Source: ALL
Associated Disease N. genes N. variants N. of shared genes JI g p-value g N. of shared variants JI v p-value v
CUI: C0231687
Disease: Spastic gait
Spastic gait 		62 0 23 0.28 0 0
CUI: C1273957
Disease: Upper limb spasticity
Upper limb spasticity 		14 0 10 0.21 0 0
CUI: C1843663
Disease: Urinary bladder sphincter dysfunction
Urinary bladder sphincter dysfunction 		28 0 12 0.20 0 0
CUI: C4553976
Disease: Urinary Urgency, CTCAE 5
Urinary Urgency, CTCAE 5 		34 0 13 0.20 0 0
CUI: C1836296
Disease: Muscle Weakness Lower Limb
Muscle Weakness Lower Limb 		74 15 19 0.19 1 5.3E-02
CUI: C0238651
Disease: Ankle clonus
Ankle clonus 		32 0 12 0.19 0 0
CUI: C1849134
Disease: Impaired vibration sensation in the lower limbs
Impaired vibration sensation in the lower limbs 		39 0 13 0.19 0 0
CUI: C0085606
Disease: Urgency of micturition
Urgency of micturition 		40 0 13 0.19 0 0
CUI: C0037773
Disease: Spastic Paraplegia, Hereditary
Spastic Paraplegia, Hereditary 		123 41 25 0.18 1 2.2E-02
CUI: C0037772
Disease: Spastic Paraplegia
Spastic Paraplegia 		144 0 28 0.18 0 0
CUI: C0751602
Disease: Hereditary Autosomal Dominant Spastic Paraplegia
Hereditary Autosomal Dominant Spastic Paraplegia 		27 0 10 0.17 0 0
CUI: C0037771
Disease: Paraparesis, Spastic
Paraparesis, Spastic 		75 37 16 0.16 2 5.0E-02
CUI: C0042024
Disease: Urinary Incontinence
Urinary Incontinence 		151 14 25 0.15 2 0.12
CUI: C0751603
Disease: Autosomal Recessive Hereditary Spastic Paraplegia
Autosomal Recessive Hereditary Spastic Paraplegia 		20 0 8 0.15 0 0
CUI: C0034935
Disease: Babinski Reflex
Babinski Reflex 		218 0 31 0.13 0 0
CUI: C0393556
Disease: Complicated hereditary spastic paraplegia
Complicated hereditary spastic paraplegia 		16 0 7 0.13 0 0
CUI: C1836696
Disease: Lower limb hyperreflexia
Lower limb hyperreflexia 		38 0 9 0.12 0 0
CUI: C1846566
Disease: Degeneration of the lateral corticospinal tracts
Degeneration of the lateral corticospinal tracts 		21 0 7 0.12 0 0
CUI: C0030486
Disease: Paraplegia
Paraplegia 		59 0 10 0.11 0 0
CUI: C0393555
Disease: Pure hereditary spastic paraplegia
Pure hereditary spastic paraplegia 		9 0 5 0.11 0 0
CUI: C0034152
Disease: Henoch-Schoenlein Purpura
Henoch-Schoenlein Purpura 		198 0 23 0.11 0 0
CUI: C0431370
Disease: Atrophy of corpus callosum
Atrophy of corpus callosum 		21 0 6 0.10 0 0
CUI: C2931356
Disease: Spastic paraplegia type 5A, recessive
Spastic paraplegia type 5A, recessive 		13 0 5 9.8E-02 0 0
CUI: C0039273
Disease: Talipes cavus
Talipes cavus 		213 0 22 9.4E-02 0 0
CUI: C1843175
Disease: Hyperreflexia in upper limbs
Hyperreflexia in upper limbs 		16 0 5 9.3E-02 0 0