Gene: BRAF ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		0.080 Biomarker disease BEFREE We identified novel ALK fusions in a neuroblastoma (BEND5-ALK) and an astrocytoma (PPP1CB-ALK), novel BRAF fusions in an astrocytoma (BCAS1-BRAF) and a ganglioglioma (TMEM106B-BRAF), and a novel PAX3-GLI2 fusion in a rhabdomyosarcoma. 28069802 2017
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		0.080 GeneticVariation disease BEFREE A case of high-grade astrocytoma with BRAF and ATRX mutations following a long-standing course over two decades. 28185325 2017
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		0.080 GeneticVariation disease BEFREE Thus BRAF V600E mutation is common in desmoplastic non-infantile astrocytoma/ganglioglioma, but does not affect the prognosis. 29902580 2018
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		0.080 GeneticVariation disease BEFREE The BT-40 low-grade childhood astrocytoma xenograft model expresses mutated BRAF(V600E) and is highly sensitive to the MEK inhibitor selumetinib (AZD6244). 24132923 2013
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		0.080 GeneticVariation disease BEFREE BRAF V600E mutation was observed both in epithelioid tumor cells and in diffusely infiltrating less atypical astrocytoma cells. 24354918 2014
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		0.080 GeneticVariation disease BEFREE We report four cases of high-grade astrocytoma with a BRAF V600E mutation, ATRX inactivation, and CDKN2A/B homozygous deletion. 30972500 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		0.080 GeneticVariation disease BEFREE Inhibition of MEK confers hypersensitivity to X-radiation in the context of BRAF mutation in a model of childhood astrocytoma. 25981859 2015
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		0.080 GeneticVariation disease BEFREE The BRAF(V600E) inhibitor PLX4720 significantly increased survival of mice after intracranial transplant of genetically relevant murine or human astrocytoma cells. 22586120 2012