Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 335
Gene Symbol: APOA1
APOA1
0.300 Biomarker phenotype CTD_human Common variants in genes related to lipid and energy metabolism are associated with weight loss after an intervention in overweight/obese adolescents. 25137265 2014
Entrez Id: 79068
Gene Symbol: FTO
FTO
0.300 Biomarker phenotype CTD_human Common variants in genes related to lipid and energy metabolism are associated with weight loss after an intervention in overweight/obese adolescents. 25137265 2014
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.300 Biomarker phenotype CTD_human Common variants in genes related to lipid and energy metabolism are associated with weight loss after an intervention in overweight/obese adolescents. 25137265 2014
Entrez Id: 1071
Gene Symbol: CETP
CETP
0.300 Biomarker phenotype CTD_human Common variants in genes related to lipid and energy metabolism are associated with weight loss after an intervention in overweight/obese adolescents. 25137265 2014
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.020 AlteredExpression phenotype BEFREE Hs-CRP, IL-6, and M30 levels also increased with adolescent obesity. 31120986 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.020 Biomarker phenotype BEFREE Our findings showed that suPAR, IL-6, fibrinogen, hsCRP and leptin were significantly higher in the obese individuals than those of controls. suPAR may be a good novel biomarker for systemic subclinical inflammation and immune activation linked to adolescent obesity. 28749394 2017
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.010 AlteredExpression phenotype BEFREE Hs-CRP, IL-6, and M30 levels also increased with adolescent obesity. 31120986 2019
Entrez Id: 2641
Gene Symbol: GCG
GCG
0.010 Biomarker phenotype BEFREE Fructose consumption may contribute to the hyperinsulinemic phenotype of adolescent obesity through a GLP-1-mediated mechanism. 30938760 2019
Entrez Id: 4170
Gene Symbol: MCL1
MCL1
0.010 Biomarker phenotype BEFREE Obesity in Adolescence Predicts Lower Educational Attainment and Income in Adulthood: The Project EAT Longitudinal Study. 30226010 2018
Entrez Id: 4544
Gene Symbol: MTNR1B
MTNR1B
0.010 GeneticVariation phenotype BEFREE Results No statistically significant association was observed between MTNR1B gene rs8192552/rs10830963 polymorphisms and adolescent obesity. 29726288 2018
Entrez Id: 79191
Gene Symbol: IRX3
IRX3
0.010 Biomarker phenotype BEFREE IRX3 is a genetic modifier for birth weight, adolescent obesity and transaminase metabolism. 28316138 2018
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.010 Biomarker phenotype BEFREE Our findings showed that suPAR, IL-6, fibrinogen, hsCRP and leptin were significantly higher in the obese individuals than those of controls. suPAR may be a good novel biomarker for systemic subclinical inflammation and immune activation linked to adolescent obesity. 28749394 2017
Entrez Id: 5340
Gene Symbol: PLG
PLG
0.010 AlteredExpression phenotype BEFREE Serum levels of soluble urokinase plasminogen activator receptor as a new inflammatory marker in adolescent obesity. 28749394 2017
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.010 Biomarker phenotype BEFREE This study was conducted to evaluate the role of suPAR, and its association with leptin, adiponectin, interleukin-6 (IL-6), high-sensitive C-reactive protein (hsCRP) and fibrinogen in adolescent obesity. 28749394 2017
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
0.010 Biomarker phenotype BEFREE Potential interactions between HLA-DRB1*15 and absence of HLA-A*02, respectively, and both childhood and adolescent obesity were evaluated by calculating the attributable proportion due to interaction. 26362895 2016
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
0.010 Biomarker phenotype BEFREE Potential interactions between HLA-DRB1*15 and absence of HLA-A*02, respectively, and both childhood and adolescent obesity were evaluated by calculating the attributable proportion due to interaction. 26362895 2016
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
0.010 Biomarker phenotype BEFREE Opioid receptor mu 1 gene, fat intake and obesity in adolescence. 23337944 2014
Entrez Id: 80339
Gene Symbol: PNPLA3
PNPLA3
0.010 GeneticVariation phenotype BEFREE Polymorphisms in the five genes of the adiponutrin gene family were selected and genotyped using the Sequenom platform in a childhood and adolescent obesity case-control study. 19390624 2009
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.010 GeneticVariation phenotype BEFREE Interestingly, physical exercise and lack of obesity in adolescence have been associated with significantly delayed breast cancer onset for Ashkenazi Jewish women carrying BRCA1 gene mutations. 17620310 2008