×
Entrez Id: 3815
Gene Symbol: KIT
KIT
0.100
GeneticVariation
group
BEFREE
KIT and PDGFRA mutations in gastrointestinal stromal tumors) and (ii) sarcomas displaying multiple, complex karyotypic abnormalities with no specific pattern, including leiomyo-sarcoma, and pleomorphic liposarcoma.20490332 2010
×
Entrez Id: 2521
Gene Symbol: FUS
FUS
0.100
AlteredExpression
group
BEFREE
FUS1 mRNA expression was detected in all sarcoma cell lines, all benign BSTs and healthy tissues, and almost all sarcoma tissues.21273575 2011
×
Entrez Id: 11334
Gene Symbol: TUSC2
TUSC2
0.010
AlteredExpression
group
BEFREE
FUS1 mRNA expression was detected in all sarcoma cell lines, all benign BSTs and healthy tissues, and almost all sarcoma tissues.21273575 2011
×
Entrez Id: 3835
Gene Symbol: KIF22
KIF22
0.010
Biomarker
group
BEFREE
OBP -301 was cytopathic for 12 sarcoma cell lines but not for the non-CAR-expressing OUMS-27 and NMFH-1 cells.21325287 2011
×
Entrez Id: 29991
Gene Symbol: OBP2A
OBP2A
0.010
Biomarker
group
BEFREE
OBP -301 was cytopathic for 12 sarcoma cell lines but not for the non-CAR-expressing OUMS-27 and NMFH-1 cells.21325287 2011
×
Entrez Id: 857
Gene Symbol: CAV1
CAV1
0.030
Biomarker
group
BEFREE
Caveolin-1 in sarcomas : friend or foe?21471610 2011
×
Entrez Id: 57124
Gene Symbol: CD248
CD248
0.060
Biomarker
group
BEFREE
Endosialin emerged recently as a potential therapeutic target for sarcoma .21701770 2011
×
Entrez Id: 2130
Gene Symbol: EWSR1
EWSR1
0.100
Biomarker
group
BEFREE
EWS fusions with non-ETS transcription factor family members have been described in sarcomas that are clearly distinct from Ewing's sarcoma.21872822 2011
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.100
Biomarker
group
BEFREE
KRAS , the human homolog of the Kirsten rat sarcoma -2 virus oncogene, encodes a main downstream signaling molecule in the EGFR pathway.22386733 2012
×
Entrez Id: 1436
Gene Symbol: CSF1R
CSF1R
0.030
Biomarker
group
BEFREE
FMS , first discovered as the oncogene responsible for Feline McDonough Sarcoma , is a type III receptor tyrosine kinase that binds to the macrophage or monocyte colony-stimulating factor (M-CSF or CSF-1).22434539 2013
×
Entrez Id: 2130
Gene Symbol: EWSR1
EWSR1
0.100
Biomarker
group
BEFREE
EWSR1 -CREB1 and EWSR1 -ATF1 are gene fusions of which one or both have now been consistently described in 5 histopathologically and behaviorally diverse neoplasms: angiomatoid fibrous histiocytoma, conventional clear cell sarcoma (of tendons and aponeuroses), clear cell sarcoma-like tumor of the gastrointestinal tract, hyalinizing clear cell carcinoma of the salivary gland, and primary pulmonary myxoid sarcoma .22510762 2012
×
Entrez Id: 6790
Gene Symbol: AURKA
AURKA
0.010
Biomarker
group
BEFREE
AURKA was among the 19 genes common to the top 50 features of the high-risk phenotype and a 67-gene signature called the complexity index in sarcomas .22588468 2012
×
Entrez Id: 6760
Gene Symbol: SS18
SS18
0.100
Biomarker
group
BEFREE
SYT -SSX is thought to be responsible for sarcoma initiation and development.22594313 2012
×
Entrez Id: 6857
Gene Symbol: SYT1
SYT1
0.100
Biomarker
group
BEFREE
SYT -SSX is thought to be responsible for sarcoma initiation and development.22594313 2012
×
Entrez Id: 221895
Gene Symbol: JAZF1
JAZF1
0.040
Biomarker
group
BEFREE
JAZF1 rearrangement was detected in 32% of low-grade endometrial stromal sarcomas and in none of the undifferentiated sarcomas .22918161 2013
×
Entrez Id: 7108
Gene Symbol: TM7SF2
TM7SF2
0.010
AlteredExpression
group
BEFREE
Ang-(1 -7) has clinical and pre-clinical activity for vascular sarcomas that is linked to reduced HIF-1α and PlGF expression.22963500 2012
×
Entrez Id: 284
Gene Symbol: ANGPT1
ANGPT1
0.010
AlteredExpression
group
BEFREE
Ang-(1 -7) has clinical and pre-clinical activity for vascular sarcomas that is linked to reduced HIF-1α and PlGF expression.22963500 2012
×
Entrez Id: 6323
Gene Symbol: SCN1A
SCN1A
0.010
AlteredExpression
group
BEFREE
NAC1 , a BTB/POZ protein overexpressed in uterine sarcomas .22993327 2012
×
Entrez Id: 112939
Gene Symbol: NACC1
NACC1
0.010
AlteredExpression
group
BEFREE
NAC1 , a BTB/POZ protein overexpressed in uterine sarcomas .22993327 2012
×
Entrez Id: 8148
Gene Symbol: TAF15
TAF15
0.030
Biomarker
group
BEFREE
TAF15 (formerly TAFII68 ) is a member of the FET (FUS, EWS, TAF15 ) family of RNA- and DNA-binding proteins whose genes are frequently translocated in sarcomas .23128393 2013
×
Entrez Id: 10149
Gene Symbol: ADGRG2
ADGRG2
0.010
AlteredExpression
group
BEFREE
G-protein coupled receptor 64 (GPR64 ), an orphan receptor with normal expression restricted to human epididymis is specifically over-expressed in ES among sarcoma , but also up-regulated in a number of carcinomas derived from prostate, kidney or lung.23338946 2013
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.090
AlteredExpression
group
BEFREE
Cyclin D1 was the most sensitive marker for high-grade endometrial sarcomas with YWHAE rearrangement.23599159 2013
×
Entrez Id: 23152
Gene Symbol: CIC
CIC
0.100
Biomarker
group
BEFREE
CIC -DUX4 sarcoma represents a novel translocation-associated sarcoma with distinctive histopathologic features and rapid disease progression.23887164 2013
×
Entrez Id: 3855
Gene Symbol: KRT7
KRT7
0.020
AlteredExpression
group
BEFREE
Cytokeratin-7 , thyroid transcription factor (TTF)1, napsin A, thymidylate synthase and excision repair cross-complementing rodent repair deficiency complementation group-1 expression, anaplastic lymphoma kinase rearrangements as well as epidermal growth factor receptor (EGFR), V-Ki-ras2 Kirsten rat sarcoma viral oncogene homologue (KRAS) and v-Raf murine sarcoma viral oncogene homologue B1 (BRAF) mutations were analysed.23988776 2014
SLC25A16
0.010
Biomarker
group
BEFREE
GDC -0449 in patients with advanced chondrosarcomas: a French Sarcoma Group/US and French National Cancer Institute Single-Arm Phase II Collaborative Study.24170610 2013