Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 80339
Gene Symbol: PNPLA3
PNPLA3 		0.500 GeneticVariation disease UNIPROT Screening for rare variants in the PNPLA3 gene in obese liver biopsy patients. 27288299 2016
Entrez Id: 80339
Gene Symbol: PNPLA3
PNPLA3 		0.500 Biomarker disease MGD Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis. 24917523 2015
Entrez Id: 80339
Gene Symbol: PNPLA3
PNPLA3 		0.500 GeneticVariation disease UNIPROT A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans. 19224197 2009
Entrez Id: 80339
Gene Symbol: PNPLA3
PNPLA3 		0.500 GeneticVariation disease UNIPROT A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity. 19738004 2009
Entrez Id: 80339
Gene Symbol: PNPLA3
PNPLA3 		0.500 GeneticVariation disease UNIPROT Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease. 18820647 2008
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4 		0.200 Therapeutic disease RGD Curative effect of arjunolic acid from Terminalia arjuna in non-alcoholic fatty liver disease models. 30257410 2018
Entrez Id: 4023
Gene Symbol: LPL
LPL 		0.200 Therapeutic disease RGD Thiazolidinedione induces a therapeutic effect on hepatosteatosis by regulating stearoyl-CoA desaturase-1, lipase activity, leptin and resistin. 30214514 2018
Entrez Id: 2308
Gene Symbol: FOXO1
FOXO1 		0.200 Therapeutic disease RGD Enhancement of Adiponectin Ameliorates Nonalcoholic Fatty Liver Disease via Inhibition of FoxO1 in Type I Diabetic Rats. 30186875 2018
Entrez Id: 57817
Gene Symbol: HAMP
HAMP 		0.200 Biomarker disease RGD Hepcidin levels correlate to liver iron content, but not steatohepatitis, in non-alcoholic fatty liver disease. 29871592 2018
Entrez Id: 10857
Gene Symbol: PGRMC1
PGRMC1 		0.200 Biomarker disease MGD Loss of progesterone receptor membrane component 1 promotes hepatic steatosis via the induced de novo lipogenesis. 30356113 2018
Entrez Id: 5264
Gene Symbol: PHYH
PHYH 		0.200 Therapeutic disease RGD Isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomics for the investigation of the effect of Hugan Qingzhi on non-alcoholic fatty liver disease in rats. 29031784 2018
Entrez Id: 3643
Gene Symbol: INSR
INSR 		0.200 SusceptibilityMutation disease RGD Insulin resistance promotes Lysyl Oxidase Like 2 induction and fibrosis accumulation in non-alcoholic fatty liver disease. 28468951 2017
Entrez Id: 1728
Gene Symbol: NQO1
NQO1 		0.200 Therapeutic disease RGD Yinchen Linggui Zhugan Decoction Ameliorates Nonalcoholic Fatty Liver Disease in Rats by Regulating the Nrf2/ARE Signaling Pathway. 28932253 2017
Entrez Id: 6352
Gene Symbol: CCL5
CCL5 		0.200 Therapeutic disease RGD Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress. 27639593 2017
Entrez Id: 6352
Gene Symbol: CCL5
CCL5 		0.200 ModifyingMutation disease RGD Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress. 27639593 2017
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		0.200 Biomarker disease MGD NLRP3 mutation and cochlear autoinflammation cause syndromic and nonsyndromic hearing loss DFNA34 responsive to anakinra therapy. 28847925 2017
Entrez Id: 57817
Gene Symbol: HAMP
HAMP 		0.200 Biomarker disease RGD  Differences in hepatic expression of iron, inflammation and stress-related genes in patients with nonalcoholic steatohepatitis. 28051796 2017
Entrez Id: 3643
Gene Symbol: INSR
INSR 		0.200 Therapeutic disease RGD [Effects of Lactobacillus paracasei N1115 combined with fructooligosaccharides on non-alcoholic fatty liver disease induced by high-fat diet in mice]. 29325294 2017
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		0.200 Biomarker disease MGD Lack of NLRP3-inflammasome leads to gut-liver axis derangement, gut dysbiosis and a worsened phenotype in a mouse model of NAFLD. 28939830 2017
Entrez Id: 51092
Gene Symbol: SIDT2
SIDT2 		0.200 Biomarker disease MGD Spontaneous nonalcoholic fatty liver disease and ER stress in Sidt2 deficiency mice. 27233614 2016
Entrez Id: 4023
Gene Symbol: LPL
LPL 		0.200 Therapeutic disease RGD [Preventive and therapeutic effects of compound ginkgo extract in rats with nonalcoholic steatohepatitis induced by high-fat, high-fructose diet]. 27978932 2016
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		0.200 Biomarker disease RGD Kupffer cell depletion protects against the steatosis, but not the liver damage, induced by marginal-copper, high-fructose diet in male rats. 25813056 2015
Entrez Id: 3416
Gene Symbol: IDE
IDE 		0.200 Biomarker disease RGD Berberine Reduces Neurotoxicity Related to Nonalcoholic Steatohepatitis in Rats. 26576191 2015
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.200 Biomarker disease MGD Oxidative stress promotes pathologic polyploidization in nonalcoholic fatty liver disease. 25621497 2015
Entrez Id: 9927
Gene Symbol: MFN2
MFN2 		0.200 Therapeutic disease RGD Effects of salvianolic acid B on liver mitochondria of rats with nonalcoholic steatohepatitis. 26401075 2015