×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
GeneticVariation
disease
CLINVAR
Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene.
20400964
2010
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
CausalMutation
disease
CLINVAR
Identification of six pathogenic RAD51C mutations via mutational screening of 1228 Danish individuals with increased risk of hereditary breast and/or ovarian cancer.
26740214
2016
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
CausalMutation
disease
CLINVAR
Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer.
27433846
2016
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
GeneticVariation
disease
UNIPROT
Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair.
24141787
2014
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
CausalMutation
disease
CLINVAR
RAD51C is a susceptibility gene for ovarian cancer.
21616938
2011
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
GeneticVariation
disease
CLINVAR
Germline mutations in DNA repair genes may predict neoadjuvant therapy response in triple negative breast patients.
27328445
2016
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
CausalMutation
disease
CLINVAR
RAD51C--a new human cancer susceptibility gene for sporadic squamous cell carcinoma of the head and neck (HNSCC).
24315737
2014
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
Biomarker
disease
GENOMICS_ENGLAND
Mutation of the RAD51C gene in a Fanconi anemia-like disorder.
20400963
2010
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
GeneticVariation
disease
CLINVAR
Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: implications for Fanconi anemia and breast cancer susceptibility.
22167183
2012
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
GeneticVariation
disease
CLINVAR
Hereditary truncating mutations of DNA repair and other genes in BRCA1/BRCA2/PALB2-negatively tested breast cancer patients.
26822949
2016
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
GeneticVariation
disease
CLINVAR
Clinical Actionability of Multigene Panel Testing for Hereditary Breast and Ovarian Cancer Risk Assessment.
26270727
2015
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
GeneticVariation
disease
CLINVAR
Mutation of the RAD51C gene in a Fanconi anemia-like disorder.
20400963
2010
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
CausalMutation
disease
CLINVAR
Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population.
26261251
2015
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
GeneticVariation
disease
CLINVAR
Germline RAD51C mutations confer susceptibility to ovarian cancer.
22538716
2012
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
CausalMutation
disease
CLINVAR
Screening for germline mutations in breast/ovarian cancer susceptibility genes in high-risk families in Israel.
26687385
2016
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
GeneticVariation
disease
CLINVAR
Germline mutation in the RAD51B gene confers predisposition to breast cancer.
24139550
2013
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
CausalMutation
disease
CLINVAR
Multiple gene sequencing for risk assessment in patients with early-onset or familial breast cancer.
26824983
2016
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
GeneticVariation
disease
CLINVAR
Mutation Analysis of the RAD51C and RAD51D Genes in High-Risk Ovarian Cancer Patients and Families from the Czech Republic.
26057125
2015
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
Biomarker
disease
CLINGEN
Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: implications for Fanconi anemia and breast cancer susceptibility.
22167183
2012
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
GeneticVariation
disease
CLINVAR
Gene panel sequencing in familial breast/ovarian cancer patients identifies multiple novel mutations also in genes others than BRCA1/2.
27616075
2017
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
CausalMutation
disease
CLINVAR
Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene.
20400964
2010
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
GeneticVariation
disease
CLINVAR
Identification of functional domains in the RAD51L2 (RAD51C) protein and its requirement for gene conversion.
12966089
2003
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
GeneticVariation
disease
CLINVAR
Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair.
24141787
2014
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
CausalMutation
disease
CLINVAR
Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer.
25452441
2015
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
0.710
GeneticVariation
disease
CLINVAR
Predominance of pathogenic missense variants in the RAD51C gene occurring in breast and ovarian cancer families.
22451500
2012