| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.100 | AlteredExpression | disease | BEFREE | The level of miR-371-5p was associated with clinical stage and distant metastasis in patients with NPC, and was inversely associated with the protein level of BCL-2 in NPC tissues. | 29844823 | 2018 | ||||
|
0.100 | Biomarker | disease | BEFREE | In this study, the authors investigated EBV-encoded RNA-1 (EBER1) transcripts by in situ hybridization and the expression of latent membrane protein-1 (LMP-1) and bcl-2 protein by immunohistochemistry in NSCLC patients from Taiwan, where nasopharyngeal carcinoma is endemic. | 9635525 | 1998 | ||||
|
0.100 | AlteredExpression | disease | BEFREE | While further studies with more cases are needed, this study suggests that co-expression of Bcl-2 and LMP-1 may be involved in the process of nasopharyngeal carcinoma aggravation. | 12099337 | 2002 | ||||
|
0.100 | Biomarker | disease | BEFREE | ABT-199-mediated inhibition of Bcl-2 as a potential therapeutic strategy for nasopharyngeal carcinoma. | 30017199 | 2018 | ||||
|
0.100 | AlteredExpression | disease | BEFREE | MiR-29a down-regulation is correlated with drug resistance of nasopharyngeal carcinoma cell line CNE-1 and MiR-29a up-regulation decreases Taxol resistance of nasopharyngeal carcinoma CNE-1 cells possibly via inhibiting STAT3 and Bcl-2 expression. | 29914005 | 2018 | ||||
|
0.100 | AlteredExpression | disease | BEFREE | We conclude that EBV is the important etiologic factor in NPC which may be involved in p53 and bcl-2 overexpression. | 11053650 | 2000 | ||||
|
0.100 | Biomarker | disease | BEFREE | Our studies are the first to demonstrate that PDCD4 as tumor suppressor regulated miR-184-mediated direct targeting of BCL2 and C-MYC via PI3K/AKT and JNK/C-Jun pathway attenuating cell proliferation and survival in NPC. | 24157866 | 2013 | ||||
|
0.100 | AlteredExpression | disease | BEFREE | Mangiferin induces apoptosis by regulating Bcl-2 and Bax expression in the CNE2 nasopharyngeal carcinoma cell line. | 25227792 | 2014 |