Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4 		0.300 Therapeutic disease CTD_human Phosphorylation of hepatic farnesoid X receptor by FGF19 signaling-activated Src maintains cholesterol levels and protects from atherosclerosis. 30996006 2019
Entrez Id: 8856
Gene Symbol: NR1I2
NR1I2 		0.300 Biomarker disease CTD_human Perinatal Bisphenol A Exposure Increases Atherosclerosis in Adult Male PXR-Humanized Mice. 29425287 2018
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker disease CTD_human Kuwanon G attenuates atherosclerosis by upregulation of LXRα-ABCA1/ABCG1 and inhibition of NFκB activity in macrophages. 29355567 2018
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker disease CTD_human Effects of Icariin on Atherosclerosis and Predicted Function Regulatory Network in ApoE Deficient Mice. 30533443 2018
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker disease CTD_human Using the Apolipoprotein E Knock-Out Mouse Model to Define Atherosclerotic Plaque Changes Induced by Low Dose Arsenic. 30376133 2018
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker disease CTD_human Perinatal Bisphenol A Exposure Increases Atherosclerosis in Adult Male PXR-Humanized Mice. 29425287 2018
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker disease CTD_human Notoginsenoside R1 attenuates atherosclerotic lesions in ApoE deficient mouse model. 24933211 2014
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker disease CTD_human Diesel exhaust particulate increases the size and complexity of lesions in atherosclerotic mice. 24330719 2013
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker disease CTD_human Copper chelation by tetrathiomolybdate inhibits vascular inflammation and atherosclerotic lesion development in apolipoprotein E-deficient mice. 22770994 2012
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker disease CTD_human Proatherogenic macrophage activities are targeted by the flavonoid quercetin. 22869926 2012
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker disease CTD_human Effects of paricalcitol and enalapril on atherosclerotic injury in mouse aortas. 20720404 2010
Entrez Id: 142
Gene Symbol: PARP1
PARP1 		0.300 Biomarker disease CTD_human Thieno[2,3-c]isoquinolin-5-one, a potent poly(ADP-ribose) polymerase inhibitor, promotes atherosclerotic plaque regression in high-fat diet-fed apolipoprotein E-deficient mice: effects on inflammatory markers and lipid content. 19124646 2009
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker disease CTD_human Thieno[2,3-c]isoquinolin-5-one, a potent poly(ADP-ribose) polymerase inhibitor, promotes atherosclerotic plaque regression in high-fat diet-fed apolipoprotein E-deficient mice: effects on inflammatory markers and lipid content. 19124646 2009
Entrez Id: 682
Gene Symbol: BSG
BSG 		0.300 Biomarker disease CTD_human Resveratrol inhibits EMMPRIN expression via P38 and ERK1/2 pathways in PMA-induced THP-1 cells. 18647594 2008
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker disease CTD_human Poly(ADP-ribose) polymerase inhibition reduces atherosclerotic plaque size and promotes factors of plaque stability in apolipoprotein E-deficient mice: effects on macrophage recruitment, nuclear factor-kappaB nuclear translocation, and foam cell death. 17438151 2007
Entrez Id: 5130
Gene Symbol: PCYT1A
PCYT1A 		0.010 Biomarker disease BEFREE None of the conventional coronary CTA high-risk features were significantly more frequent in the higher-risk (VH-IVUS defined thin-cap) compared with thick-cap fibroatheroma. 28918858 2017
Entrez Id: 105375847
Gene Symbol: CERNA3
CERNA3 		0.010 Biomarker disease BEFREE None of the conventional coronary CTA high-risk features were significantly more frequent in the higher-risk (VH-IVUS defined thin-cap) compared with thick-cap fibroatheroma. 28918858 2017
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1 		0.010 AlteredExpression disease BEFREE The amount of aromatase mRNA was significantly higher in the specimens with fibroatheroma (P<0.05) than other lesions, and was also significantly higher in the cases utilizing 1c (I.3) or 1d (PII) of exon 1, i.e. gonadal types than those utilizing 1b (I.4), i.e. fibroblasts type as the promoter (P<0.01). 11850209 2001