Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
0.040 Biomarker disease BEFREE This series highlights the peg-IFN-α-2b administration in Behçet's uveitis. 28700247 2019
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
0.040 Biomarker disease BEFREE Effectiveness and safety of interferon α2a as an add-on treatment for refractory Behçet's uveitis. 31105923 2019
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
0.040 Biomarker disease BEFREE Long-term low dose of IFNα-2a is useful in treating Chinese BU patients who do not respond adequately to conventional therapy. 29040035 2019
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
0.040 Biomarker disease BEFREE Interferon Alpha-2a Therapy in Patients with Refractory Behçet Uveitis. 26910383 2017
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.020 AlteredExpression disease BEFREE We observed a significant decrease in IL-10 levels in the AqH of patients with BU and a significant increase in VEGF levels in the AqH of patients with FUS compared to controls. 31065903 2019
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.020 GeneticVariation disease BEFREE RESULTS Expression levels of IL18, IFNG, IFNGR, and CRP were significantly higher in patients with active Behçet's uveitis than in control subjects (P<0.01 for all), whereas no significant differences were found in IL10 and HSP70 gene expression levels (P>0.01 for both). 29534057 2018
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
0.010 AlteredExpression disease BEFREE IL-8 levels were significantly higher in the AqH of patients with BU and FUS than in the AqH of control subjects (p < 0.001 and p < 0.001, respectively). 31065903 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.010 AlteredExpression disease BEFREE We observed a significant decrease in IL-10 levels in the AqH of patients with BU and a significant increase in VEGF levels in the AqH of patients with FUS compared to controls. 31065903 2019
Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1
0.010 Biomarker disease BEFREE <i>Conclusion</i>: IFN-α seems an effective and safe treatment option in the management of refractory BU. 31161949 2019
Entrez Id: 3595
Gene Symbol: IL12RB2
IL12RB2
0.010 GeneticVariation disease BEFREE Single-Nucleotide Polymorphisms in IL23R-IL12RB2 (rs1495965) Are Highly Prevalent in Patients with Behcet's Uveitis and Vary Between Populations. 29792538 2019
Entrez Id: 149233
Gene Symbol: IL23R
IL23R
0.010 GeneticVariation disease BEFREE Single-Nucleotide Polymorphisms in IL23R-IL12RB2 (rs1495965) Are Highly Prevalent in Patients with Behcet's Uveitis and Vary Between Populations. 29792538 2019
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
0.010 Biomarker disease BEFREE Lymphocyte proliferation induced by high-affinity peptides for HLA-B*51:01 in Behçet's uveitis. 31513650 2019
Entrez Id: 3447
Gene Symbol: IFNA13
IFNA13
0.010 Biomarker disease BEFREE <i>Conclusion</i>: IFN-α seems an effective and safe treatment option in the management of refractory BU. 31161949 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.010 AlteredExpression disease BEFREE CONCLUSIONS IL18, IFNG, IFNGR, and CRP gene expression is significantly increased in active Behçet's uveitis. 29534057 2018
Entrez Id: 3606
Gene Symbol: IL18
IL18
0.010 Biomarker disease BEFREE BACKGROUND To investigate the gene expression levels of interleukin 10 (IL10), IL18, interferon gamma (IFNG), IFN-gamma receptor (IFNGR), C-reactive protein (CRP), and heat shock protein 70 (HSP70) in patients with active Behçet's uveitis. 29534057 2018
Entrez Id: 3308
Gene Symbol: HSPA4
HSPA4
0.010 AlteredExpression disease BEFREE RESULTS Expression levels of IL18, IFNG, IFNGR, and CRP were significantly higher in patients with active Behçet's uveitis than in control subjects (P<0.01 for all), whereas no significant differences were found in IL10 and HSP70 gene expression levels (P>0.01 for both). 29534057 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.010 Biomarker disease BEFREE Tocilizumab for the Treatment of Behçet Uveitis that Failed Interferon Alpha and Anti-Tumor Necrosis Factor-Alpha Therapy. 29020500 2018
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.010 Biomarker disease BEFREE BACKGROUND To investigate the gene expression levels of interleukin 10 (IL10), IL18, interferon gamma (IFNG), IFN-gamma receptor (IFNGR), C-reactive protein (CRP), and heat shock protein 70 (HSP70) in patients with active Behçet's uveitis. 29534057 2018