Gene: RAD51C ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. 20400964 2010
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 CausalMutation disease CLINVAR Identification of six pathogenic RAD51C mutations via mutational screening of 1228 Danish individuals with increased risk of hereditary breast and/or ovarian cancer. 26740214 2016
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 CausalMutation disease CLINVAR Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer. 27433846 2016
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease UNIPROT Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair. 24141787 2014
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 CausalMutation disease CLINVAR RAD51C is a susceptibility gene for ovarian cancer. 21616938 2011
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Germline mutations in DNA repair genes may predict neoadjuvant therapy response in triple negative breast patients. 27328445 2016
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 CausalMutation disease CLINVAR RAD51C--a new human cancer susceptibility gene for sporadic squamous cell carcinoma of the head and neck (HNSCC). 24315737 2014
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 Biomarker disease GENOMICS_ENGLAND Mutation of the RAD51C gene in a Fanconi anemia-like disorder. 20400963 2010
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: implications for Fanconi anemia and breast cancer susceptibility. 22167183 2012
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Hereditary truncating mutations of DNA repair and other genes in BRCA1/BRCA2/PALB2-negatively tested breast cancer patients. 26822949 2016
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Clinical Actionability of Multigene Panel Testing for Hereditary Breast and Ovarian Cancer Risk Assessment. 26270727 2015
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Mutation of the RAD51C gene in a Fanconi anemia-like disorder. 20400963 2010
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 CausalMutation disease CLINVAR Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population. 26261251 2015
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Germline RAD51C mutations confer susceptibility to ovarian cancer. 22538716 2012
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 CausalMutation disease CLINVAR Screening for germline mutations in breast/ovarian cancer susceptibility genes in high-risk families in Israel. 26687385 2016
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Germline mutation in the RAD51B gene confers predisposition to breast cancer. 24139550 2013
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 CausalMutation disease CLINVAR Multiple gene sequencing for risk assessment in patients with early-onset or familial breast cancer. 26824983 2016
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Mutation Analysis of the RAD51C and RAD51D Genes in High-Risk Ovarian Cancer Patients and Families from the Czech Republic. 26057125 2015
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 Biomarker disease CLINGEN Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: implications for Fanconi anemia and breast cancer susceptibility. 22167183 2012
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Gene panel sequencing in familial breast/ovarian cancer patients identifies multiple novel mutations also in genes others than BRCA1/2. 27616075 2017
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 CausalMutation disease CLINVAR Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. 20400964 2010
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Identification of functional domains in the RAD51L2 (RAD51C) protein and its requirement for gene conversion. 12966089 2003
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair. 24141787 2014
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 CausalMutation disease CLINVAR Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer. 25452441 2015
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Predominance of pathogenic missense variants in the RAD51C gene occurring in breast and ovarian cancer families. 22451500 2012