Source: ALL
Associated Disease N. genes N. variants N. of shared genes JI g p-value g N. of shared variants JI v p-value v
CUI: C0231687
Disease: Spastic gait
Spastic gait 		62 0 20 0.25 0 0
CUI: C1846566
Disease: Degeneration of the lateral corticospinal tracts
Degeneration of the lateral corticospinal tracts 		21 0 10 0.20 0 0
CUI: C0085606
Disease: Urgency of micturition
Urgency of micturition 		40 1 13 0.20 1 0.25
CUI: C4553976
Disease: Urinary Urgency, CTCAE 5
Urinary Urgency, CTCAE 5 		34 0 12 0.20 0 0
CUI: C1843663
Disease: Urinary bladder sphincter dysfunction
Urinary bladder sphincter dysfunction 		28 0 11 0.20 0 0
CUI: C1836296
Disease: Muscle Weakness Lower Limb
Muscle Weakness Lower Limb 		74 0 18 0.19 0 0
CUI: C1271100
Disease: Lower limb spasticity
Lower limb spasticity 		43 0 13 0.19 0 0
CUI: C0751602
Disease: Hereditary Autosomal Dominant Spastic Paraplegia
Hereditary Autosomal Dominant Spastic Paraplegia 		27 0 10 0.18 0 0
CUI: C0238651
Disease: Ankle clonus
Ankle clonus 		32 5 10 0.16 1 0.12
CUI: C1846017
Disease: Progressive pes cavus
Progressive pes cavus 		9 0 6 0.14 0 0
CUI: C0037772
Disease: Spastic Paraplegia
Spastic Paraplegia 		144 0 22 0.14 0 0
CUI: C1836696
Disease: Lower limb hyperreflexia
Lower limb hyperreflexia 		38 6 9 0.13 1 0.11
CUI: C0454596
Disease: Dysarthria, Spastic
Dysarthria, Spastic 		30 0 8 0.13 0 0
CUI: C0037773
Disease: Spastic Paraplegia, Hereditary
Spastic Paraplegia, Hereditary 		123 0 18 0.12 0 0
CUI: C4021585
Disease: Impaired distal proprioception
Impaired distal proprioception 		7 1 5 0.12 1 0.25
CUI: C1263857
Disease: Peripheral axonal neuropathy
Peripheral axonal neuropathy 		94 0 14 0.12 0 0
CUI: C1836451
Disease: Distal lower limb amyotrophy
Distal lower limb amyotrophy 		29 0 7 0.11 0 0
CUI: C1836450
Disease: Distal lower limb muscle weakness
Distal lower limb muscle weakness 		49 0 9 0.11 0 0
CUI: C1855483
Disease: Progressive spastic paraplegia
Progressive spastic paraplegia 		59 1 10 0.11 1 0.25
CUI: C2673700
Disease: Brisk reflexes
Brisk reflexes 		31 7 7 0.11 1 1.0E-01
CUI: C1112256
Disease: Sensorimotor neuropathy
Sensorimotor neuropathy 		93 21 13 0.11 2 8.7E-02
CUI: C0034935
Disease: Babinski Reflex
Babinski Reflex 		218 11 25 0.11 1 7.1E-02
CUI: C0558845
Disease: Reflex, Ankle, Absent
Reflex, Ankle, Absent 		33 0 7 0.11 0 0
CUI: C4024610
Disease: Leg muscle stiffness
Leg muscle stiffness 		13 0 5 0.11 0 0
CUI: C0039273
Disease: Talipes cavus
Talipes cavus 		213 0 24 0.11 0 0