×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
Biomarker
disease
GENOMICS_ENGLAND
Evaluating the Clinical Validity of Hypertrophic Cardiomyopathy Genes.
30681346
2019
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
GeneticVariation
disease
CLINVAR
Reassessment of Mendelian gene pathogenicity using 7,855 cardiomyopathy cases and 60,706 reference samples.
27532257
2017
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
GeneticVariation
disease
CLINVAR
Nonfamilial Hypertrophic Cardiomyopathy: Prevalence, Natural History, and Clinical Implications.
28408708
2017
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
CausalMutation
disease
CLINVAR
Reassessment of Mendelian gene pathogenicity using 7,855 cardiomyopathy cases and 60,706 reference samples.
27532257
2017
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
CausalMutation
disease
CLINVAR
Mutations in troponin T associated with Hypertrophic Cardiomyopathy increase Ca(2+)-sensitivity and suppress the modulation of Ca(2+)-sensitivity by troponin I phosphorylation.
27036851
2016
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
GeneticVariation
disease
CLINVAR
Evaluation of the Mayo Clinic Phenotype-Based Genotype Predictor Score in Patients with Clinically Diagnosed Hypertrophic Cardiomyopathy.
26914223
2016
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
CausalMutation
disease
CLINVAR
Clinical and Prognostic Profiles of Cardiomyopathies Caused by Mutations in the Troponin T Gene.
26507537
2016
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
CausalMutation
disease
CLINVAR
Establishing disease causality for a novel gene variant in familial dilated cardiomyopathy using a functional in-vitro assay of regulated thin filaments and human cardiac myosin.
26498512
2015
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
CausalMutation
disease
CLINVAR
Exome Sequencing Identifies Pathogenic and Modifier Mutations in a Child With Sporadic Dilated Cardiomyopathy.
26656454
2015
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
CausalMutation
disease
CLINVAR
A low prevalence of sarcomeric gene variants in a Chinese cohort with left ventricular non-compaction.
24691700
2015
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
CausalMutation
disease
CLINVAR
Clinical phenotype and outcome of hypertrophic cardiomyopathy associated with thin-filament gene mutations.
25524337
2014
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
CausalMutation
disease
CLINVAR
A novel arginine to tryptophan (R144W) mutation in troponin T (cTnT) gene in an indian multigenerational family with dilated cardiomyopathy (FDCM).
24992688
2014
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
CausalMutation
disease
CLINVAR
Characterization of a phenotype-based genetic test prediction score for unrelated patients with hypertrophic cardiomyopathy.
24793961
2014
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
CausalMutation
disease
CLINVAR
Allosteric effects of cardiac troponin TNT1 mutations on actomyosin binding: a novel pathogenic mechanism for hypertrophic cardiomyopathy.
24480310
2014
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
GeneticVariation
disease
CLINVAR
Sarcomere mutation-specific expression patterns in human hypertrophic cardiomyopathy.
25031304
2014
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
CausalMutation
disease
CLINVAR
Hypertrophic cardiomyopathy: one gene … but many phenotypes.
24792744
2014
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
CausalMutation
disease
CLINVAR
Analysis of the molecular pathogenesis of cardiomyopathy-causing cTnT mutants I79N, ΔE96, and ΔK210.
23663841
2013
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
CausalMutation
disease
CLINVAR
Early results of sarcomeric gene screening from the Egyptian National BA-HCM Program.
23233322
2013
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
GeneticVariation
disease
CLINVAR
Genetic complexity in hypertrophic cardiomyopathy revealed by high-throughput sequencing.
23396983
2013
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
CausalMutation
disease
CLINVAR
Poor prognosis of rare sarcomeric gene variants in patients with dilated cardiomyopathy.
24119082
2013
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
CausalMutation
disease
CLINVAR
Familial dilated cardiomyopathy mutations uncouple troponin I phosphorylation from changes in myofibrillar Ca²⁺ sensitivity.
23539503
2013
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
CausalMutation
disease
CLINVAR
Usefulness of running wheel for detection of congestive heart failure in dilated cardiomyopathy mouse model.
23383212
2013
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
CausalMutation
disease
CLINVAR
Genetic complexity in hypertrophic cardiomyopathy revealed by high-throughput sequencing.
23396983
2013
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
GeneticVariation
disease
CLINVAR
Genetic analysis in 418 index patients with idiopathic dilated cardiomyopathy: overview of 10 years' experience.
23349452
2013
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.600
CausalMutation
disease
CLINVAR
A systematic approach to assessing the clinical significance of genetic variants.
24033266
2013