Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1
0.010 Biomarker disease BEFREE The aim of the current study is to explore how therapists running a guided physical exercise and dietary therapy programme (PED-t) experience their contribution to the treatment of patients with bulimia nervosa and binge eating disorder. 29330176 2018
Entrez Id: 6462
Gene Symbol: SHBG
SHBG
0.010 GeneticVariation disease BEFREE Forty-six women with bulimia nervosa (BN), 31 with eating disorder not otherwise specified, purging type (EDNOS P) and 56 matched healthy controls were studied with respect to serum testosterone (T), 5alpha-dihydrotestosterone (DHT), sex hormone-binding globulin (SHBG), deyhydroepiahndrosterone sulfate (DHEAS) and luteinizing hormone (LH) and to ovarian morphology. 30172682 2019
Entrez Id: 51540
Gene Symbol: SCLY
SCLY
0.040 Biomarker disease BEFREE There were significant differences in the global indices of the SCL-90R inventory between the three ED groups (Anorexia Nervosa (AN), Bulimia Nervosa (BN) and binge-eating disorder; ANOVA-p < 0.05). 29879886 2018
Entrez Id: 51540
Gene Symbol: SCLY
SCLY
0.040 GeneticVariation disease BEFREE Adult inpatients (<i>n</i> = 166) with longstanding DSM-IV Anorexia Nervosa, Bulimia Nervosa (BN) or Eating Disorder not Otherwise Specified (EDNOS) completed the CET instrument, Eating Disorder examination questionnaire (EDE-Q), Beck Depression Inventory-II (BDI-II) and Symptom checklist-90 (SCL-90). 31695652 2019
Entrez Id: 51540
Gene Symbol: SCLY
SCLY
0.040 GeneticVariation disease BEFREE Haplotype <i>*6</i> in <i>KCTD15</i> was more frequent in controls (OR = 0.40 [0.20-0.80], <i>p</i> = .009 for anorexia nervosa), while haplotype <i>*4</i> in <i>TFAP2B</i> affected all three scales of the SCL-90R inventory in BN patients (<i>p</i> ≤ .01). 28948079 2017
Entrez Id: 51540
Gene Symbol: SCLY
SCLY
0.040 GeneticVariation disease BEFREE Two-hundred-and-seventy-three ED patients [199 with Anorexia Nervosa (AN) and 74 with Bulimia Nervosa (BN)] completed the SCL-90R inventory and were genotyped for four functional, clinically relevant DRD4 polymorphisms: three variants in the promoter region [120-bp tandem repeat (TR, long vs. short allele), C-616G and C-521 T] and a variable number of tandem repeats (VNTR) in exon 3 (7R vs. non-7R allele). 29455021 2018
Entrez Id: 5697
Gene Symbol: PYY
PYY
0.030 Biomarker disease BEFREE This study comes from a series of nested studies examining ingestive behaviors in bulimic syndromes and specifically evaluated the satiety peptide YY (PYY) and the hunger peptide ghrelin in women with PD (n = 25), bulimia nervosa-purging (BNp) (n = 26), and controls (n = 26). 29219202 2018
Entrez Id: 5697
Gene Symbol: PYY
PYY
0.030 Biomarker disease BEFREE In studies of biological correlates, women with purging disorder demonstrated significantly greater postprandial increases in the satiety peptide, peptide tyrosine tyrosine, compared to women with bulimia nervosa and controls, and these differences predicted greater gastrointestinal distress in purging disorder. 31306252 2019
Entrez Id: 5697
Gene Symbol: PYY
PYY
0.030 Biomarker disease BEFREE <b>Approach:</b> To test the hypothesis that treatment with OLB together with exercise vs. exercise alone would induce feedback action of GH, pancreatic polypeptide (PP), peptide tyrosine tyrosine (PYY), and leptin on ghrelin in Czech women with BN and in healthy-weight Czech women (HW). 30915029 2019
Entrez Id: 8682
Gene Symbol: PEA15
PEA15
0.010 Biomarker disease BEFREE The aim of the current study is to explore how therapists running a guided physical exercise and dietary therapy programme (PED-t) experience their contribution to the treatment of patients with bulimia nervosa and binge eating disorder. 29330176 2018
Entrez Id: 5021
Gene Symbol: OXTR
OXTR
0.010 GeneticVariation disease BEFREE We found a positive association between the G allele of OXTR rs53576 and BN. 25773927 2015
Entrez Id: 26681
Gene Symbol: OR4G1P
OR4G1P
0.010 Biomarker disease BEFREE <b>Approach:</b> To test the hypothesis that treatment with OLB together with exercise vs. exercise alone would induce feedback action of GH, pancreatic polypeptide (PP), peptide tyrosine tyrosine (PYY), and leptin on ghrelin in Czech women with BN and in healthy-weight Czech women (HW). 30915029 2019
Entrez Id: 144125
Gene Symbol: OR2AG1
OR2AG1
0.010 GeneticVariation disease BEFREE Studies showing serotonin receptor type 3 (5-HT3) receptors to mediate food intake depression (anorexic response) have triggered our interest in investigating the putative role of variants in the 5-HT3 receptor genes, HTR3A and HTR3B, in the susceptibility to anorexia nervosa (AN) and bulimia nervosa (BN). 19741568 2009
Entrez Id: 611
Gene Symbol: OPN1SW
OPN1SW
0.070 Biomarker disease BEFREE This suggests that bulimia nervosa may be effectively treated with CBT-T in the context of gender dysphoria. 30843609 2019
Entrez Id: 611
Gene Symbol: OPN1SW
OPN1SW
0.070 Biomarker disease BEFREE Adolescents (N = 110) were randomly assigned to FBT-BN or CBT-A and completed assessments of eating pathology and OC-ED behaviour. 30734406 2019
Entrez Id: 611
Gene Symbol: OPN1SW
OPN1SW
0.070 Biomarker disease BEFREE The aim of this study was to provide an update of the most recent (since January 2014) enhanced cognitive behavioural therapy (CBT-E) effectiveness studies (randomized controlled trials and open trials) on bulimia nervosa, binge eating disorder and transdiagnostic samples. 30188385 2018
Entrez Id: 611
Gene Symbol: OPN1SW
OPN1SW
0.070 Biomarker disease BEFREE Mood intolerance, a maintenance factor of BN but external to eating disorder pathological features (typically addressed within CBT), emerged as the primary clinical variable distinguishing the severity groups showing a differential treatment response. 27435722 2017
Entrez Id: 611
Gene Symbol: OPN1SW
OPN1SW
0.070 Biomarker disease BEFREE Moreover, findings demonstrate that, in addition to being the front-running treatment for BN symptoms, CBT might also be the most effective psychotherapy for improving the symptoms of depression that commonly co-occur in BN. 28804915 2017
Entrez Id: 611
Gene Symbol: OPN1SW
OPN1SW
0.070 GeneticVariation disease BEFREE Sixty-six men and women with DSM-5 binge-eating disorder (BED) or bulimia nervosa (BN) were randomized to receive eight sessions of CBT-GSH + Noom (n = 33) or CBT-GSH (n = 33) over 12 weeks. 28960384 2017
Entrez Id: 611
Gene Symbol: OPN1SW
OPN1SW
0.070 Biomarker disease BEFREE The purpose of this investigation was to examine the indirect effects of Integrative Cognitive-Affective Therapy (ICAT-BN) and Cognitive-Behavioral Therapy-Enhanced (CBT-E) on bulimia nervosa (BN) treatment outcome through three hypothesized maintenance variables: emotion regulation, self-directed behavior, and self-discrepancy. 28117906 2017
Entrez Id: 4948
Gene Symbol: OCA2
OCA2
0.010 Biomarker disease BEFREE The aim of the current study is to explore how therapists running a guided physical exercise and dietary therapy programme (PED-t) experience their contribution to the treatment of patients with bulimia nervosa and binge eating disorder. 29330176 2018
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2
0.010 GeneticVariation disease BEFREE AGRP rs13338499 polymorphism was associated with lowest illness-related BMI in those with AN (p = 0.0013), and NTRK2 rs1042571 was associated with highest BMI in those with BN (p = 0.0018). 24831852 2014
Entrez Id: 93034
Gene Symbol: NT5C1B
NT5C1B
0.010 Biomarker disease BEFREE The current results implicate the following genes: CLEC5A, LOC136242, TSHZ1, and SYTL5 for the AN spectrum phenotype; NT5C1B for the BN spectrum phenotype; and ATP8A2 for the disordered eating behaviors phenotype. 23568457 2013
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
0.030 GeneticVariation disease BEFREE Interaction of the BcII glucocorticoid receptor polymorphism and childhood abuse in Bulimia Nervosa (BN): relationship to BN and to associated trait manifestations. 22088926 2012
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
0.030 PosttranslationalModification disease BEFREE Our findings associate BN (when accompanied by BPD or suicidality) with hypermethylation of certain GR exon 1C promoter sites. 23417893 2013