| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.100 | Biomarker | disease | BEFREE | All cases of undifferentiated NPC were positive for Bcl-2 but only one BHRF1 positive cell was identified in 1 of 39 cases of primary undifferentiated NPC. | 11505451 | 2001 | ||||
|
0.100 | AlteredExpression | disease | BEFREE | We conclude that EBV is the important etiologic factor in NPC which may be involved in p53 and bcl-2 overexpression. | 11053650 | 2000 | ||||
|
0.100 | Biomarker | disease | BEFREE | In-situ hybridization using oligonucleotide probe to EBV-encoded small RNAs (EBERs) and immunohistochemistry using monoclonal antibodies against EBV latent membrane protein 1 (LMP1), p53 protein and bcl-2 proteins were performed in 56 primary NPCs. | 10231418 | 1999 | ||||
|
0.100 | Biomarker | disease | BEFREE | Antibody against the Epstein-Barr virus BHRF1 protein, a homologue of Bcl-2, in patients with nasopharyngeal carcinoma. | 9783682 | 1998 | ||||
|
0.100 | Biomarker | disease | BEFREE | In this study, the authors investigated EBV-encoded RNA-1 (EBER1) transcripts by in situ hybridization and the expression of latent membrane protein-1 (LMP-1) and bcl-2 protein by immunohistochemistry in NSCLC patients from Taiwan, where nasopharyngeal carcinoma is endemic. | 9635525 | 1998 | ||||
|
0.100 | AlteredExpression | disease | BEFREE | However, when comparing Bcl-2 expression and known survival mean of the patients, significant differences were observed (p<0.001) so that mean survivals were 31.1, 24.4, 52.2 and 54.1 months respectively for NPC patients with -, +, ++ and Bcl-2 immunoreactivity. | 9046038 | 1997 | ||||
|
0.100 | AlteredExpression | disease | BEFREE | Of the twelve nasopharyngeal carcinomas expressing bcl-2, none showed a t(14;18) chromosome translocation. | 8732340 | 1996 | ||||
|
0.100 | AlteredExpression | disease | BEFREE | Bcl-2 proto-oncogene expression in Epstein-Barr-virus-associated nasopharyngeal carcinoma. | 8380056 | 1993 |