Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
0.300 Biomarker phenotype CTD_human The sp2-iminosugar glycolipid 1-dodecylsulfonyl-5N,6O-oxomethylidenenojirimycin (DSO2-ONJ) as selective anti-inflammatory agent by modulation of hemeoxygenase-1 in Bv.2 microglial cells and retinal explants. 29191728 2018
Entrez Id: 27242
Gene Symbol: TNFRSF21
TNFRSF21
0.300 Biomarker phenotype CTD_human Death receptor 6 (DR6) antagonist antibody is neuroprotective in the mouse SOD1G93A model of amyotrophic lateral sclerosis. 24113175 2013
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.300 Therapeutic phenotype CTD_human The supplementation of FGF-2 and BDNF attenuated various parameters of inflammation, including astrocytosis, microcytosis and IL-1β expression. 21087489 2010
Entrez Id: 2247
Gene Symbol: FGF2
FGF2
0.300 Therapeutic phenotype CTD_human The supplementation of FGF-2 and BDNF attenuated various parameters of inflammation, including astrocytosis, microcytosis and IL-1β expression. 21087489 2010
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
0.300 Biomarker phenotype CTD_human ERK1/2 activation in reactive astrocytes of mice with pilocarpine-induced status epilepticus. 19402951 2009
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3
0.300 Biomarker phenotype CTD_human The ERK1/2 signaling pathway plays an important role in the early stage of reactive astrogliosis in mice with pilocarpine-induced SE. 19402951 2009
Entrez Id: 3777
Gene Symbol: KCNK3
KCNK3
0.300 Biomarker phenotype CTD_human Region-specific alterations in astroglial TWIK-related acid-sensitive K+-1 channel immunoreactivity in the rat hippocampal complex following pilocarpine-induced status epilepticus. 18671295 2008
Entrez Id: 7143
Gene Symbol: TNR
TNR
0.300 Biomarker phenotype CTD_human The parallel development of increase in focal granular TN-R immunoreactivity, reactive mossy fiber sprouting and astrogliosis in CA3 implies a role for TN-R in axon targeting and synapse formation and/or in astrocytic targeting and interactions with the ECM during lesion-induced sprouting in the adult brain. 15120744 2004
Entrez Id: 3672
Gene Symbol: ITGA1
ITGA1
0.300 Biomarker phenotype CTD_human Distribution of alpha and beta integrin subunits in the adult rat hippocampus after pilocarpine-induced neuronal cell loss, axonal reorganization and reactive astrogliosis. 12851778 2003
Entrez Id: 3688
Gene Symbol: ITGB1
ITGB1
0.300 Biomarker phenotype CTD_human Distribution of alpha and beta integrin subunits in the adult rat hippocampus after pilocarpine-induced neuronal cell loss, axonal reorganization and reactive astrogliosis. 12851778 2003
Entrez Id: 3673
Gene Symbol: ITGA2
ITGA2
0.300 Biomarker phenotype CTD_human Distribution of alpha and beta integrin subunits in the adult rat hippocampus after pilocarpine-induced neuronal cell loss, axonal reorganization and reactive astrogliosis. 12851778 2003
Entrez Id: 3690
Gene Symbol: ITGB3
ITGB3
0.300 Biomarker phenotype CTD_human Distribution of alpha and beta integrin subunits in the adult rat hippocampus after pilocarpine-induced neuronal cell loss, axonal reorganization and reactive astrogliosis. 12851778 2003
Entrez Id: 3676
Gene Symbol: ITGA4
ITGA4
0.300 Biomarker phenotype CTD_human Distribution of alpha and beta integrin subunits in the adult rat hippocampus after pilocarpine-induced neuronal cell loss, axonal reorganization and reactive astrogliosis. 12851778 2003
Entrez Id: 3678
Gene Symbol: ITGA5
ITGA5
0.300 Biomarker phenotype CTD_human Distribution of alpha and beta integrin subunits in the adult rat hippocampus after pilocarpine-induced neuronal cell loss, axonal reorganization and reactive astrogliosis. 12851778 2003
Entrez Id: 3691
Gene Symbol: ITGB4
ITGB4
0.300 Biomarker phenotype CTD_human Distribution of alpha and beta integrin subunits in the adult rat hippocampus after pilocarpine-induced neuronal cell loss, axonal reorganization and reactive astrogliosis. 12851778 2003
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
0.300 Biomarker phenotype CTD_human Alterations of the neocortical GABAergic system in the pilocarpine model of temporal lobe epilepsy: neuronal damage and immunocytochemical changes in chronic epileptic rats. 12183020 2002
Entrez Id: 2918
Gene Symbol: GRM8
GRM8
0.300 Biomarker phenotype CTD_human Metabotropic glutamate receptor 8 in the rat hippocampus after pilocarpine induced status epilepticus. 11226630 2001
Entrez Id: 2896
Gene Symbol: GRN
GRN
0.100 Biomarker phenotype HPO
Entrez Id: 54664
Gene Symbol: TMEM106B
TMEM106B
0.100 Biomarker phenotype HPO
Entrez Id: 103
Gene Symbol: ADAR
ADAR
0.100 Biomarker phenotype HPO
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
0.100 Biomarker phenotype HPO
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1
0.100 Biomarker phenotype HPO
Entrez Id: 54209
Gene Symbol: TREM2
TREM2
0.100 Biomarker phenotype HPO
Entrez Id: 7249
Gene Symbol: TSC2
TSC2
0.100 Biomarker phenotype HPO
Entrez Id: 92335
Gene Symbol: STRADA
STRADA
0.100 Biomarker phenotype HPO