Source: CURATED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 26047
Gene Symbol: CNTNAP2
CNTNAP2
0.310 Biomarker phenotype CTD_human Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits. 21962519 2011
Entrez Id: 885
Gene Symbol: CCK
CCK
0.300 Therapeutic phenotype CTD_human Behavioral evidence for the involvement of endogenous opioids in the interaction between cholecystokinin and brain dopamine systems. 3561887 1987
Entrez Id: 4880
Gene Symbol: NPPC
NPPC
0.300 Therapeutic phenotype CTD_human C-type natriuretic peptide (CNP) regulates cocaine-induced dopamine increase and immediate early gene expression in rat brain. 11860464 2001
Entrez Id: 114
Gene Symbol: ADCY8
ADCY8
0.300 Biomarker phenotype CTD_human Calmodulin-stimulated adenylyl cyclase gene deletion affects morphine responses. 16914643 2006
Entrez Id: 107
Gene Symbol: ADCY1
ADCY1
0.300 Biomarker phenotype CTD_human Calmodulin-stimulated adenylyl cyclase gene deletion affects morphine responses. 16914643 2006
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2
0.300 Biomarker phenotype CTD_human Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward. 20947769 2010
Entrez Id: 2641
Gene Symbol: GCG
GCG
0.300 Therapeutic phenotype CTD_human Central action of glucagon. 9798264 1999
Entrez Id: 4922
Gene Symbol: NTS
NTS
0.300 Therapeutic phenotype CTD_human Centrally administered neurotensin suppresses locomotor hyperactivity induced by d-amphetamine but not by scopolamine or caffeine. 3748325 1986
Entrez Id: 590
Gene Symbol: BCHE
BCHE
0.300 Therapeutic phenotype CTD_human Characterization of butyrylcholinesterase antagonism of cocaine-induced hyperactivity. 12019200 2002
Entrez Id: 885
Gene Symbol: CCK
CCK
0.300 Therapeutic phenotype CTD_human Effect of injection of CCK-8 into the nucleus caudatus on the behavior of rats. 3735805 1986
Entrez Id: 796
Gene Symbol: CALCA
CALCA
0.300 Therapeutic phenotype CTD_human Effects of calcitonin on rat extrapyramidal motor system: behavioral and biochemical data. 6293644 1982
Entrez Id: 796
Gene Symbol: CALCA
CALCA
0.300 Therapeutic phenotype CTD_human Effects of calcitonin on the brain of aged rats. 6686863 1983
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2
0.300 Biomarker phenotype CTD_human Elevated BDNF after cocaine withdrawal facilitates LTP in medial prefrontal cortex by suppressing GABA inhibition. 20826313 2010
Entrez Id: 2550
Gene Symbol: GABBR1
GABBR1
0.300 Biomarker phenotype CTD_human GABAB1 receptor subunit isoforms exert a differential influence on baseline but not GABAB receptor agonist-induced changes in mice. 16990508 2006
Entrez Id: 28964
Gene Symbol: GIT1
GIT1
0.300 Biomarker phenotype CTD_human GIT1 is associated with ADHD in humans and ADHD-like behaviors in mice. 21499268 2011
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.400 Biomarker phenotype CTD_human Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter. 18347339 2008
Entrez Id: 2353
Gene Symbol: FOS
FOS
0.300 Biomarker phenotype CTD_human Inhibiting activator protein-1 activity alters cocaine-induced gene expression and potentiates sensitization. 18355967 2008
Entrez Id: 5020
Gene Symbol: OXT
OXT
0.300 Therapeutic phenotype CTD_human Inhibition by oxytocin of methamphetamine-induced hyperactivity related to dopamine turnover in the mesolimbic region in mice. 18092152 2008
Entrez Id: 4922
Gene Symbol: NTS
NTS
0.300 Therapeutic phenotype CTD_human Interactions of neurotensin with brain dopamine systems: biochemical and behavioral studies. 6682440 1983
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
0.300 Biomarker phenotype CTD_human Interactions of serotonin (5-HT)2 receptor-targeting ligands and nicotine: locomotor activity studies in rats. 19347958 2009
Entrez Id: 3358
Gene Symbol: HTR2C
HTR2C
0.300 Therapeutic phenotype CTD_human Interactions of serotonin (5-HT)2 receptor-targeting ligands and nicotine: locomotor activity studies in rats. 19347958 2009
Entrez Id: 3558
Gene Symbol: IL2
IL2
0.300 Biomarker phenotype CTD_human Interleukin-2 enhances scopolamine-induced amnesia and hyperactivity in the mouse. 8241462 1993
Entrez Id: 27185
Gene Symbol: DISC1
DISC1
0.300 Biomarker phenotype CTD_human Misassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits. 26754951 2016
Entrez Id: 7054
Gene Symbol: TH
TH
0.300 Biomarker phenotype CTD_human Motor and learning dysfunction during postnatal development in mice defective in dopamine neuronal transmission. 9822156 1998
Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
0.300 Biomarker phenotype CTD_human Neuropeptide S reinstates cocaine-seeking behavior and increases locomotor activity through corticotropin-releasing factor receptor 1 in mice. 19339610 2009