Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2289
Gene Symbol: FKBP5
FKBP5
0.020 GeneticVariation disease BEFREE Two FKBP5 alleles (rs3798347-T and rs10947563-A) were more frequent in BPD subjects with history of physical abuse and emotional neglect and two CRHR2 variants (rs4722999-C and rs12701020-C) in BPD subjects with sexual and physical abuse. 26182893 2016
Entrez Id: 1395
Gene Symbol: CRHR2
CRHR2
0.020 GeneticVariation disease BEFREE Two FKBP5 alleles (rs3798347-T and rs10947563-A) were more frequent in BPD subjects with history of physical abuse and emotional neglect and two CRHR2 variants (rs4722999-C and rs12701020-C) in BPD subjects with sexual and physical abuse. 26182893 2016
Entrez Id: 1395
Gene Symbol: CRHR2
CRHR2
0.020 GeneticVariation disease BEFREE Polymorphisms within CRHR1 and CRHR2 genes interacted with both childhood sexual abuse and emotional neglect to influence IGT performance. 23177644 2013
Entrez Id: 2289
Gene Symbol: FKBP5
FKBP5
0.020 Biomarker disease BEFREE FKBP5 and emotional neglect interact to predict individual differences in amygdala reactivity. 22979952 2012
Entrez Id: 5021
Gene Symbol: OXTR
OXTR
0.010 GeneticVariation disease BEFREE We investigated, in a cross-sectional study, the associations between EN, (epi)genetic variation in the OXT receptor (OXTR) gene, and amygdalar and hippocampal volumes, two brain regions implicated in emotional processing. 30806136 2019
Entrez Id: 91544
Gene Symbol: UBXN11
UBXN11
0.010 Biomarker disease BEFREE Furthermore, SOC-R significantly mediated the relationship for general mental health (GMH) and satisfaction with life (SWL) with childhood emotional neglect (GMH: <i>b</i> = -0.056, 95% BCa CI [-0.126, -0.002]; SWL: <i>b</i> = -0.043, 95% BCa CI [-0.088, -0.004]), childhood physical neglect (GMH: <i>b</i> = -0.100, 95% BCa CI [-0.232, -0.002]; SWL: <i>b</i> = -0.081, 95% BCa CI [-0.181, -0.002]), and chronic stress (GMH: <i>b</i> = -0.052, 95% BCa CI [-0.100, -0.001]; SWL: <i>b</i> = -0.055, 95% BCa CI [-0.097, -0.020]). 30186189 2018
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.010 AlteredExpression disease BEFREE The serum BDNF level of self-harming adolescents who used the self-cutting method was significantly lower than that of other groups, and serum BDNF levels decreased with the increase in the emotional neglect and abuse severity of self-harming adolescents during childhood. 29017139 2017
Entrez Id: 3060
Gene Symbol: HCRT
HCRT
0.010 AlteredExpression disease BEFREE There were positive correlations between serum orexin levels and CTQ total score and between orexin levels and some CTQ subscale scores, such as physical and emotional neglect, in patients. 27043067 2017
Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
0.010 GeneticVariation disease BEFREE Polymorphisms within CRHR1 and CRHR2 genes interacted with both childhood sexual abuse and emotional neglect to influence IGT performance. 23177644 2013