Source: ALL
Associated Disease N. genes N. variants N. of shared genes JI g p-value g N. of shared variants JI v p-value v
CUI: C4553976
Disease: Urinary Urgency, CTCAE 5
Urinary Urgency, CTCAE 5 		34 0 34 0.85 0 0
CUI: C0240341
Disease: Micrographia
Micrographia 		14 0 10 0.23 0 0
CUI: C1846865
Disease: Substantia nigra gliosis
Substantia nigra gliosis 		14 0 10 0.23 0 0
CUI: C3805715
Disease: Short stepped shuffling gait
Short stepped shuffling gait 		16 0 10 0.22 0 0
CUI: C1843663
Disease: Urinary bladder sphincter dysfunction
Urinary bladder sphincter dysfunction 		28 0 12 0.21 0 0
CUI: C1849134
Disease: Impaired vibration sensation in the lower limbs
Impaired vibration sensation in the lower limbs 		39 4 13 0.20 1 0.25
CUI: C1271100
Disease: Lower limb spasticity
Lower limb spasticity 		43 0 13 0.19 0 0
CUI: C0241700
Disease: Voice Fatigue
Voice Fatigue 		20 0 9 0.18 0 0
CUI: C0751602
Disease: Hereditary Autosomal Dominant Spastic Paraplegia
Hereditary Autosomal Dominant Spastic Paraplegia 		27 0 10 0.18 0 0
CUI: C0234379
Disease: Resting Tremor
Resting Tremor 		57 0 14 0.17 0 0
CUI: C1843921
Disease: Postural instability
Postural instability 		60 0 14 0.16 0 0
CUI: C0231687
Disease: Spastic gait
Spastic gait 		62 0 14 0.16 0 0
CUI: C0240735
Disease: Personality Change
Personality Change 		43 0 11 0.15 0 0
CUI: C1846566
Disease: Degeneration of the lateral corticospinal tracts
Degeneration of the lateral corticospinal tracts 		21 0 8 0.15 0 0
CUI: C1836296
Disease: Muscle Weakness Lower Limb
Muscle Weakness Lower Limb 		74 0 14 0.14 0 0
CUI: C0042024
Disease: Urinary Incontinence
Urinary Incontinence 		151 0 23 0.14 0 0
CUI: C1850496
Disease: Neuronal loss in central nervous system
Neuronal loss in central nervous system 		37 0 9 0.13 0 0
CUI: C0238651
Disease: Ankle clonus
Ankle clonus 		32 5 8 0.12 1 0.20
CUI: C1846017
Disease: Progressive pes cavus
Progressive pes cavus 		9 0 5 0.11 0 0
CUI: C1866855
Disease: Spastic paraplegia 4, autosomal dominant
Spastic paraplegia 4, autosomal dominant 		10 0 5 0.11 0 0
CUI: C0037773
Disease: Spastic Paraplegia, Hereditary
Spastic Paraplegia, Hereditary 		123 0 16 0.11 0 0
CUI: C0424448
Disease: Mask-like facies
Mask-like facies 		64 0 10 0.11 0 0
CUI: C0747251
Disease: Progressive spastic paraparesis
Progressive spastic paraparesis 		14 0 5 0.10 0 0
CUI: C1836696
Disease: Lower limb hyperreflexia
Lower limb hyperreflexia 		38 6 7 9.9E-02 1 0.17
CUI: C1843175
Disease: Hyperreflexia in upper limbs
Hyperreflexia in upper limbs 		16 0 5 9.8E-02 0 0