Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 138050
Gene Symbol: HGSNAT
HGSNAT
0.100 CausalMutation phenotype CLINVAR
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.010 Biomarker phenotype BEFREE The olfactory functioning, 123I-MIBG myocardial scintigraphy uptake and dopamine transporter single photon emission computed tomography findings did not differ between the PD patients with restlessness and those without. 30103064 2018
Entrez Id: 1791
Gene Symbol: DNTT
DNTT
0.010 Biomarker phenotype BEFREE All adult behavioral tests demonstrated that chronic TDT exposure (0.14 mg/L) led to hyperactivity and restlessness in adult zebrafish. 29874755 2018
Entrez Id: 276
Gene Symbol: AMY1A
AMY1A
0.010 AlteredExpression phenotype BEFREE Results showed that CRH administration increased plasma noradrenaline and cortisol concentrations, sAA activity, heart rate, as well as self-reported side effects (i.e. flushing in the facial area, heart rate changes, giddiness, malaise and restlessness) and stress perception, while plasma adrenaline levels remained unaffected. 28472693 2017
Entrez Id: 278
Gene Symbol: AMY1C
AMY1C
0.010 AlteredExpression phenotype BEFREE Results showed that CRH administration increased plasma noradrenaline and cortisol concentrations, sAA activity, heart rate, as well as self-reported side effects (i.e. flushing in the facial area, heart rate changes, giddiness, malaise and restlessness) and stress perception, while plasma adrenaline levels remained unaffected. 28472693 2017
Entrez Id: 277
Gene Symbol: AMY1B
AMY1B
0.010 AlteredExpression phenotype BEFREE Results showed that CRH administration increased plasma noradrenaline and cortisol concentrations, sAA activity, heart rate, as well as self-reported side effects (i.e. flushing in the facial area, heart rate changes, giddiness, malaise and restlessness) and stress perception, while plasma adrenaline levels remained unaffected. 28472693 2017
Entrez Id: 3667
Gene Symbol: IRS1
IRS1
0.010 Biomarker phenotype BEFREE Of the proteins screened in the reverse-phase protein array, we found that insulin receptor substrate 1 (IRS1) is the most highly upregulated protein in RESTless breast tumors. 26100015 2015
Entrez Id: 79727
Gene Symbol: LIN28A
LIN28A
0.010 AlteredExpression phenotype BEFREE Clinically, human RESTless breast tumors also displayed significantly enhanced LIN28A expression when compared with non-RESTless tumors. 22532168 2012
Entrez Id: 5978
Gene Symbol: REST
REST
0.010 AlteredExpression phenotype BEFREE Tumors lacking REST expression were locally invasive, consistent with the increased lymph node involvement observed in human RESTless tumors. 22532168 2012