity risk allele with bulimia nervosa and anorexia nervosa. 22797368 2012
Entrez Id: 181
Gene Symbol: AGRP
AGRP
0.010 GeneticVariation disease BEFREE AGRP rs13338499 polymorphism was associated with lowest illness-related BMI in those with AN (p = 0.0013), and NTRK2 rs1042571 was associated with highest BMI in those with BN (p = 0.0018). 24831852 2014
Entrez Id: 4170
Gene Symbol: MCL1
MCL1
0.030 Biomarker disease BEFREE EAT-26 test was used to screen classic eating disorders (anorexia and bulimia). 30080233 2018
Entrez Id: 1815
Gene Symbol: DRD4
DRD4
0.050 Biomarker disease BEFREE A DRD4/BDNF gene-gene interaction associated with maximum BMI in women with bulimia nervosa. 17922530 2008
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.090 GeneticVariation disease BEFREE A DRD4/BDNF gene-gene interaction associated with maximum BMI in women with bulimia nervosa. 17922530 2008
Entrez Id: 3481
Gene Symbol: IGF2
IGF2
0.010 GeneticVariation disease BEFREE A highly significant association was observed between the IGF2 ApaI G allele and scores on the Eating Attitudes Test overall and each of its subscales (bulimia, dieting, and oral control). 16330588 2005
Entrez Id: 1815
Gene Symbol: DRD4
DRD4
0.050 Biomarker disease BEFREE A season-of-birth/DRD4 interaction predicts maximal body mass index in women with bulimia nervosa. 20336060 2010
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.100 AlteredExpression disease BEFREE A short (s) allele in the promoter region of the 5-hydroxytryptamine (5-HT) transporter gene (5HTTLPR) has been associated with low transcription of the 5-HT transporter protein, and with clinical manifestations including impulsivity, affective disorder, and bulimia nervosa. 15690467 2005
Entrez Id: 4160
Gene Symbol: MC4R
MC4R
0.030 GeneticVariation disease BEFREE A single patient with both extreme obesity and BN had a haplo-insufficiency mutation in the MC4R. 12140789 2002
Entrez Id: 611
Gene Symbol: OPN1SW
OPN1SW
0.070 Biomarker disease BEFREE Adolescents (N = 110) were randomly assigned to FBT-BN or CBT-A and completed assessments of eating pathology and OC-ED behaviour. 30734406 2019
Entrez Id: 3855
Gene Symbol: KRT7
KRT7
0.040 GeneticVariation disease BEFREE Adult inpatients (<i>n</i> = 166) with longstanding DSM-IV Anorexia Nervosa, Bulimia Nervosa (BN) or Eating Disorder not Otherwise Specified (EDNOS) completed the CET instrument, Eating Disorder examination questionnaire (EDE-Q), Beck Depression Inventory-II (BDI-II) and Symptom checklist-90 (SCL-90). 31695652 2019
Entrez Id: 51540
Gene Symbol: SCLY
SCLY
0.040 GeneticVariation disease BEFREE Adult inpatients (<i>n</i> = 166) with longstanding DSM-IV Anorexia Nervosa, Bulimia Nervosa (BN) or Eating Disorder not Otherwise Specified (EDNOS) completed the CET instrument, Eating Disorder examination questionnaire (EDE-Q), Beck Depression Inventory-II (BDI-II) and Symptom checklist-90 (SCL-90). 31695652 2019
Entrez Id: 6886
Gene Symbol: TAL1
TAL1
0.040 GeneticVariation disease BEFREE Adult inpatients (<i>n</i> = 166) with longstanding DSM-IV Anorexia Nervosa, Bulimia Nervosa (BN) or Eating Disorder not Otherwise Specified (EDNOS) completed the CET instrument, Eating Disorder examination questionnaire (EDE-Q), Beck Depression Inventory-II (BDI-II) and Symptom checklist-90 (SCL-90). 31695652 2019
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2
0.010 GeneticVariation disease BEFREE AGRP rs13338499 polymorphism was associated with lowest illness-related BMI in those with AN (p = 0.0013), and NTRK2 rs1042571 was associated with highest BMI in those with BN (p = 0.0018). 24831852 2014
Entrez Id: 3358
Gene Symbol: HTR2C
HTR2C
0.030 Biomarker disease BEFREE Allelic variation of the 5-HT2C receptor (HTR2C) in bulimia nervosa and binge eating disorder. 10412190 1999
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
0.050 GeneticVariation disease BEFREE Analysis of the -1438 G/A polymorphism of the 5-HT2A serotonin receptor gene in bulimia nervosa patients with or without a history of anorexia nervosa. 15167698 2004
Entrez Id: 2875
Gene Symbol: GPT
GPT
0.010 Biomarker disease BEFREE Anorexia and bulimia nervosa are associated with poor periodontal condition, elevated salivary concentrations of total protein, AST, ALT, and LDH, decreased salivary flow rate and a significant adverse impact on OHRQoL. 31361025 2019
Entrez Id: 51738
Gene Symbol: GHRL
GHRL
0.040 Biomarker disease LHGDN Appetite-related gut peptides, ghrelin, PYY, and GLP-1 in obese women with and without binge eating disorder (BED). 18534636 2008
Entrez Id: 10810
Gene Symbol: WASF3
WASF3
0.010 Biomarker disease BEFREE As only one twin pair was concordant for lifetime bulimia nervosa at Wave 3 assessment, ordinal measures of all assessments were used in a multivariate genetic analysis. 10473319 1999