Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 CausalMutation disease CLINVAR A rapid and cell-free assay to test the activity of lynch syndrome-associated MSH2 and MSH6 missense variants. 22102614 2012
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 GeneticVariation disease UNIPROT Germline mutation analysis of MLH1 and MSH2 in Malaysian Lynch syndrome patients. 22371642 2012
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 GeneticVariation disease UNIPROT A rapid and cell-free assay to test the activity of lynch syndrome-associated MSH2 and MSH6 missense variants. 22102614 2012
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 CausalMutation disease CLINVAR Frequency of mutations in mismatch repair genes in a population-based study of women with ovarian cancer. 23047549 2012
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 GeneticVariation disease CLINVAR Integrated analysis of unclassified variants in mismatch repair genes. 21239990 2011
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 CausalMutation disease CLINVAR Cancer risks associated with germline mutations in MLH1, MSH2, and MSH6 genes in Lynch syndrome. 21642682 2011
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 CausalMutation disease CLINVAR Integrated analysis of unclassified variants in mismatch repair genes. 21239990 2011
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 CausalMutation disease CLINVAR Characterization of germline mutations of MLH1 and MSH2 in unrelated south American suspected Lynch syndrome individuals. 21681552 2011
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 CausalMutation disease CLINVAR Verification of the three-step model in assessing the pathogenicity of mismatch repair gene variants. 21120944 2011
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 GeneticVariation disease UNIPROT Verification of the three-step model in assessing the pathogenicity of mismatch repair gene variants. 21120944 2011
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 CausalMutation disease CLINVAR Comparative in silico analyses and experimental validation of novel splice site and missense mutations in the genes MLH1 and MSH2. 19669161 2010
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 CausalMutation disease CLINVAR Risk of urothelial bladder cancer in Lynch syndrome is increased, in particular among MSH2 mutation carriers. 20591884 2010
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 CausalMutation disease CLINVAR Current clinical criteria for Lynch syndrome are not sensitive enough to identify MSH6 mutation carriers. 20587412 2010
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 CausalMutation disease CLINVAR Evaluating Lynch syndrome in very early onset colorectal cancer probands without apparent polyposis. 19731080 2010
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 CausalMutation disease CLINVAR Major contribution from recurrent alterations and MSH6 mutations in the Danish Lynch syndrome population. 18566915 2009
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 CausalMutation disease CLINVAR A study on MSH2 and MLH1 mutations in hereditary nonpolyposis colorectal cancer families from the Basque Country, describing four new germline mutations. 19760518 2009
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 CausalMutation disease CLINVAR Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications. 19659756 2009
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 CausalMutation disease CLINVAR High frequency of exon deletions and putative founder effects in French Canadian Lynch syndrome families. 19459153 2009
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 CausalMutation disease CLINVAR Classifying MLH1 and MSH2 variants using bioinformatic prediction, splicing assays, segregation, and tumor characteristics. 19267393 2009
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 CausalMutation disease CLINVAR Mechanisms of pathogenicity in human MSH2 missense mutants. 18951462 2008
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 GeneticVariation disease UNIPROT MSH2 missense mutations and HNPCC syndrome: pathogenicity assessment in a human expression system. 18781619 2008
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 CausalMutation disease CLINVAR MSH2 missense mutations and HNPCC syndrome: pathogenicity assessment in a human expression system. 18781619 2008
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 GeneticVariation disease CLINVAR Accurate classification of MLH1/MSH2 missense variants with multivariate analysis of protein polymorphisms-mismatch repair (MAPP-MMR). 18383312 2008
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 GeneticVariation disease UNIPROT Functional analysis of HNPCC-related missense mutations in MSH2. 18822302 2008
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.600 GeneticVariation disease UNIPROT Mechanisms of pathogenicity in human MSH2 missense mutants. 18951462 2008