Source: CURATED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.400 Biomarker phenotype CTD_human The role of gamma-synuclein in cocaine-induced behaviour in rats. 18588534 2008
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.400 Biomarker phenotype CTD_human Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter. 18347339 2008
Entrez Id: 26047
Gene Symbol: CNTNAP2
CNTNAP2
0.310 Biomarker phenotype CTD_human Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits. 21962519 2011
Entrez Id: 27185
Gene Symbol: DISC1
DISC1
0.300 Biomarker phenotype CTD_human Misassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits. 26754951 2016
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.300 Biomarker phenotype CTD_human New recreational drug 1-phenyl-2-(1-pyrrolidinyl)-1-pentanone (alpha-PVP) activates central nervous system via dopaminergic neuron. 24418703 2014
Entrez Id: 1812
Gene Symbol: DRD1
DRD1
0.300 Biomarker phenotype CTD_human New recreational drug 1-phenyl-2-(1-pyrrolidinyl)-1-pentanone (alpha-PVP) activates central nervous system via dopaminergic neuron. 24418703 2014
Entrez Id: 28964
Gene Symbol: GIT1
GIT1
0.300 Biomarker phenotype CTD_human GIT1 is associated with ADHD in humans and ADHD-like behaviors in mice. 21499268 2011
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2
0.300 Biomarker phenotype CTD_human Elevated BDNF after cocaine withdrawal facilitates LTP in medial prefrontal cortex by suppressing GABA inhibition. 20826313 2010
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2
0.300 Biomarker phenotype CTD_human Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward. 20947769 2010
Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
0.300 Biomarker phenotype CTD_human Neuropeptide S reinstates cocaine-seeking behavior and increases locomotor activity through corticotropin-releasing factor receptor 1 in mice. 19339610 2009
Entrez Id: 4852
Gene Symbol: NPY
NPY
0.300 Biomarker phenotype CTD_human Neuropeptide Y augments cocaine self-administration and cocaine-induced hyperlocomotion in rats. 19063928 2009
Entrez Id: 594857
Gene Symbol: NPS
NPS
0.300 Biomarker phenotype CTD_human Neuropeptide S reinstates cocaine-seeking behavior and increases locomotor activity through corticotropin-releasing factor receptor 1 in mice. 19339610 2009
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
0.300 Biomarker phenotype CTD_human Interactions of serotonin (5-HT)2 receptor-targeting ligands and nicotine: locomotor activity studies in rats. 19347958 2009
Entrez Id: 3358
Gene Symbol: HTR2C
HTR2C
0.300 Therapeutic phenotype CTD_human Interactions of serotonin (5-HT)2 receptor-targeting ligands and nicotine: locomotor activity studies in rats. 19347958 2009
Entrez Id: 2890
Gene Symbol: GRIA1
GRIA1
0.300 Biomarker phenotype CTD_human The role of hippocampal GluR1 and GluR2 receptors in manic-like behavior. 18171924 2008
Entrez Id: 2890
Gene Symbol: GRIA1
GRIA1
0.300 Biomarker phenotype CTD_human Renewed cocaine exposure produces transient alterations in nucleus accumbens AMPA receptor-mediated behavior. 19036973 2008
Entrez Id: 6623
Gene Symbol: SNCG
SNCG
0.300 Biomarker phenotype CTD_human The role of gamma-synuclein in cocaine-induced behaviour in rats. 18588534 2008
Entrez Id: 2353
Gene Symbol: FOS
FOS
0.300 Biomarker phenotype CTD_human Inhibiting activator protein-1 activity alters cocaine-induced gene expression and potentiates sensitization. 18355967 2008
Entrez Id: 5020
Gene Symbol: OXT
OXT
0.300 Therapeutic phenotype CTD_human Inhibition by oxytocin of methamphetamine-induced hyperactivity related to dopamine turnover in the mesolimbic region in mice. 18092152 2008
Entrez Id: 2891
Gene Symbol: GRIA2
GRIA2
0.300 Biomarker phenotype CTD_human The role of hippocampal GluR1 and GluR2 receptors in manic-like behavior. 18171924 2008
Entrez Id: 114
Gene Symbol: ADCY8
ADCY8
0.300 Biomarker phenotype CTD_human Calmodulin-stimulated adenylyl cyclase gene deletion affects morphine responses. 16914643 2006
Entrez Id: 2550
Gene Symbol: GABBR1
GABBR1
0.300 Biomarker phenotype CTD_human GABAB1 receptor subunit isoforms exert a differential influence on baseline but not GABAB receptor agonist-induced changes in mice. 16990508 2006
Entrez Id: 107
Gene Symbol: ADCY1
ADCY1
0.300 Biomarker phenotype CTD_human Calmodulin-stimulated adenylyl cyclase gene deletion affects morphine responses. 16914643 2006
Entrez Id: 1814
Gene Symbol: DRD3
DRD3
0.300 Therapeutic phenotype CTD_human Silencing dopamine D3-receptors in the nucleus accumbens shell in vivo induces changes in cocaine-induced hyperlocomotion. 16026479 2005
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
0.300 Biomarker phenotype CTD_human Relationship of cocaine-induced c-Fos expression to behaviors and the role of serotonin 5-HT2A receptors in cocaine-induced c-Fos expression. 16300424 2005