Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.050 | GeneticVariation | BEFREE | We report four cases of high-grade astrocytoma with a BRAF V600E mutation, ATRX inactivation, and CDKN2A/B homozygous deletion. | 30972500 | 2019 |
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0.050 | GeneticVariation | BEFREE | We report four cases of high-grade astrocytoma with a BRAF V600E mutation, ATRX inactivation, and CDKN2A/B homozygous deletion. | 30972500 | 2019 |
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0.050 | GeneticVariation | BEFREE | Thus BRAF V600E mutation is common in desmoplastic non-infantile astrocytoma/ganglioglioma, but does not affect the prognosis. | 29902580 | 2018 |
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0.050 | GeneticVariation | BEFREE | Thus BRAF V600E mutation is common in desmoplastic non-infantile astrocytoma/ganglioglioma, but does not affect the prognosis. | 29902580 | 2018 |
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0.050 | GeneticVariation | BEFREE | BRAF V600E mutation was observed both in epithelioid tumor cells and in diffusely infiltrating less atypical astrocytoma cells. | 24354918 | 2014 |
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0.050 | GeneticVariation | BEFREE | BRAF V600E mutation was observed both in epithelioid tumor cells and in diffusely infiltrating less atypical astrocytoma cells. | 24354918 | 2014 |
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0.050 | GeneticVariation | BEFREE | The BT-40 low-grade childhood astrocytoma xenograft model expresses mutated BRAF(V600E) and is highly sensitive to the MEK inhibitor selumetinib (AZD6244). | 24132923 | 2013 |
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0.050 | GeneticVariation | BEFREE | The BT-40 low-grade childhood astrocytoma xenograft model expresses mutated BRAF(V600E) and is highly sensitive to the MEK inhibitor selumetinib (AZD6244). | 24132923 | 2013 |
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0.050 | GeneticVariation | BEFREE | The BRAF(V600E) inhibitor PLX4720 significantly increased survival of mice after intracranial transplant of genetically relevant murine or human astrocytoma cells. | 22586120 | 2012 |
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0.050 | GeneticVariation | BEFREE | The BRAF(V600E) inhibitor PLX4720 significantly increased survival of mice after intracranial transplant of genetically relevant murine or human astrocytoma cells. | 22586120 | 2012 |