Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.510 Biomarker disease CTD_human p53 mutants cooperate with HIF-1 in transcriptional regulation of extracellular matrix components to promote tumor progression. 30381462 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.510 Biomarker disease CTD_human Genomic landscape of cutaneous T cell lymphoma. 26192916 2015
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.510 Biomarker disease CTD_human The oncoprotein HBXIP modulates the feedback loop of MDM2/p53 to enhance the growth of breast cancer. 26229107 2015
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.510 Biomarker disease CTD_human Exquisite sensitivity of TP53 mutant and basal breast cancers to a dose-dense epirubicin-cyclophosphamide regimen. 17388661 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.510 Biomarker disease CTD_human Evaluation of the prognostic and predictive value of p53 and Bcl-2 in breast cancer patients participating in a randomized study with dose-dense sequential adjuvant chemotherapy. 16968874 2006
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.510 Biomarker disease CTD_human Worse survival for TP53 (p53)-mutated breast cancer patients receiving adjuvant CMF. 15802278 2005
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.510 Biomarker disease CTD_mouse Frequent mutations of the Trp53, Hras1 and beta-catenin (Catnb) genes in 1,3-butadiene-induced mammary adenocarcinomas in B6C3F1 mice. 12165863 2002
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.510 GeneticVariation disease BEFREE Multiple mutations of the p53 gene in human mammary carcinoma. 10606817 1999
Entrez Id: 4312
Gene Symbol: MMP1
MMP1 		0.500 Biomarker disease CTD_mouse Combined deletion of Pten and p53 in mammary epithelium accelerates triple-negative breast cancer with dependency on eEF2K. 25330770 2014
Entrez Id: 4312
Gene Symbol: MMP1
MMP1 		0.500 Biomarker disease CTD_human Matrix metalloproteinase Mmp-1a is dispensable for normal growth and fertility in mice and promotes lung cancer progression by modulating inflammatory responses. 23548910 2013
Entrez Id: 167465
Gene Symbol: ZNF366
ZNF366 		0.500 Biomarker disease CTD_mouse Clinical significance of the nuclear receptor co-regulator DC-SCRIPT in breast cancer: an independent retrospective validation study. 21122099 2010
Entrez Id: 167465
Gene Symbol: ZNF366
ZNF366 		0.500 Biomarker disease CTD_human DC-SCRIPT: nuclear receptor modulation and prognostic significance in primary breast cancer. 20008677 2010
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.370 Therapeutic disease CTD_human Prognostic Significance of VEGFC and VEGFR1 mRNA Expression According to HER2 Status in Breast Cancer: A Study of Primary Tumors from Patients with High-risk Early Breast Cancer Participating in a Randomized Hellenic Cooperative Oncology Group Trial. 26124351 2015
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.370 Biomarker disease CTD_human Prognostic Significance of VEGFC and VEGFR1 mRNA Expression According to HER2 Status in Breast Cancer: A Study of Primary Tumors from Patients with High-risk Early Breast Cancer Participating in a Randomized Hellenic Cooperative Oncology Group Trial. 26124351 2015
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.370 Biomarker disease CTD_human CDK4/6 inhibition provides a potent adjunct to Her2-targeted therapies in preclinical breast cancer models. 25221644 2014
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.370 Therapeutic disease CTD_human Molecular profiling of single circulating tumor cells with diagnostic intention. 25358515 2014
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.370 Therapeutic disease CTD_human CDK4/6 inhibition provides a potent adjunct to Her2-targeted therapies in preclinical breast cancer models. 25221644 2014
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.370 Biomarker disease CTD_human Molecular profiling of single circulating tumor cells with diagnostic intention. 25358515 2014
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.370 Therapeutic disease CTD_human In situ detection of HER2:HER2 and HER2:HER3 protein-protein interactions demonstrates prognostic significance in early breast cancer. 21638049 2012
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.370 Therapeutic disease CTD_human Multiple roles of cyclin-dependent kinase 4/6 inhibitors in cancer therapy. 22302033 2012
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.370 Biomarker disease CTD_human Multiple roles of cyclin-dependent kinase 4/6 inhibitors in cancer therapy. 22302033 2012
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.370 Biomarker disease CTD_human In situ detection of HER2:HER2 and HER2:HER3 protein-protein interactions demonstrates prognostic significance in early breast cancer. 21638049 2012
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.370 Therapeutic disease CTD_human Suppression of Heregulin-β1/HER2-Modulated Invasive and Aggressive Phenotype of Breast Carcinoma by Pterostilbene via Inhibition of Matrix Metalloproteinase-9, p38 Kinase Cascade and Akt Activation. 19617202 2011
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.370 Biomarker disease CTD_human Suppression of Heregulin-β1/HER2-Modulated Invasive and Aggressive Phenotype of Breast Carcinoma by Pterostilbene via Inhibition of Matrix Metalloproteinase-9, p38 Kinase Cascade and Akt Activation. 19617202 2011
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.370 Biomarker disease CTD_human Correlation of microarray-based breast cancer molecular subtypes and clinical outcomes: implications for treatment optimization. 21501481 2011