×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
CausalMutation
disease
CLINVAR
Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations.
28422960
2017
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
CausalMutation
disease
CLINVAR
MLH1 Ile219Val Polymorphism in Argentinean Families with Suspected Lynch Syndrome.
27606285
2016
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
GeneticVariation
disease
CLINVAR
Oligonucleotide-directed mutagenesis screen to identify pathogenic Lynch syndrome-associated MSH2 DNA mismatch repair gene variants.
26951660
2016
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
CausalMutation
disease
CLINVAR
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
26681312
2016
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
CausalMutation
disease
CLINVAR
Oligonucleotide-directed mutagenesis screen to identify pathogenic Lynch syndrome-associated MSH2 DNA mismatch repair gene variants.
26951660
2016
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
CausalMutation
disease
CLINVAR
Mismatch repair gene mutation spectrum in the Swedish Lynch syndrome population.
27601186
2016
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
CausalMutation
disease
CLINVAR
Germ-line variants identified by next generation sequencing in a panel of estrogen and cancer associated genes correlate with poor clinical outcome in Lynch syndrome patients.
26517685
2015
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
CausalMutation
disease
CLINVAR
Risk Factors Associated with Colorectal Cancer in a Subset of Patients with Mutations in MLH1 and MSH2 in Taiwan Fulfilling the Amsterdam II Criteria for Lynch Syndrome.
26053027
2015
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
CausalMutation
disease
CLINVAR
Genetic diagnosis of high-penetrance susceptibility for colorectal cancer (CRC) is achievable for a high proportion of familial CRC by exome sequencing.
25559809
2015
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
CausalMutation
disease
CLINVAR
RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease.
25525159
2015
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
CausalMutation
disease
CLINVAR
Lynch Syndrome in high risk Ashkenazi Jews in Israel.
23990280
2014
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
GeneticVariation
disease
CLINVAR
Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database.
24362816
2014
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
CausalMutation
disease
CLINVAR
Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database.
24362816
2014
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
Biomarker
disease
GENOMICS_ENGLAND
Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database.
24362816
2014
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
GeneticVariation
disease
CLINVAR
Lynch Syndrome in high risk Ashkenazi Jews in Israel.
23990280
2014
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
CausalMutation
disease
CLINVAR
High prevalence of mismatch repair deficiency in prostate cancers diagnosed in mismatch repair gene mutation carriers from the colon cancer family registry.
25117503
2014
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
CausalMutation
disease
CLINVAR
A multifactorial likelihood model for MMR gene variant classification incorporating probabilities based on sequence bioinformatics and tumor characteristics: a report from the Colon Cancer Family Registry.
22949379
2013
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
CausalMutation
disease
CLINVAR
Splice site mutations in mismatch repair genes and risk of cancer in the general population.
23329266
2013
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
CausalMutation
disease
CLINVAR
Integrative analysis of hereditary nonpolyposis colorectal cancer: the contribution of allele-specific expression and other assays to diagnostic algorithms.
24278394
2013
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
CausalMutation
disease
CLINVAR
Proteasome inhibition rescues clinically significant unstable variants of the mismatch repair protein Msh2.
23248292
2013
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
CausalMutation
disease
CLINVAR
Mutation spectrum in South American Lynch syndrome families.
24344984
2013
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
GeneticVariation
disease
CLINVAR
Integrative analysis of hereditary nonpolyposis colorectal cancer: the contribution of allele-specific expression and other assays to diagnostic algorithms.
24278394
2013
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
CausalMutation
disease
CLINVAR
Calibration of multiple in silico tools for predicting pathogenicity of mismatch repair gene missense substitutions.
22949387
2013
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
CausalMutation
disease
CLINVAR
Patients with Lynch syndrome mismatch repair gene mutations are at higher risk for not only upper tract urothelial cancer but also bladder cancer.
22883484
2013
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
CausalMutation
disease
CLINVAR
Cancer risk in Lynch Syndrome.
23604856
2013